VG-1 is a B cell line which was derived from primary effusion lymphoma (PEL) ( Lu et al. 2009). It was first established in 2000 by David T. Scadden’s group at Massachusetts General Hospital. It is infected with Kaposi's sarcoma-associated herpesvirus (KSHV), but negative with Epstein–Barr virus (EBV) ( Brander et al. 2000).
References
- Brander, C.; Suscovich, T.; Lee, Y.; Nguyen, P.T.; O'Connor, P.; Seebach, J.; Jones, N.G.; van Gorder, M.; Walker, B.D.; Scadden, D.T. (2000), "Impaired CTL Recognition of Cells Latently Infected with Kaposi's Sarcoma-Associated Herpes Virus", J Immunol, vol. 165, no. 4, pp. 2077–83, doi: 10.4049/jimmunol.165.4.2077, PMID 10925292
- Lu, P.; Yang, C.; Guasparri, I.; Harrington, W.; Wang, Y.L.; Cesarman, E. (2009), "Early Events of B-cell Receptor Signaling are not Essential for the Proliferation and Viability of AIDS-Related Lymphoma", Leukemia, vol. 23, no. 4, pp. 807–10, doi: 10.1038/leu.2008.304, PMID 18987659
External links
 | This cell biology article is a stub. You can help Wikipedia by expanding it. |
VG-1 is a B cell line which was derived from primary effusion lymphoma (PEL) ( Lu et al. 2009). It was first established in 2000 by David T. Scadden’s group at Massachusetts General Hospital. It is infected with Kaposi's sarcoma-associated herpesvirus (KSHV), but negative with Epstein–Barr virus (EBV) ( Brander et al. 2000).
References
- Brander, C.; Suscovich, T.; Lee, Y.; Nguyen, P.T.; O'Connor, P.; Seebach, J.; Jones, N.G.; van Gorder, M.; Walker, B.D.; Scadden, D.T. (2000), "Impaired CTL Recognition of Cells Latently Infected with Kaposi's Sarcoma-Associated Herpes Virus", J Immunol, vol. 165, no. 4, pp. 2077–83, doi: 10.4049/jimmunol.165.4.2077, PMID 10925292
- Lu, P.; Yang, C.; Guasparri, I.; Harrington, W.; Wang, Y.L.; Cesarman, E. (2009), "Early Events of B-cell Receptor Signaling are not Essential for the Proliferation and Viability of AIDS-Related Lymphoma", Leukemia, vol. 23, no. 4, pp. 807–10, doi: 10.1038/leu.2008.304, PMID 18987659
External links
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