JFW | T@lk 17:06, 24 July 2008 (UTC):It probably makes more sense for the content of basophil activation to be merged with basophil granulocyte.
JFW | T@lk 17:51, 24 July 2008 (UTC):If the test is not being used today, I would not mention it in allergy. That would be premature.
men | T@lk 20:06, 24 July 2008 (UTC): can some one who is autoconfirmed or an administrator plz activate the picturelink to my article basophil activation
men | T@lk 20:31, 24 July 2008 (UTC): hmm... i uploaded it on wiki commons, and it actually worked (someone activated it i think), but then i accidently deleted the article, and now the pic permission is gone again. the filename is "Basophlie activation.JPG" iknow spelling is wrong :)
men | T@lk 20:41, 24 July 2008 (UTC): i uploaded it again
http://commons.wikimedia.org/wiki/Image:Basophile_activation.JPG
http://commons.wikimedia.org/wiki/Image:Basophil_activation.JPG
men | T@lk 20:50, 24 July 2008 (UTC): Thanks for keeping cool with these newbies ;)
Hi there Menue. My apologies for the delayed response - I was enjoying myself way too much on vacation. You were correct in your question - the high affinity Fcε receptor binds IgE with no bound antigen. When an antigen is present, it will crosslink the Fc receptors (in other words, bind to more than one IgE molecule attached to individual Fc receptors) to activate the cell (mast, basophil, eosinophil) and trigger degranulation. This is described in the Immunobiology textbook that is free online at NCBI. I'm not quite sure I follow the two figures that you linked on my talk-page - perhaps a caption would help? Is there a relevance to the FITC labeled antigen, for instance? Good to see a new editor on the immunology pages! Best wishes, ~ Ciar ~ (Talk to me!) 08:07, 27 July 2008 (UTC)
JFW | T@lk 17:06, 24 July 2008 (UTC):It probably makes more sense for the content of basophil activation to be merged with basophil granulocyte.
JFW | T@lk 17:51, 24 July 2008 (UTC):If the test is not being used today, I would not mention it in allergy. That would be premature.
men | T@lk 20:06, 24 July 2008 (UTC): can some one who is autoconfirmed or an administrator plz activate the picturelink to my article basophil activation
men | T@lk 20:31, 24 July 2008 (UTC): hmm... i uploaded it on wiki commons, and it actually worked (someone activated it i think), but then i accidently deleted the article, and now the pic permission is gone again. the filename is "Basophlie activation.JPG" iknow spelling is wrong :)
men | T@lk 20:41, 24 July 2008 (UTC): i uploaded it again
http://commons.wikimedia.org/wiki/Image:Basophile_activation.JPG
http://commons.wikimedia.org/wiki/Image:Basophil_activation.JPG
men | T@lk 20:50, 24 July 2008 (UTC): Thanks for keeping cool with these newbies ;)
Hi there Menue. My apologies for the delayed response - I was enjoying myself way too much on vacation. You were correct in your question - the high affinity Fcε receptor binds IgE with no bound antigen. When an antigen is present, it will crosslink the Fc receptors (in other words, bind to more than one IgE molecule attached to individual Fc receptors) to activate the cell (mast, basophil, eosinophil) and trigger degranulation. This is described in the Immunobiology textbook that is free online at NCBI. I'm not quite sure I follow the two figures that you linked on my talk-page - perhaps a caption would help? Is there a relevance to the FITC labeled antigen, for instance? Good to see a new editor on the immunology pages! Best wishes, ~ Ciar ~ (Talk to me!) 08:07, 27 July 2008 (UTC)