![]() | |
Clinical data | |
---|---|
Trade names | Zanosar |
AHFS/ Drugs.com | Monograph |
MedlinePlus | a684053 |
Routes of administration | Intravenous |
Drug class | Alkylating agent [1] |
Legal status | |
Legal status |
|
Pharmacokinetic data | |
Bioavailability | 17–25% (100% if IV) |
Metabolism | Liver, kidney |
Elimination half-life | 35–40 minutes |
Identifiers | |
| |
Chemical and physical data | |
Formula | C8H15N3O7 |
Molar mass | 265.222 g·mol−1 |
3D model ( JSmol) | |
| |
| |
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Streptozotocin, also known as streptozocin (STZ), is a medication used for treating certain islet cell cancer of the pancreas, carcinoid tumor, and pancreatic adenocarcinoma. [1] It is given by injection into a vein. [1]
Common side effects include nausea, kidney problems, and bone marrow suppression. [1] Other side effects may include liver problems, confusion, and pain at the site of injection. [1] Use during pregnancy may harm the baby. [1] It is a alkylating agent. [1]
Streptozotocin was approved for medical use in the United States in 1982. [1] In the United Kingdom it cost the NHS about £570 per 1 gram as of 2021. [2] This amount in the United States costs about 370 USD. [3] It is sold under the brand name Zanosar among others. [1]
{{
cite book}}
: CS1 maint: date format (
link)
![]() | |
Clinical data | |
---|---|
Trade names | Zanosar |
AHFS/ Drugs.com | Monograph |
MedlinePlus | a684053 |
Routes of administration | Intravenous |
Drug class | Alkylating agent [1] |
Legal status | |
Legal status |
|
Pharmacokinetic data | |
Bioavailability | 17–25% (100% if IV) |
Metabolism | Liver, kidney |
Elimination half-life | 35–40 minutes |
Identifiers | |
| |
Chemical and physical data | |
Formula | C8H15N3O7 |
Molar mass | 265.222 g·mol−1 |
3D model ( JSmol) | |
| |
| |
![]() ![]() |
Streptozotocin, also known as streptozocin (STZ), is a medication used for treating certain islet cell cancer of the pancreas, carcinoid tumor, and pancreatic adenocarcinoma. [1] It is given by injection into a vein. [1]
Common side effects include nausea, kidney problems, and bone marrow suppression. [1] Other side effects may include liver problems, confusion, and pain at the site of injection. [1] Use during pregnancy may harm the baby. [1] It is a alkylating agent. [1]
Streptozotocin was approved for medical use in the United States in 1982. [1] In the United Kingdom it cost the NHS about £570 per 1 gram as of 2021. [2] This amount in the United States costs about 370 USD. [3] It is sold under the brand name Zanosar among others. [1]
{{
cite book}}
: CS1 maint: date format (
link)