VVD-118313 is a chemical compound which acts as a potent and selective negative
allosteric modulator of
JAK1, and was developed for research into the treatment of inflammatory diseases, especially chronic inflammation involved in the development of
cancer.[1][2][3][4]
^Silvennoinen O, Haikarainen T, Virtanen A (December 2022). "Aiming for the pocket". Nature Chemical Biology. 18 (12): 1296–1297.
doi:
10.1038/s41589-022-01120-5.
PMID36097296.
VVD-118313 is a chemical compound which acts as a potent and selective negative
allosteric modulator of
JAK1, and was developed for research into the treatment of inflammatory diseases, especially chronic inflammation involved in the development of
cancer.[1][2][3][4]
^Silvennoinen O, Haikarainen T, Virtanen A (December 2022). "Aiming for the pocket". Nature Chemical Biology. 18 (12): 1296–1297.
doi:
10.1038/s41589-022-01120-5.
PMID36097296.