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Archive 1 |
Hello, all. It was initially my hope to try to have this done as part of Esperanza's proposal for an appreciation week to end on Wikipedia Day, January 15. However, several people have once again proposed the entirety of Esperanza for deletion, so that might not work. It was the intention of the Appreciation Week proposal to set aside a given time when the various individuals who have made significant, valuable contributions to the encyclopedia would be recognized and honored. I believe that, with some effort, this could still be done. My proposal is to, with luck, try to organize the various WikiProjects and other entities of wikipedia to take part in a larger celebrartion of its contributors to take place in January, probably beginning January 15, 2007. I have created yet another new subpage for myself (a weakness of mine, I'm afraid) at User talk:Badbilltucker/Appreciation Week where I would greatly appreciate any indications from the members of this project as to whether and how they might be willing and/or able to assist in recognizing the contributions of our editors. Thank you for your attention. Badbilltucker 17:03, 30 December 2006 (UTC)
Recruiting editors to make up for attrition is a constant task.
According to Wikipedia:WikiProject Council/Guide/WikiProject, the most effective methods is through the use of the project banner template. The guide suggests that these go on the Talk Pages of articles, and not on the article main page.
Additional recruitment tactics include trawling through Molecular Biology Projects and finding participants who list signaling as an interest of theirs, and inviting them directly. Similarly, users who list signaling as an interest on the user page. Tip for finding these: go to signal transduction or cell signaling and click on What Links Here - look for User Pages and Project Pages, etc. Biochemza, 12:12, 3 November 2007 (UTC)
Hi, I noticed an invitation to help on this project from some edit I had done on another page and so I wandered here and I'm willing to help, if you can use me (also, didn't mean to put up a big "new discussion" headline for this comment, but I didn't know where else to put it). Unfortunately I'm relatively new to the Wikipedia community, so I'm not really sure how to help.
I currently work in a signaling laboratory that focuses on nutrient signalling to the mTOR-S6 Kinase pathway. We do mostly in-vitro studies and have recently been interested in transcriptional regulation by the pathway.
I think this project is a great idea. I also think that the best way to organize it would be through diagrams, i.e. clickable diagrams akin to how Cell Signaling does it, although I understand that this would be extremely complicated. Best, Mhsia 18:17, 3 August 2006 (UTC)
Bravo guys. Wish I could help. How to depict information seems a point of interest. Hmmm, maybe I'll have something to say after boning up on it a bit. There is often a trade off between clarity and density, but a good 'architecture' can allow both. One problem seems to occur when one item has several different 'meanings' or functions. Perhaps some help from other communities, like logic, graphics, programmers, who?. How about Flash that splits/merges to show alternatives? Wblakesx 23:46, 18 October 2006 (UTC)wblakesx
Hi guy's you are doing a great job on the Hh pathway. I would be happy to help if you need any ideas or questions. I have helped create http://hedgehog.sfsu.edu I have done most of creation along with reading almost every article that has come out on the Hh pathway. The site is a little outdated due to the PI being very ill and funding for the project has decreased. However, I would really like to help you guys out on wikipedia if needed. Warmest regards, email me at drew007martin@gmail.com
This section deals with management of the actual project itself, such as the creation of templates, task forces, etc.
Anyone who works in the cell signaling field knows its a huge, messy, poorly understood field. I think we should break this WikiProject down into more manageable projects, grouped by broad subject area. I am quite specialised in my particular field, so I wouldn't really be able to create a list of these mini-projects, but I think if we added projects according to our specialisation, it would eventually flesh out into a nice list, by itself.
For example, I would add something like Tyrosine kinase signaling to the Projects section, and then that mini-project would obviously focus on tyrosine kinases. At a later stage, it might even be further subdivided (Receptor PTKs vs Non-receptor PTKs or whatever) - as the workload calls for it.
Any comments? Biochemza, 02:25, 3 November 2007 (UTC)
As this project grows, it might be handy to form task forces to focus on specific things. Like fixing Categorisation, or whatever. See Wikipedia:WikiProject_Council/Guide/Task_forces. Discussions? Biochemza, 11:33, 3 November 2007 (UTC)
Hey nice work on the templates, i'll start adding them to the appropriate articles and start expanding their content, one by one. Rockpocke t 23:50, 6 June 2006 (UTC)
I have recently created a banner for Wikipedia:WikiProject Biology which has assessment parameters. I notice that your existing banner does not. Given the amount of overlap in the biology sector, and the concerns expressed elsewhere about the proliferation of project banners, I was wondering whether the members of this project would be interested in perhaps utilizing the Biology banner, with a "drop down tab" for this project, perhaps similar to the {{ WPMILHIST}} banner. Doing so would permit for individual assessment for each project, as that is something the Military History banner does, while at the same time reducing the amount of banner "clutter" on talk pages. If you would be interested in such an arrangement, please let me know and I will work to revise the Biology banner to include the "drop-down" tab and make the other arrangements required for your project, as well as theirs, to have assessment data available. Thank you. John Carter 20:56, 27 April 2007 (UTC)
I think the templates used on these other pages might also be useful guidelines/starting points:
I think the lipid signaling navbox should be expanded to include many of the enzymes/substrates/products in Lipid_signaling. Biochemza, 20:10, 5 November 2007 (UTC)
Can someone create a userbox along the lines of "This user is a member of this project". Biochemza, 15:58, 2 November 2007 (UTC)
A Welcome template new participants. See Welcome Wagon. Biochemza,
Hello. The WikiProject Council has recently updated the Wikipedia:WikiProject Council/Directory. This new directory includes a variety of categories and subcategories which will, with luck, potentially draw new members to the projects who are interested in those specific subjects. Please review the directory and make any changes to the entries for your project that you see fit. There is also a directory of portals, at User:B2T2/Portal, listing all the existing portals. Feel free to add any of them to the portals or comments section of your entries in the directory. The three columns regarding assessment, peer review, and collaboration are included in the directory for both the use of the projects themselves and for that of others. Having such departments will allow a project to more quickly and easily identify its most important articles and its articles in greatest need of improvement. If you have not already done so, please consider whether your project would benefit from having departments which deal in these matters. It is my hope that all the changes to the directory can be finished by the first of next month. Please feel free to make any changes you see fit to the entries for your project before then. If you should have any questions regarding this matter, please do not hesitate to contact me. Thank you. B2T2 23:35, 25 October 2006 (UTC)
I think we should have a welcome wagon. Nothing quite as formal as a welcoming committee (because, frankly, that seems like too much hard work), but if participants are checking this project and notice someone new signed up, it would be nice to drop them a line on their Talk page to say hello and welcome. Creating a Project-specific Welcome template might be the way to go? Biochemza, 21:11, 3 November 2007 (UTC)
check out Burke's Reconnections and the Visual Thesaurus. Wblakesx 22:52, 19 November 2006 (UTC)wblakesx
JWSchmidt and I were talking about adding in signaling diagrams on the relevant protein pages.
