ZNF224 (GENE)

ZNF224
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2ELY, 2ELZ, 2EM0, 2EM6, 2EM7, 2EM8, 2EM9, 2EN1, 2EN8, 2ENA, 2ENC, 2EOQ, 2EOR, 2EQ4, 2YSP, 2YTH
Identifiers
Aliases	ZNF224, BMZF-2, BMZF2, KOX22, ZNF255, ZNF27, ZNF233, zinc finger protein 224
External IDs	OMIM: 194555; HomoloGene: 130663; GeneCards: ZNF224; OMA: ZNF224 - orthologs
Gene location ( Human)
Chr.	Chromosome 19 (human)
End	44,109,886 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; rectum; ; gastric mucosa; ; right uterine tube; ; left ovary; ; spleen; ; left lobe of thyroid gland; ; right ovary; ; right lobe of thyroid gland;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; DNA-binding transcription factor activity; metal ion binding; DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; intracellular anatomical structure; nuclear membrane; transcription repressor complex;
Biological process	negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II;
	Sources: Amigo / QuickGO
Orthologs
	7767
	n/a
	ENSG00000267680
	n/a
	Q9NZL3
	n/a
	NM_013398; NM_001321645
	n/a
	NP_001308574; NP_037530
	n/a
	Wikidata
View/Edit Human

Zinc finger protein 224 is a protein that in humans is encoded by the ZNF224 gene.^[3]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000267680 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ZNF224 zinc finger protein 224".

Medugno L, Florio F, Cesaro E, et al. (2007). "Differential expression and cellular localization of ZNF224 and ZNF255, two isoforms of the Krüppel-like zinc-finger protein family". Gene. 403 (1–2): 125–131. doi: 10.1016/j.gene.2007.07.036. PMID 17900823.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi: 10.1101/gr.2596504. PMC 528928. PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–12135. Bibcode: 2004PNAS..10112130B. doi: 10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Shannon M, Hamilton AT, Gordon L, et al. (2003). "Differential Expansion of Zinc-Finger Transcription Factor Loci in Homologous Human and Mouse Gene Clusters". Genome Res. 13 (6A): 1097–1110. doi: 10.1101/gr.963903. PMC 403638. PMID 12743021.
Medugno L, Costanzo P, Lupo A, et al. (2004). "A novel zinc finger transcriptional repressor, ZNF224, interacts with the negative regulatory element (AldA-NRE) and inhibits gene expression". FEBS Lett. 534 (1–3): 93–100. doi: 10.1016/S0014-5793(02)03783-3. PMID 12527367. S2CID 3087490.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode: 2002PNAS...9916899M. doi: 10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lee TH, Lwu S, Kim J, Pelletier J (2003). "Inhibition of Wilms tumor 1 transactivation by bone marrow zinc finger 2, a novel transcriptional repressor". J. Biol. Chem. 277 (47): 44826–44837. doi: 10.1074/jbc.M205667200. PMID 12239212.
Han ZG, Zhang QH, Ye M, et al. (2000). "Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB". J. Biol. Chem. 274 (50): 35741–35748. doi: 10.1074/jbc.274.50.35741. PMID 10585455.
Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–374. PMID 2288909.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000267680 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: ZNF224 zinc finger protein 224".

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