Wade Hampton may refer to the following people:

People

• Wade Hampton I (1752–1835), American soldier in Revolutionary War and War of 1812 and U.S. congressman
• Wade Hampton II (1791–1858), American plantation owner and soldier in War of 1812
• Wade Hampton III (1818–1902), American Civil War soldier and politician; elected Governor and Senator of South Carolina, opponent of Reconstruction
• William Wade Hampton (1854–1928), Florida lawyer commonly known as Wade Hampton
• Wade Hampton Frost (1880-1938), professor of epidemiology
• Wade Randolph Hampton, an American DJ active since the mid-1990s

Places

• Kusilvak Census Area, Alaska, formerly Wade Hampton Census Area
• Wade Hampton, South Carolina
• Wade Hampton Boulevard

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