One thing I thing would be useful would be if the diagrams were actually hyper-linked, such that you could click from the protein name in the figure to the relevant article.
There are complications, obviously, to the idea of having such diagrams:
1) Some proteins, like Akt for example, link into multipe signaling pathways
2) Not everyone agrees on all the signaling points
3) Some signaling interactions are tissue specific.
4) Some signaling interactions are cell-stage specific (for example there are differences in signaling between the proliferation-competent cell and the cell once it is differentiated into a particular tissue-type and becomes post-mitotic).
But even with these problems, it seems that giving the signaling context to every protein that participates in signaling pathways would be extremely useful.
This would require coordinating with the large "Protein" project and their templates as well... and would require a section for every protein that is in a signaling pathway as to its role in that pathway.
Just some suggestions...
Gacggt
19:00, 18 June 2006 (UTC)
Gacggt 12:03, 19 June 2006 (UTC)
Okay, this is what I think the main ideas/questions are:
Peter Z. Talk 19:19, 19 June 2006 (UTC)
one last question...
Gacggt 20:40, 19 June 2006 (UTC)
Peter Z.
Talk mentioned that he would incorporate the scheme used in my diagrams for the
TGF beta signaling pathway, which he did in the
JAK-STAT signaling pathway. I created a page in
my sandbox proposing a scheme that we can use in images in the project. I agree that the images should be drawn to a single standard and I think we should work out one. Check it out here (
proposed scheme) and tell me what you think and then we can move it over to the project page and iron out the details. --
GAThrawn22
07:58, 3 July 2006 (UTC)
I moved the page the proposed page to Wikipedia:WikiProject Molecular and Cellular Biology/Diagram guide. Feel free to take a look and make any changes, additions, or discuss the scheme. -- GAThrawn22 19:25, 8 July 2006 (UTC)
I am not sure that a single sucture for signaling pathway articles is going to work. Pathways are pretty abstract concepts and exist only as a biologist's way of organising their research... PS Otherwise I think this project is a good idea. A lot of quite important (I would think) articles on this subject are in a really sad state. I'll try to encourage more people to participate. The Meaning of Liff 20:18, 6 June 2006 (UTC)
What do you think of these names? ( source)
-- JWSchmidt 03:30, 25 June 2006 (UTC)
I propose to add links to most notable labs working on a particular pathway in external links sections of articles. It is too much to hope that the articles will always be maintained up to date. It could help students and researchers new to the subject get up to speed on the latest developments. As this could become a vehicle of shameless self promotion, we need strict criteria for inclusion. Generally, the lab must be accepted among the majority of researchers in the subject area as influential, but this is near impossible to verify. I suggest these rules:
-- Peter Z. Talk 20:21, 26 June 2006 (UTC)
Hi... actually I think this is too much of a judgement call. It seems fine to list references, and to point to seminal papers - but annointing a sub-set of signaling labs as the most important seems fraught with problems. Just my opinion. Also, one would point to different labs for different contexts, even in the same pathway. Sorry but I strongly disagree with this idea. Gacggt 20:28, 26 June 2006 (UTC)
I have just realised that we have both Category:Signal transduction and Category:Cell signaling. Now, we do need separate articles for these terms, but I don't think separate categories are justified. I suggest to move all articles to Cell signaling and get rid of signal transduction. I am not sure how category mechanics/bureaucracy works, need to look it up.
