From Wikipedia, the free encyclopedia

GATA transcription factors have been correlated to their broader influence on stem cell development. Findings however, have pointed to a more direct influence by GATA transcription factors, as they are salient components in the more concentrated regulation of gene expression. Data points to the roles GATA transcription factors play in stages past early development in endocrine organs. [1]

Despite GATA’s influence on endocrine organs and cell development, they have a complex relation to the development and growth of breast cancer. Its immediate influence is not yet known, its high risk for mutation however, makes determining the immediate influence of paramount importance in battling breast cancer. [2]

  1. ^ Viger, Robert S; Guittot, Séverine Mazaud; Anttonen, Mikko; Wilson, David B; Heikinheimo, Markku (2008-04-01). "Role of the GATA Family of Transcription Factors in Endocrine Development, Function, and Disease". Molecular Endocrinology. 22 (4): 781–798. doi: 10.1210/me.2007-0513. ISSN  0888-8809.
  2. ^ Du, Feng; Yuan, Peng; Wang, Teng; Zhao, Jiuda; Zhao, Zitong; Luo, Yang; Xu, Binghe (2015-11). "The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review". Medicinal Research Reviews. 35 (6): 1300–1315. doi: 10.1002/med.21362. ISSN  1098-1128. PMID  26313026. {{ cite journal}}: Check date values in: |date= ( help)
From Wikipedia, the free encyclopedia

GATA transcription factors have been correlated to their broader influence on stem cell development. Findings however, have pointed to a more direct influence by GATA transcription factors, as they are salient components in the more concentrated regulation of gene expression. Data points to the roles GATA transcription factors play in stages past early development in endocrine organs. [1]

Despite GATA’s influence on endocrine organs and cell development, they have a complex relation to the development and growth of breast cancer. Its immediate influence is not yet known, its high risk for mutation however, makes determining the immediate influence of paramount importance in battling breast cancer. [2]

  1. ^ Viger, Robert S; Guittot, Séverine Mazaud; Anttonen, Mikko; Wilson, David B; Heikinheimo, Markku (2008-04-01). "Role of the GATA Family of Transcription Factors in Endocrine Development, Function, and Disease". Molecular Endocrinology. 22 (4): 781–798. doi: 10.1210/me.2007-0513. ISSN  0888-8809.
  2. ^ Du, Feng; Yuan, Peng; Wang, Teng; Zhao, Jiuda; Zhao, Zitong; Luo, Yang; Xu, Binghe (2015-11). "The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review". Medicinal Research Reviews. 35 (6): 1300–1315. doi: 10.1002/med.21362. ISSN  1098-1128. PMID  26313026. {{ cite journal}}: Check date values in: |date= ( help)

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