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Is there a connection between obesity and failure to drink enough water? Freeknowledgecreator ( talk) 00:10, 13 February 2020 (UTC)
I've previously heard some confidential information that a particular supercentenarian (I'm obviously not going to say which one) could have lived for an additional several days or several weeks had they not been given an incorrect dosage of blood thinner. I've also heard that this blood thinner was given to them in order to deal with an existing medical condition that they had.
In turn, this motivates me to ask--what medical conditions (including life-threatening ones) require blood thinner to treat? Any thoughts on this? 68.96.93.207 ( talk) 00:15, 13 February 2020 (UTC)
I know someone middle age who is on long term warfarin after a deep vein thrombosis incident. There was a known family history, and the only other risk factor I'm aware of would be weight. Our article has some limited discussion of such management. Note that using warfarin requires frequent testing to ensure that the patient is at the desired INR level.
For an older person, I gather that anticogulants may be used after a cardioembolic ischemic stroke or especially recurrent ischemic stroke in certain circumstances. [3] [4] [5] [6] [7] [8] [9] As is often the case in medicine, it's a case of balancing what is known or believed about the cause and risks e.g. Valvular heart disease, atrial fibrillation since the side effect is an increased risk of major bleeds so an increased risk of haemorrhagic stroke and other things. And newer anticougulants, especially directly acting oral anticoagulants are changing things.
In reference to the event which inspired this question remember also that if a patient died in 2001, this would be before some of the data. So for example, using warfarin may have been considered reasonable at the time even if it's now considered to not be the case.
As mentioned by Nunh-huh, in patients with an identified atrial fibrillation it may be considered best practice to prescribe anticoagulants to manage the risks from thrombosis (which I think would particularly include stroke but also others like myocardial infarction [10] [11]) even before an identified event, again depending on risk factors (which would include age) [12].
My 86 year old aunt has been on rat poison for most of her life due to a hole in her heart. Greglocock ( talk) 22:02, 13 February 2020 (UTC)
I'm looking for references about unbinding tannins from salivary proteins. I can find a lot about binding, causes and effects. I can't find anything on unbinding. Anyone better at searching articles? 135.84.167.41 ( talk) 18:46, 13 February 2020 (UTC)
Thanks. With this information, I have been able to find a few papers looking at using specific proteins and fats as agents to unbind tannins from salivary proteins and onto other proteins. Nothing very useful, but at least I'm making headway. 135.84.167.41 ( talk) 15:29, 18 February 2020 (UTC)
Science desk | ||
---|---|---|
< February 12 | << Jan | February | Mar >> | Current desk > |
Welcome to the Wikipedia Science Reference Desk Archives |
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The page you are currently viewing is a transcluded archive page. While you can leave answers for any questions shown below, please ask new questions on one of the current reference desk pages. |
Is there a connection between obesity and failure to drink enough water? Freeknowledgecreator ( talk) 00:10, 13 February 2020 (UTC)
I've previously heard some confidential information that a particular supercentenarian (I'm obviously not going to say which one) could have lived for an additional several days or several weeks had they not been given an incorrect dosage of blood thinner. I've also heard that this blood thinner was given to them in order to deal with an existing medical condition that they had.
In turn, this motivates me to ask--what medical conditions (including life-threatening ones) require blood thinner to treat? Any thoughts on this? 68.96.93.207 ( talk) 00:15, 13 February 2020 (UTC)
I know someone middle age who is on long term warfarin after a deep vein thrombosis incident. There was a known family history, and the only other risk factor I'm aware of would be weight. Our article has some limited discussion of such management. Note that using warfarin requires frequent testing to ensure that the patient is at the desired INR level.
For an older person, I gather that anticogulants may be used after a cardioembolic ischemic stroke or especially recurrent ischemic stroke in certain circumstances. [3] [4] [5] [6] [7] [8] [9] As is often the case in medicine, it's a case of balancing what is known or believed about the cause and risks e.g. Valvular heart disease, atrial fibrillation since the side effect is an increased risk of major bleeds so an increased risk of haemorrhagic stroke and other things. And newer anticougulants, especially directly acting oral anticoagulants are changing things.
In reference to the event which inspired this question remember also that if a patient died in 2001, this would be before some of the data. So for example, using warfarin may have been considered reasonable at the time even if it's now considered to not be the case.
As mentioned by Nunh-huh, in patients with an identified atrial fibrillation it may be considered best practice to prescribe anticoagulants to manage the risks from thrombosis (which I think would particularly include stroke but also others like myocardial infarction [10] [11]) even before an identified event, again depending on risk factors (which would include age) [12].
My 86 year old aunt has been on rat poison for most of her life due to a hole in her heart. Greglocock ( talk) 22:02, 13 February 2020 (UTC)
I'm looking for references about unbinding tannins from salivary proteins. I can find a lot about binding, causes and effects. I can't find anything on unbinding. Anyone better at searching articles? 135.84.167.41 ( talk) 18:46, 13 February 2020 (UTC)
Thanks. With this information, I have been able to find a few papers looking at using specific proteins and fats as agents to unbind tannins from salivary proteins and onto other proteins. Nothing very useful, but at least I'm making headway. 135.84.167.41 ( talk) 15:29, 18 February 2020 (UTC)