It is also about time we agreed on a category system. I suggest we create these subcategories in Category:Cell signaling: Signaling pathways, Ligands (alternatively Cell signaling ligands), Receptors (alternatively Cell signaling receptors), Kinases, Transcription factors. Articles relevant to a particular pathway could be linked together using navboxes, modelled after TGF_beta_signaling_pathway#Summary_table. If there are no objections, I'll proceed to sort things out. It's the best I can do until I get full text access to journals and can get back to writing. Peter Z. Talk 13:28, 8 July 2006 (UTC)
I agree. -- GAThrawn22 19:17, 8 July 2006 (UTC)
Great idea! Biochemza, 13:30, 2 November 2007 (UTC)
I have created the following sub-categories in (or moved them to sub-categories of) Category:Cell signaling:
Biochemza, 18:13, 2 November 2007 (UTC)
I propose that Category:Tyrosine kinase receptors be renamed to Category:Receptor tyrosine kinases. The first term implies that tyrosine kinases are ligands that bind to specific receptors, whereas the term actually means receptors that have a tyrosine kinase motif on the cytosolic domain, or discrete, soluble tyrosine kinases conformationally bound to the receptor cytosolic domain. I could be wrong though (I haven't actually clicked through and read all the articles linking to that category - who knows, maybe I would have learned something). What thoughts/disagreements/comments? Biochemza, 03:28, 3 November 2007 (UTC)
I think it would be really great to have a Cell Signaling Portal. Check out these featured Portals:
Biochemza, 11:52, 3 November 2007 (UTC)
Whoa!!! Adding choleseterol as a postranslation modification (what's the name of it - cholesteroylation or something? Do we have an article about this?) with roles in protein trafic and cell signaling?!? We thought we know everething about the ol' membrane fella - it's been researched for some half a century, at least. Why doesn't SHH-N stay anchored to the plasma membrane the way the mirystoylated proteins are (cholesterol in fully extended state is as long as myristate if not longer) but instead leaves the cell, does DISP have anything to do with it? Why is the presence of cholesterol moiety so important for the receptor/ligand recogntion? What would happen if the cholesterol moiety is cleaved off SHH-N outside the cell in a regulated manner? Would the reduction of cholesterol content inside the cells due to cholesterol lowering diets affect somehow these processes? Are there any drugs outthere that inhibit any of the cholesterol-dependent events - cholesterol attachment, excretion and PTCH binding? Sorry, i couldn't help it, i read this new stuff and my head started spinning around. -- Boris 03:25, 19 June 2006 (UTC)
Would anyone like to help me make a page for the GnRH regulating protein kisspeptin. There isn't one on Wikipedia yet.--JE.at.UWO U| T 18:35, 14 November 2006 (UTC)
Cross-posted at Wikipedia talk:WikiProject Molecular and Cellular Biology.
An editor has raised awareness to PAC-1 on WP:DRUGS. I thought some project contributors may have heard of it/be interested in contributing to the article. Thanks, Fvasconcellos 16:46, 26 December 2006 (UTC)
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Thanks. — Headbomb { ταλκ κοντριβς – WP Physics} 08:56, 15 March, 2009 (UTC)
Was browsing around when I noticed this wikiproject. Am I correct to assume that this wikiproject is not as active as it used to be? Or is there perhaps just not much to discuss on the talk page? Either way I was thinking of stepping up and merging this entire project under the Wikipedia:WikiProject Molecular and Cellular Biology project as a task force? Would anyone have any comments that they would like to bring up? Everything on this page will remain the same, only difference/change would be to merge the wikiproject template talk page tags as one (so the template would look like: {{WPMCB|cell-signaling=yes}}. My hope is that this might increase viewership levels of this particular project for those who might have an incling towards this field of molecular biology (via noticing this page from the MCB project). I shall also post this on the MCB proposal talk page. Cheers. Calaka ( talk) 11:08, 5 May 2009 (UTC)
Does anyone have any good techniques/suggestions/etc for outlining signal transduction outside or inside a cell without using cartoons/diagrams (i.e. some type of all-text approach)? --- kilbad ( talk) 01:33, 11 June 2009 (UTC)
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I already posted on the guest list (have no ideia if anyone looks at that), im a student of celular and molecular biology and i would like to contribute to the cell signaling project. As the title says i would be interted in starting or improving those topics, but I have no ideia how to incorporate all that, since it need referals to several diferent situation in cell metabolism. Should this be treated as a diferent subject to every diferent protein and marker on the cell? should diferent pages be created for diferent examples? All on the same page? example: Snares and Rabs participate on the same process and interact together, but they're on diferent wiki pages. Thank you Miguel AngeloR 04:37, 7 December 2010 (UTC) —Preceding unsigned comment added by Miguel AngeloR ( talk • contribs)
Any objections if I propose deletion of the signal transduction stub type? Category:Signal transduction stubs contains a rather arbitrary collection of 13 pages, most of which could go into Category:Receptor stubs or Category:Transmembrane receptor stubs. Thanks, ἀνυπόδητος ( talk) 17:14, 12 September 2011 (UTC)
Comments on Wikipedia:Village_pump_(idea_lab)#Static_vs_dynamic_topics:_seriously_outdated_articles will be appreciated, so we can get a general perspective on this. Thanks. History2007 ( talk) 13:28, 22 May 2012 (UTC)
Hello all! I’m working with the Saylor foundation to create a series of original, crowd-sourced textbooks that will be openly licensed and freely available on the web and within Saylor’s free, self-paced courses at Saylor.org. We are using Wikibooks as a platform to host this project and hope to garner the interest of existing members of the Wikibooks and Wikipedia community, as well as bring in new members! We thought that some of your members may be interested in contributing to our book Saylor.org's Cell Biology.( talk) -- Thomas Simpson ( talk) 17:36, 22 August 2012 (UTC)
I am planning on having students in an advanced Signal Transduction class edit Wikipedia pages as a class assignment for Spring 2013 semester. Everything they do should be related to Wikipedia:WikiProject Cell Signaling, but this project is listed as inactive on Wikipedia:WikiProject Molecular and Cellular Biology. At the end of the semester, I do not expect much continued activity within this WikiProject, so I am unsure as to whether to instruct my students to tag appropriate pages with the Cell Signaling WikiProject Banner or whether to work exclusively through WP:MCB. I'm still pretty new on Wikipedia and would appreciate advice from those who have been active here in the past. In addition, I would be grateful to anyone who is willing to help with reviewing articles. We have signed up with WEP and do have an Ambassador working with our class, but the more readers, the better the outcome will be. Many thanks. Biolprof ( talk) 05:11, 7 January 2013 (UTC)
Hi all,
I'm one of the students that is enrolled in Signal Transduction in Spring 2013, and I was wondering if I could get some feedback from anyone on these potential areas I have selected for topics. All of them are start-class pages on wikipedia, so I know information could definitely be added to them. I have also found a substantial amount of sources (primary sources and secondary sources, including review articles), and I have included several links to different articles with each topic. Again, any feedback would be great! Thanks in advanced, and I hope to hear back from some of you! MChapman5 ( talk) 07:50, 29 January 2013 (UTC)
Signal Transduction of Ubiquitin in Plant Immunity
I was toying with the idea of tying in several areas of molecular bio for this project. More specifically, I was doing some research on signaling in plant immunity to see how ubiquitin works in the signal transduction of their immunology. The page on plant immunity is only rated as a start, and they have a section dedicated to plant defense in signal transduction; yet there are no specific molecules or pathways displayed. However, doing a quick Google search, I pulled several scholarly articles from PubMed, the NCBI, and several Cell Bio journals that could definitely add to this information.
