The article is very thorough on the history of the virus, but has nothing on the life cycle or structure of the virus. This is a clear difference from the Dengue virus which has sections on life-cycle and structure (with sub-sections for specific proteins and genomes. There is also little information as to the symptoms of the disease in cows or humans. Cowpox could use much more scientific information as opposed to purely historical information.
The best addition I could make would be new paragraph on the life-cycle and structure of the Cowpox virus. The key points will be:
- Classification and structure of virus (enveloped vs. non, what sort of genomic material, etc.)
- Method of infection
- Place of replication, means, etc.
I will use the following review articles, plus other possible reviews as I find them: "Zoonotic Poxviruses Associated with Companion Animals," [1] "Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily," [2] and "Cowpox virus infection: an emerging health threat." [3]
Cowpox is a member of the Poxviridae family of viruses, in the genus Orthopoxvirus. [2] These are dsDNA viruses, part of Baltimore Group I. These are very large and complex enveloped viruses with a single, large, linear dsDNA virion. [4] Cowpox typically infects through the skin, causing lesions at the place of contact with the infected host. [1] Cowpox has a large range of possible hosts, ranging from cattle, to rats, to humans. In animal hosts, the symptoms can range from asymptomatic to death: in humans it generally appears as a localized lesion. [1] Today, it is primarily found in Europe and Western Asia in wild rodents. [1]
 | This is a user sandbox of
WildcatRed1. You can use it for testing or practicing edits. This is not the sandbox where you should draft your assigned article for a dashboard.wikiedu.org course. To find the right sandbox for your assignment, visit your Dashboard course page and follow the Sandbox Draft link for your assigned article in the My Articles section. |
- ^
a
b
c
d Tack, Danielle M.; Reynolds, Mary G. (2011-11-17).
"Zoonotic Poxviruses Associated with Companion Animals". Animals. 1 (4): 377–395.
doi:
10.3390/ani1040377.
ISSN
2076-2615.
PMC
4513476.
PMID
26486622.
{{ cite journal}}: CS1 maint: PMC format ( link) CS1 maint: unflagged free DOI ( link) - ^
a
b Nelson, Christopher; Epperson, Megan; Singh, Sukrit; Elliott, Jabari; Fremont, Daved (2015-08-28).
"Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily". Viruses. 7 (9): 4873–4893.
doi:
10.3390/v7092848.
ISSN
1999-4915.
PMC
4584292.
PMID
26343707.
{{ cite journal}}: CS1 maint: PMC format ( link) CS1 maint: unflagged free DOI ( link) -
^ Vorou, Rengina M; Papavassiliou, Vassilios G; Pierroutsakos, Ioannis N (2008-04).
"Cowpox virus infection: an emerging health threat:". Current Opinion in Infectious Diseases. 21 (2): 153–156.
doi:
10.1097/QCO.0b013e3282f44c74.
ISSN
0951-7375.
{{ cite journal}}: Check date values in:|date=( help) -
^ Doellinger, Joerg; Schaade, Lars; Nitsche, Andreas (2015-11-10).
"Comparison of the Cowpox Virus and Vaccinia Virus Mature Virion Proteome: Analysis of the Species- and Strain-Specific Proteome". PLoS ONE. 10 (11).
doi:
10.1371/journal.pone.0141527.
ISSN
1932-6203.
PMC
4640714.
PMID
26556597.
{{ cite journal}}: CS1 maint: unflagged free DOI ( link)
The article is very thorough on the history of the virus, but has nothing on the life cycle or structure of the virus. This is a clear difference from the Dengue virus which has sections on life-cycle and structure (with sub-sections for specific proteins and genomes. There is also little information as to the symptoms of the disease in cows or humans. Cowpox could use much more scientific information as opposed to purely historical information.
The best addition I could make would be new paragraph on the life-cycle and structure of the Cowpox virus. The key points will be:
- Classification and structure of virus (enveloped vs. non, what sort of genomic material, etc.)
- Method of infection
- Place of replication, means, etc.
I will use the following review articles, plus other possible reviews as I find them: "Zoonotic Poxviruses Associated with Companion Animals," [1] "Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily," [2] and "Cowpox virus infection: an emerging health threat." [3]
Cowpox is a member of the Poxviridae family of viruses, in the genus Orthopoxvirus. [2] These are dsDNA viruses, part of Baltimore Group I. These are very large and complex enveloped viruses with a single, large, linear dsDNA virion. [4] Cowpox typically infects through the skin, causing lesions at the place of contact with the infected host. [1] Cowpox has a large range of possible hosts, ranging from cattle, to rats, to humans. In animal hosts, the symptoms can range from asymptomatic to death: in humans it generally appears as a localized lesion. [1] Today, it is primarily found in Europe and Western Asia in wild rodents. [1]
| This is a user sandbox of
WildcatRed1. You can use it for testing or practicing edits. This is not the sandbox where you should draft your assigned article for a dashboard.wikiedu.org course. To find the right sandbox for your assignment, visit your Dashboard course page and follow the Sandbox Draft link for your assigned article in the My Articles section. |
- ^
a
b
c
d Tack, Danielle M.; Reynolds, Mary G. (2011-11-17).
"Zoonotic Poxviruses Associated with Companion Animals". Animals. 1 (4): 377–395.
doi:
10.3390/ani1040377.
ISSN
2076-2615.
PMC
4513476.
PMID
26486622.
{{ cite journal}}: CS1 maint: PMC format ( link) CS1 maint: unflagged free DOI ( link) - ^
a
b Nelson, Christopher; Epperson, Megan; Singh, Sukrit; Elliott, Jabari; Fremont, Daved (2015-08-28).
"Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily". Viruses. 7 (9): 4873–4893.
doi:
10.3390/v7092848.
ISSN
1999-4915.
PMC
4584292.
PMID
26343707.
{{ cite journal}}: CS1 maint: PMC format ( link) CS1 maint: unflagged free DOI ( link) -
^ Vorou, Rengina M; Papavassiliou, Vassilios G; Pierroutsakos, Ioannis N (2008-04).
"Cowpox virus infection: an emerging health threat:". Current Opinion in Infectious Diseases. 21 (2): 153–156.
doi:
10.1097/QCO.0b013e3282f44c74.
ISSN
0951-7375.
{{ cite journal}}: Check date values in:|date=( help) -
^ Doellinger, Joerg; Schaade, Lars; Nitsche, Andreas (2015-11-10).
"Comparison of the Cowpox Virus and Vaccinia Virus Mature Virion Proteome: Analysis of the Species- and Strain-Specific Proteome". PLoS ONE. 10 (11).
doi:
10.1371/journal.pone.0141527.
ISSN
1932-6203.
PMC
4640714.
PMID
26556597.
{{ cite journal}}: CS1 maint: unflagged free DOI ( link)