WDRE may refer to:

Radio stations

• WDRE, a radio station (100.5 FM) currently licensed to Susquehanna, Pennsylvania, United States, broadcasting an oldies format in the Binghamton, NY radio market.

Former radio stations

• WPTY, a radio station (105.3 FM) licensed to Calverton-Roanoke, New York, United States, which used the WDRE call sign from 2004 to 2009
• WBON, a radio station (98.5 FM) licensed to Westhampton, New York, United States, which used the WDRE call sign from 1997 to 2004
• WPHI-FM, a radio station (103.9 FM) licensed to Jenkintown, Pennsylvania, United States, which used the WDRE call sign from 1996 to 1997
• WFME-FM, a radio station (92.7 FM) licensed to Garden City, New York, United States, which used the WDRE call sign from 1987 to 1996
• WRWB-FM, a radio station (99.3 FM) licensed to Ellenville, New York, United States, which used the WDRE call sign from 1981 to 1984

Other meanings

• Western Desert Railway Extension, a railway in North Africa during the Second World War

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