Here are some links:
RING finger domain and ubiquitylation function
This topic revolves around a protein domain known as RING finger domain. They play a role in the ubiquitin pathway; especially with cancer pathways, mitosis, and viral infection. This domain is a little more specific than say a broad topic like GPCR or RTK, but it still is general enough to encompass several areas of research and integration of topics. The wikipedia page I found on it lists it as a start-class, so it has a lot of room for development.
Here are some links:
Signaling in Heat Shock Proteins
Trying to pick a broad topic, I thought that maybe HSP would be an interesting thing to play around with. Wikipedia says that the page is a start-class, and it is of mid importance (which I agree with). However, there is much more information that could be added to this field--especially the fact that the HSP are involved in several modes of signaling. Topics relating the types of signaling and functions they serve in cells (both animal and plant) may be an interesting subject to explore for Wikipedia as well as the class lecture.
Here are some links:
I think I'm pretty committed to working on the SR protein page. Wikipedia rates it as a stub and low-importance, but I still believe it would be a good topic for my wikipedia project. The article is bare bones at best and could really use a lot of help and I've found a bunch of review papers that I think the page could benefit from.
Potential Articles
Even though wikipedia does not rate the SR protein page as high or even mid-importance, the page could be filled out significantly and wikipedia would be better because of it.
Any suggestions about wikipedia and SR proteins would be welcome and appreciated. BreCaitlin ( talk) 01:28, 1 February 2013 (UTC)
These are my potential articles for this assignment in my Signal Transduction course and my reasoning for my choices. I based most of my choices off of the research with which I am currently helping. This research involves working to produce vaccines for antigens specific to breast cancer cells. If you have any suggestions in relation to these articles, I am more than willing to take your recommendations or criticism. Thank you for your consideration.
Potential Article | Reasoning for Choice |
---|---|
Wnt Signaling Pathway | |
Frizzled |
|
Janus Kinase |
|
IL-2 receptor |
Adhesion-GPCRs There is a lot of empty space and plenty of areas where information can be added. I would like to also combine it with the following three links.
Crosstalk (biology) I would like to add more about GPCRs here.
GPR126 Add details about this adhesion GPCR.
ErbB Add more details about this Receptor Tyrosine Kinase pathway.
If anyone has a suggestion I am very open. Please add it to my talk page talk:Hakkinen2013
Hakkinen2013 ( talk) 01:18, 5 February 2013 (UTC)
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Gpruett2 ( talk) 07:23, 4 February 2013 (UTC)
Hello there! As you may already know, most WikiProjects here on Wikipedia struggle to stay active after they've been founded. I believe there is a lot of potential for WikiProjects to facilitate collaboration across subject areas, so I have submitted a grant proposal with the Wikimedia Foundation for the "WikiProject X" project. WikiProject X will study what makes WikiProjects succeed in retaining editors and then design a prototype WikiProject system that will recruit contributors to WikiProjects and help them run effectively. Please review the proposal here and leave feedback. If you have any questions, you can ask on the proposal page or leave a message on my talk page. Thank you for your time! (Also, sorry about the posting mistake earlier. If someone already moved my message to the talk page, feel free to remove this posting.) Harej ( talk) 22:47, 1 October 2014 (UTC)
Hello everyone!
You may have received a message from me earlier asking you to comment on my WikiProject X proposal. The good news is that WikiProject X is now live! In our first phase, we are focusing on research. At this time, we are looking for people to share their experiences with WikiProjects: good, bad, or neutral. We are also looking for WikiProjects that may be interested in trying out new tools and layouts that will make participating easier and projects easier to maintain. If you or your WikiProject are interested, check us out! Note that this is an opt-in program; no WikiProject will be required to change anything against its wishes. Please let me know if you have any questions. Thank you!
Note: To receive additional notifications about WikiProject X on this talk page, please add this page to Wikipedia:WikiProject X/Newsletter. Otherwise, this will be the last notification sent about WikiProject X.
Harej ( talk) 16:56, 14 January 2015 (UTC)
A requested move discussion has been initiated for Voltage-dependent calcium channel to be moved to Voltage-gated calcium channel. This page is of interest to this WikiProject and interested members may want to participate in the discussion here. — RMCD bot 23:30, 12 November 2017 (UTC)
A requested move discussion has been initiated for Mechanistic target of rapamycin to be moved to mTOR. This page is of interest to this WikiProject and interested members may want to participate in the discussion here. — RMCD bot 11:00, 24 February 2018 (UTC)
A requested move discussion has been initiated for MTOR to be moved to mTOR. This page is of interest to this WikiProject and interested members may want to participate in the discussion here. — RMCD bot 12:00, 3 March 2018 (UTC)
![]() | This
WikiProject is believed to be
inactive. Consider looking for
related projects for help or ask at the
Teahouse.
