Below is a list of causes of macrocephaly from Swaiman's pediatric neurology: principles and practice noted in The Little Black Book of Neurology [1] [2]:
Macrocephaly is customarily diagnosed if head circumference is greater than two standard deviations (SDs) above the mean. [3] Relative macrocephaly occurs if the measure is less than two SDs above the mean, but is disproportionately above that when ethnicity and stature are considered.
Relative macrocephaly is likely to have been inherited by one or both parents and is considered benign or megalencephaly and is not associated with neurological disorders [4]. Diagnosis can be determined in utero or develop within eighteen 18-24 months after birth in some cases where head circumference tends to stabilize in infants [5]. Diagnosis in infants includes measuring the circumference of the child's head and comparing how significant it falls above the 97.5 percentile of children similar to their demographic and then check if there is any intracranial pressure present in the child [4]. If a patient is suspected of having macrocephaly molecular testing will be used to confirm diagnosis.
Neurodevelopment is also assessed for all cases and suspected cases of macrocephaly to determine if and what treatments may be needed and whether or not other syndromes may be present or likely to develop.
Treatment varies depending on whether or not it occurs with other medical conditions in the child and where cerebrospinal fluid is present [5].
Below is a list of syndromes associated with macrocephaly. [6]
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Below is a list of causes of macrocephaly from Swaiman's pediatric neurology: principles and practice noted in The Little Black Book of Neurology [1] [2]:
Macrocephaly is customarily diagnosed if head circumference is greater than two standard deviations (SDs) above the mean. [3] Relative macrocephaly occurs if the measure is less than two SDs above the mean, but is disproportionately above that when ethnicity and stature are considered.
Relative macrocephaly is likely to have been inherited by one or both parents and is considered benign or megalencephaly and is not associated with neurological disorders [4]. Diagnosis can be determined in utero or develop within eighteen 18-24 months after birth in some cases where head circumference tends to stabilize in infants [5]. Diagnosis in infants includes measuring the circumference of the child's head and comparing how significant it falls above the 97.5 percentile of children similar to their demographic and then check if there is any intracranial pressure present in the child [4]. If a patient is suspected of having macrocephaly molecular testing will be used to confirm diagnosis.
Neurodevelopment is also assessed for all cases and suspected cases of macrocephaly to determine if and what treatments may be needed and whether or not other syndromes may be present or likely to develop.
Treatment varies depending on whether or not it occurs with other medical conditions in the child and where cerebrospinal fluid is present [5].
Below is a list of syndromes associated with macrocephaly. [6]
{{
cite web}}
: CS1 maint: url-status (
link)
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cite book}}
: CS1 maint: extra punctuation (
link) CS1 maint: others (
link)
{{
cite web}}
: CS1 maint: url-status (
link)
{{
cite book}}
: CS1 maint: extra punctuation (
link) CS1 maint: others (
link)