If you are not currently a project participant and wish to help you may still participate in the project or its parent project WikiProject Molecular Biology. This status should be changed if collaborative activity resumes. |
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Archive 1 |
Hello, all. It was initially my hope to try to have this done as part of Esperanza's proposal for an appreciation week to end on Wikipedia Day, January 15. However, several people have once again proposed the entirety of Esperanza for deletion, so that might not work. It was the intention of the Appreciation Week proposal to set aside a given time when the various individuals who have made significant, valuable contributions to the encyclopedia would be recognized and honored. I believe that, with some effort, this could still be done. My proposal is to, with luck, try to organize the various WikiProjects and other entities of wikipedia to take part in a larger celebrartion of its contributors to take place in January, probably beginning January 15, 2007. I have created yet another new subpage for myself (a weakness of mine, I'm afraid) at User talk:Badbilltucker/Appreciation Week where I would greatly appreciate any indications from the members of this project as to whether and how they might be willing and/or able to assist in recognizing the contributions of our editors. Thank you for your attention. Badbilltucker 17:03, 30 December 2006 (UTC)
Recruiting editors to make up for attrition is a constant task.
According to Wikipedia:WikiProject Council/Guide/WikiProject, the most effective methods is through the use of the project banner template. The guide suggests that these go on the Talk Pages of articles, and not on the article main page.
Additional recruitment tactics include trawling through Molecular Biology Projects and finding participants who list signaling as an interest of theirs, and inviting them directly. Similarly, users who list signaling as an interest on the user page. Tip for finding these: go to signal transduction or cell signaling and click on What Links Here - look for User Pages and Project Pages, etc. Biochemza, 12:12, 3 November 2007 (UTC)
Hi, I noticed an invitation to help on this project from some edit I had done on another page and so I wandered here and I'm willing to help, if you can use me (also, didn't mean to put up a big "new discussion" headline for this comment, but I didn't know where else to put it). Unfortunately I'm relatively new to the Wikipedia community, so I'm not really sure how to help.
I currently work in a signaling laboratory that focuses on nutrient signalling to the mTOR-S6 Kinase pathway. We do mostly in-vitro studies and have recently been interested in transcriptional regulation by the pathway.
I think this project is a great idea. I also think that the best way to organize it would be through diagrams, i.e. clickable diagrams akin to how Cell Signaling does it, although I understand that this would be extremely complicated. Best, Mhsia 18:17, 3 August 2006 (UTC)
Bravo guys. Wish I could help. How to depict information seems a point of interest. Hmmm, maybe I'll have something to say after boning up on it a bit. There is often a trade off between clarity and density, but a good 'architecture' can allow both. One problem seems to occur when one item has several different 'meanings' or functions. Perhaps some help from other communities, like logic, graphics, programmers, who?. How about Flash that splits/merges to show alternatives? Wblakesx 23:46, 18 October 2006 (UTC)wblakesx
Hi guy's you are doing a great job on the Hh pathway. I would be happy to help if you need any ideas or questions. I have helped create http://hedgehog.sfsu.edu I have done most of creation along with reading almost every article that has come out on the Hh pathway. The site is a little outdated due to the PI being very ill and funding for the project has decreased. However, I would really like to help you guys out on wikipedia if needed. Warmest regards, email me at drew007martin@gmail.com
This section deals with management of the actual project itself, such as the creation of templates, task forces, etc.
Anyone who works in the cell signaling field knows its a huge, messy, poorly understood field. I think we should break this WikiProject down into more manageable projects, grouped by broad subject area. I am quite specialised in my particular field, so I wouldn't really be able to create a list of these mini-projects, but I think if we added projects according to our specialisation, it would eventually flesh out into a nice list, by itself.
For example, I would add something like Tyrosine kinase signaling to the Projects section, and then that mini-project would obviously focus on tyrosine kinases. At a later stage, it might even be further subdivided (Receptor PTKs vs Non-receptor PTKs or whatever) - as the workload calls for it.
Any comments? Biochemza, 02:25, 3 November 2007 (UTC)
As this project grows, it might be handy to form task forces to focus on specific things. Like fixing Categorisation, or whatever. See Wikipedia:WikiProject_Council/Guide/Task_forces. Discussions? Biochemza, 11:33, 3 November 2007 (UTC)
Hey nice work on the templates, i'll start adding them to the appropriate articles and start expanding their content, one by one. Rockpocke t 23:50, 6 June 2006 (UTC)
I have recently created a banner for Wikipedia:WikiProject Biology which has assessment parameters. I notice that your existing banner does not. Given the amount of overlap in the biology sector, and the concerns expressed elsewhere about the proliferation of project banners, I was wondering whether the members of this project would be interested in perhaps utilizing the Biology banner, with a "drop down tab" for this project, perhaps similar to the {{ WPMILHIST}} banner. Doing so would permit for individual assessment for each project, as that is something the Military History banner does, while at the same time reducing the amount of banner "clutter" on talk pages. If you would be interested in such an arrangement, please let me know and I will work to revise the Biology banner to include the "drop-down" tab and make the other arrangements required for your project, as well as theirs, to have assessment data available. Thank you. John Carter 20:56, 27 April 2007 (UTC)
I think the templates used on these other pages might also be useful guidelines/starting points:
I think the lipid signaling navbox should be expanded to include many of the enzymes/substrates/products in Lipid_signaling. Biochemza, 20:10, 5 November 2007 (UTC)
Can someone create a userbox along the lines of "This user is a member of this project". Biochemza, 15:58, 2 November 2007 (UTC)
A Welcome template new participants. See Welcome Wagon. Biochemza,
Hello. The WikiProject Council has recently updated the Wikipedia:WikiProject Council/Directory. This new directory includes a variety of categories and subcategories which will, with luck, potentially draw new members to the projects who are interested in those specific subjects. Please review the directory and make any changes to the entries for your project that you see fit. There is also a directory of portals, at User:B2T2/Portal, listing all the existing portals. Feel free to add any of them to the portals or comments section of your entries in the directory. The three columns regarding assessment, peer review, and collaboration are included in the directory for both the use of the projects themselves and for that of others. Having such departments will allow a project to more quickly and easily identify its most important articles and its articles in greatest need of improvement. If you have not already done so, please consider whether your project would benefit from having departments which deal in these matters. It is my hope that all the changes to the directory can be finished by the first of next month. Please feel free to make any changes you see fit to the entries for your project before then. If you should have any questions regarding this matter, please do not hesitate to contact me. Thank you. B2T2 23:35, 25 October 2006 (UTC)
I think we should have a welcome wagon. Nothing quite as formal as a welcoming committee (because, frankly, that seems like too much hard work), but if participants are checking this project and notice someone new signed up, it would be nice to drop them a line on their Talk page to say hello and welcome. Creating a Project-specific Welcome template might be the way to go? Biochemza, 21:11, 3 November 2007 (UTC)
check out Burke's Reconnections and the Visual Thesaurus. Wblakesx 22:52, 19 November 2006 (UTC)wblakesx
JWSchmidt and I were talking about adding in signaling diagrams on the relevant protein pages.
One thing I thing would be useful would be if the diagrams were actually hyper-linked, such that you could click from the protein name in the figure to the relevant article.
There are complications, obviously, to the idea of having such diagrams:
1) Some proteins, like Akt for example, link into multipe signaling pathways
2) Not everyone agrees on all the signaling points
3) Some signaling interactions are tissue specific.
4) Some signaling interactions are cell-stage specific (for example there are differences in signaling between the proliferation-competent cell and the cell once it is differentiated into a particular tissue-type and becomes post-mitotic).
But even with these problems, it seems that giving the signaling context to every protein that participates in signaling pathways would be extremely useful.
This would require coordinating with the large "Protein" project and their templates as well... and would require a section for every protein that is in a signaling pathway as to its role in that pathway.
Just some suggestions...
Gacggt
19:00, 18 June 2006 (UTC)
Gacggt 12:03, 19 June 2006 (UTC)
Okay, this is what I think the main ideas/questions are:
Peter Z. Talk 19:19, 19 June 2006 (UTC)
one last question...
Gacggt 20:40, 19 June 2006 (UTC)
Peter Z.
Talk mentioned that he would incorporate the scheme used in my diagrams for the
TGF beta signaling pathway, which he did in the
JAK-STAT signaling pathway. I created a page in
my sandbox proposing a scheme that we can use in images in the project. I agree that the images should be drawn to a single standard and I think we should work out one. Check it out here (
proposed scheme) and tell me what you think and then we can move it over to the project page and iron out the details. --
GAThrawn22
07:58, 3 July 2006 (UTC)
I moved the page the proposed page to Wikipedia:WikiProject Molecular and Cellular Biology/Diagram guide. Feel free to take a look and make any changes, additions, or discuss the scheme. -- GAThrawn22 19:25, 8 July 2006 (UTC)
I am not sure that a single sucture for signaling pathway articles is going to work. Pathways are pretty abstract concepts and exist only as a biologist's way of organising their research... PS Otherwise I think this project is a good idea. A lot of quite important (I would think) articles on this subject are in a really sad state. I'll try to encourage more people to participate. The Meaning of Liff 20:18, 6 June 2006 (UTC)
What do you think of these names? ( source)
-- JWSchmidt 03:30, 25 June 2006 (UTC)
I propose to add links to most notable labs working on a particular pathway in external links sections of articles. It is too much to hope that the articles will always be maintained up to date. It could help students and researchers new to the subject get up to speed on the latest developments. As this could become a vehicle of shameless self promotion, we need strict criteria for inclusion. Generally, the lab must be accepted among the majority of researchers in the subject area as influential, but this is near impossible to verify. I suggest these rules:
-- Peter Z. Talk 20:21, 26 June 2006 (UTC)
Hi... actually I think this is too much of a judgement call. It seems fine to list references, and to point to seminal papers - but annointing a sub-set of signaling labs as the most important seems fraught with problems. Just my opinion. Also, one would point to different labs for different contexts, even in the same pathway. Sorry but I strongly disagree with this idea. Gacggt 20:28, 26 June 2006 (UTC)
I have just realised that we have both Category:Signal transduction and Category:Cell signaling. Now, we do need separate articles for these terms, but I don't think separate categories are justified. I suggest to move all articles to Cell signaling and get rid of signal transduction. I am not sure how category mechanics/bureaucracy works, need to look it up.
It is also about time we agreed on a category system. I suggest we create these subcategories in Category:Cell signaling: Signaling pathways, Ligands (alternatively Cell signaling ligands), Receptors (alternatively Cell signaling receptors), Kinases, Transcription factors. Articles relevant to a particular pathway could be linked together using navboxes, modelled after TGF_beta_signaling_pathway#Summary_table. If there are no objections, I'll proceed to sort things out. It's the best I can do until I get full text access to journals and can get back to writing. Peter Z. Talk 13:28, 8 July 2006 (UTC)
I agree. -- GAThrawn22 19:17, 8 July 2006 (UTC)
Great idea! Biochemza, 13:30, 2 November 2007 (UTC)
I have created the following sub-categories in (or moved them to sub-categories of) Category:Cell signaling:
Biochemza, 18:13, 2 November 2007 (UTC)
I propose that Category:Tyrosine kinase receptors be renamed to Category:Receptor tyrosine kinases. The first term implies that tyrosine kinases are ligands that bind to specific receptors, whereas the term actually means receptors that have a tyrosine kinase motif on the cytosolic domain, or discrete, soluble tyrosine kinases conformationally bound to the receptor cytosolic domain. I could be wrong though (I haven't actually clicked through and read all the articles linking to that category - who knows, maybe I would have learned something). What thoughts/disagreements/comments? Biochemza, 03:28, 3 November 2007 (UTC)
I think it would be really great to have a Cell Signaling Portal. Check out these featured Portals:
Biochemza, 11:52, 3 November 2007 (UTC)
Whoa!!! Adding choleseterol as a postranslation modification (what's the name of it - cholesteroylation or something? Do we have an article about this?) with roles in protein trafic and cell signaling?!? We thought we know everething about the ol' membrane fella - it's been researched for some half a century, at least. Why doesn't SHH-N stay anchored to the plasma membrane the way the mirystoylated proteins are (cholesterol in fully extended state is as long as myristate if not longer) but instead leaves the cell, does DISP have anything to do with it? Why is the presence of cholesterol moiety so important for the receptor/ligand recogntion? What would happen if the cholesterol moiety is cleaved off SHH-N outside the cell in a regulated manner? Would the reduction of cholesterol content inside the cells due to cholesterol lowering diets affect somehow these processes? Are there any drugs outthere that inhibit any of the cholesterol-dependent events - cholesterol attachment, excretion and PTCH binding? Sorry, i couldn't help it, i read this new stuff and my head started spinning around. -- Boris 03:25, 19 June 2006 (UTC)
Would anyone like to help me make a page for the GnRH regulating protein kisspeptin. There isn't one on Wikipedia yet.--JE.at.UWO U| T 18:35, 14 November 2006 (UTC)
Cross-posted at Wikipedia talk:WikiProject Molecular and Cellular Biology.
An editor has raised awareness to PAC-1 on WP:DRUGS. I thought some project contributors may have heard of it/be interested in contributing to the article. Thanks, Fvasconcellos 16:46, 26 December 2006 (UTC)
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Thanks. — Headbomb { ταλκ κοντριβς – WP Physics} 08:56, 15 March, 2009 (UTC)
Was browsing around when I noticed this wikiproject. Am I correct to assume that this wikiproject is not as active as it used to be? Or is there perhaps just not much to discuss on the talk page? Either way I was thinking of stepping up and merging this entire project under the Wikipedia:WikiProject Molecular and Cellular Biology project as a task force? Would anyone have any comments that they would like to bring up? Everything on this page will remain the same, only difference/change would be to merge the wikiproject template talk page tags as one (so the template would look like: {{WPMCB|cell-signaling=yes}}. My hope is that this might increase viewership levels of this particular project for those who might have an incling towards this field of molecular biology (via noticing this page from the MCB project). I shall also post this on the MCB proposal talk page. Cheers. Calaka ( talk) 11:08, 5 May 2009 (UTC)
Does anyone have any good techniques/suggestions/etc for outlining signal transduction outside or inside a cell without using cartoons/diagrams (i.e. some type of all-text approach)? --- kilbad ( talk) 01:33, 11 June 2009 (UTC)
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I already posted on the guest list (have no ideia if anyone looks at that), im a student of celular and molecular biology and i would like to contribute to the cell signaling project. As the title says i would be interted in starting or improving those topics, but I have no ideia how to incorporate all that, since it need referals to several diferent situation in cell metabolism. Should this be treated as a diferent subject to every diferent protein and marker on the cell? should diferent pages be created for diferent examples? All on the same page? example: Snares and Rabs participate on the same process and interact together, but they're on diferent wiki pages. Thank you Miguel AngeloR 04:37, 7 December 2010 (UTC) —Preceding unsigned comment added by Miguel AngeloR ( talk • contribs)
Any objections if I propose deletion of the signal transduction stub type? Category:Signal transduction stubs contains a rather arbitrary collection of 13 pages, most of which could go into Category:Receptor stubs or Category:Transmembrane receptor stubs. Thanks, ἀνυπόδητος ( talk) 17:14, 12 September 2011 (UTC)
Comments on Wikipedia:Village_pump_(idea_lab)#Static_vs_dynamic_topics:_seriously_outdated_articles will be appreciated, so we can get a general perspective on this. Thanks. History2007 ( talk) 13:28, 22 May 2012 (UTC)
Hello all! I’m working with the Saylor foundation to create a series of original, crowd-sourced textbooks that will be openly licensed and freely available on the web and within Saylor’s free, self-paced courses at Saylor.org. We are using Wikibooks as a platform to host this project and hope to garner the interest of existing members of the Wikibooks and Wikipedia community, as well as bring in new members! We thought that some of your members may be interested in contributing to our book Saylor.org's Cell Biology.( talk) -- Thomas Simpson ( talk) 17:36, 22 August 2012 (UTC)
I am planning on having students in an advanced Signal Transduction class edit Wikipedia pages as a class assignment for Spring 2013 semester. Everything they do should be related to Wikipedia:WikiProject Cell Signaling, but this project is listed as inactive on Wikipedia:WikiProject Molecular and Cellular Biology. At the end of the semester, I do not expect much continued activity within this WikiProject, so I am unsure as to whether to instruct my students to tag appropriate pages with the Cell Signaling WikiProject Banner or whether to work exclusively through WP:MCB. I'm still pretty new on Wikipedia and would appreciate advice from those who have been active here in the past. In addition, I would be grateful to anyone who is willing to help with reviewing articles. We have signed up with WEP and do have an Ambassador working with our class, but the more readers, the better the outcome will be. Many thanks. Biolprof ( talk) 05:11, 7 January 2013 (UTC)
Hi all,
I'm one of the students that is enrolled in Signal Transduction in Spring 2013, and I was wondering if I could get some feedback from anyone on these potential areas I have selected for topics. All of them are start-class pages on wikipedia, so I know information could definitely be added to them. I have also found a substantial amount of sources (primary sources and secondary sources, including review articles), and I have included several links to different articles with each topic. Again, any feedback would be great! Thanks in advanced, and I hope to hear back from some of you! MChapman5 ( talk) 07:50, 29 January 2013 (UTC)
Signal Transduction of Ubiquitin in Plant Immunity
I was toying with the idea of tying in several areas of molecular bio for this project. More specifically, I was doing some research on signaling in plant immunity to see how ubiquitin works in the signal transduction of their immunology. The page on plant immunity is only rated as a start, and they have a section dedicated to plant defense in signal transduction; yet there are no specific molecules or pathways displayed. However, doing a quick Google search, I pulled several scholarly articles from PubMed, the NCBI, and several Cell Bio journals that could definitely add to this information.
Here are some links:
RING finger domain and ubiquitylation function
This topic revolves around a protein domain known as RING finger domain. They play a role in the ubiquitin pathway; especially with cancer pathways, mitosis, and viral infection. This domain is a little more specific than say a broad topic like GPCR or RTK, but it still is general enough to encompass several areas of research and integration of topics. The wikipedia page I found on it lists it as a start-class, so it has a lot of room for development.
Here are some links:
Signaling in Heat Shock Proteins
Trying to pick a broad topic, I thought that maybe HSP would be an interesting thing to play around with. Wikipedia says that the page is a start-class, and it is of mid importance (which I agree with). However, there is much more information that could be added to this field--especially the fact that the HSP are involved in several modes of signaling. Topics relating the types of signaling and functions they serve in cells (both animal and plant) may be an interesting subject to explore for Wikipedia as well as the class lecture.
Here are some links:
I think I'm pretty committed to working on the SR protein page. Wikipedia rates it as a stub and low-importance, but I still believe it would be a good topic for my wikipedia project. The article is bare bones at best and could really use a lot of help and I've found a bunch of review papers that I think the page could benefit from.
Potential Articles
Even though wikipedia does not rate the SR protein page as high or even mid-importance, the page could be filled out significantly and wikipedia would be better because of it.
Any suggestions about wikipedia and SR proteins would be welcome and appreciated. BreCaitlin ( talk) 01:28, 1 February 2013 (UTC)
These are my potential articles for this assignment in my Signal Transduction course and my reasoning for my choices. I based most of my choices off of the research with which I am currently helping. This research involves working to produce vaccines for antigens specific to breast cancer cells. If you have any suggestions in relation to these articles, I am more than willing to take your recommendations or criticism. Thank you for your consideration.
Potential Article | Reasoning for Choice |
---|---|
Wnt Signaling Pathway | |
Frizzled |
|
Janus Kinase |
|
IL-2 receptor |
Adhesion-GPCRs There is a lot of empty space and plenty of areas where information can be added. I would like to also combine it with the following three links.
Crosstalk (biology) I would like to add more about GPCRs here.
GPR126 Add details about this adhesion GPCR.
ErbB Add more details about this Receptor Tyrosine Kinase pathway.
If anyone has a suggestion I am very open. Please add it to my talk page talk:Hakkinen2013
Hakkinen2013 ( talk) 01:18, 5 February 2013 (UTC)
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Gpruett2 ( talk) 07:23, 4 February 2013 (UTC)
Hello there! As you may already know, most WikiProjects here on Wikipedia struggle to stay active after they've been founded. I believe there is a lot of potential for WikiProjects to facilitate collaboration across subject areas, so I have submitted a grant proposal with the Wikimedia Foundation for the "WikiProject X" project. WikiProject X will study what makes WikiProjects succeed in retaining editors and then design a prototype WikiProject system that will recruit contributors to WikiProjects and help them run effectively. Please review the proposal here and leave feedback. If you have any questions, you can ask on the proposal page or leave a message on my talk page. Thank you for your time! (Also, sorry about the posting mistake earlier. If someone already moved my message to the talk page, feel free to remove this posting.) Harej ( talk) 22:47, 1 October 2014 (UTC)
Hello everyone!
You may have received a message from me earlier asking you to comment on my WikiProject X proposal. The good news is that WikiProject X is now live! In our first phase, we are focusing on research. At this time, we are looking for people to share their experiences with WikiProjects: good, bad, or neutral. We are also looking for WikiProjects that may be interested in trying out new tools and layouts that will make participating easier and projects easier to maintain. If you or your WikiProject are interested, check us out! Note that this is an opt-in program; no WikiProject will be required to change anything against its wishes. Please let me know if you have any questions. Thank you!
Note: To receive additional notifications about WikiProject X on this talk page, please add this page to Wikipedia:WikiProject X/Newsletter. Otherwise, this will be the last notification sent about WikiProject X.
Harej ( talk) 16:56, 14 January 2015 (UTC)
A requested move discussion has been initiated for Voltage-dependent calcium channel to be moved to Voltage-gated calcium channel. This page is of interest to this WikiProject and interested members may want to participate in the discussion here. — RMCD bot 23:30, 12 November 2017 (UTC)
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