From Wikipedia, the free encyclopedia
Mr. Ibrahem/Precipitated sulfur
Clinical data
Other namesMilk of sulfur; [1] sulfur praecipitatum; sulphur precipitated in petroleum jelly
AHFS/ Drugs.com Multum Consumer Information
Routes of
administration
Topical, rarely by mouth
Legal status
Legal status
Identifiers
  • Octathiocane
Chemical and physical data
FormulaS8
Molar mass256.48 g·mol−1
3D model ( JSmol)
  • S1SSSSSSS1
  • InChI=1S/S8/c1-2-4-6-8-7-5-3-1
  • Key:JLQNHALFVCURHW-UHFFFAOYSA-N

Precipitated sulfur is used as a medication to treat scabies and lice; including head, body, and pubic lice. [3] Other uses include acne, rosacea, tinea, warts, and seborrheic dermatitis. [2] [1] It is applied to the skin. [4]

Side effects include the fact that it smells unpleasant possibility contact dermatitis. [1] Use appears safe during pregnancy and breastfeeding, except around the breast. [5] [1] It may be better tolerated than benzoyl peroxide. [1] It acts as a keratolytic agent and also kills bacteria, parasites, and fungi. [2] [1] Chemically, it is the naturally occurring octasulfur (S8). [6]

Sulfur has a history of medical use going back to at least the time of Hippocrates. [1] While not officially approved for a specific medical use in the United States, it is avaliable over the counter as of 2020. [2] It is approved for use in Saudi Arabia. [2] It is on the World Health Organization's List of Essential Medicines as an alternative to benzyl benzoate. [4] It may also be compounded by a pharmacy. [7] It is generally not expensive. [8] In medicine it is the most commonly used form of sulfur. [9]

References

  1. ^ a b c d e f g h i Wolverton, Stephen E.; Wu, Jashin J. (14 December 2019). Comprehensive Dermatologic Drug Therapy. Elsevier Health Sciences. p. 611. ISBN  978-0-323-61212-8. Archived from the original on 16 December 2023. Retrieved 15 December 2023.
  2. ^ a b c d e Yuen, Melissa (2020). "Precipitated Sulfur: Summary Report" (PDF). Archived (PDF) from the original on 16 December 2023. Retrieved 15 December 2023.
  3. ^ a b "eEML - Electronic Essential Medicines List". list.essentialmeds.org. Archived from the original on 23 September 2023. Retrieved 15 December 2023.
  4. ^ a b World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl: 10665/371090. WHO/MHP/HPS/EML/2023.02.
  5. ^ "Sulfur". Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development. 2006. Archived from the original on 23 September 2023. Retrieved 15 December 2023.
  6. ^ Steudel, Ralf; Göbel, Thomas; Holdt, Gabriele (1 February 1988). "The Molecular Composition of Hydrophilic Sulfur Sols Prepared by Acid Decomposition of Thiosulfate [1]". Zeitschrift für Naturforschung B. 43 (2): 203–218. doi: 10.1515/znb-1988-0212.
  7. ^ Chiu, S; Argaez, C (16 May 2019). "Ivermectin for Parasitic Skin Infections of Scabies: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines". CADTH Rapid Response Reports. PMID  31424718.
  8. ^ "Scabies Medication: Antiparasitic Agents, Topical Antibiotics, Corticosteroids, Topical". emedicine.medscape.com. Archived from the original on 29 November 2023. Retrieved 15 December 2023.
  9. ^ MD, Stephen E. Wolverton (16 November 2012). Comprehensive Dermatologic Drug Therapy: Expert Consult - Online and Print. Elsevier Health Sciences. p. 599. ISBN  978-1-4377-2003-7. Archived from the original on 16 December 2023. Retrieved 15 December 2023.
From Wikipedia, the free encyclopedia
Mr. Ibrahem/Precipitated sulfur
Clinical data
Other namesMilk of sulfur; [1] sulfur praecipitatum; sulphur precipitated in petroleum jelly
AHFS/ Drugs.com Multum Consumer Information
Routes of
administration
Topical, rarely by mouth
Legal status
Legal status
Identifiers
  • Octathiocane
Chemical and physical data
FormulaS8
Molar mass256.48 g·mol−1
3D model ( JSmol)
  • S1SSSSSSS1
  • InChI=1S/S8/c1-2-4-6-8-7-5-3-1
  • Key:JLQNHALFVCURHW-UHFFFAOYSA-N

Precipitated sulfur is used as a medication to treat scabies and lice; including head, body, and pubic lice. [3] Other uses include acne, rosacea, tinea, warts, and seborrheic dermatitis. [2] [1] It is applied to the skin. [4]

Side effects include the fact that it smells unpleasant possibility contact dermatitis. [1] Use appears safe during pregnancy and breastfeeding, except around the breast. [5] [1] It may be better tolerated than benzoyl peroxide. [1] It acts as a keratolytic agent and also kills bacteria, parasites, and fungi. [2] [1] Chemically, it is the naturally occurring octasulfur (S8). [6]

Sulfur has a history of medical use going back to at least the time of Hippocrates. [1] While not officially approved for a specific medical use in the United States, it is avaliable over the counter as of 2020. [2] It is approved for use in Saudi Arabia. [2] It is on the World Health Organization's List of Essential Medicines as an alternative to benzyl benzoate. [4] It may also be compounded by a pharmacy. [7] It is generally not expensive. [8] In medicine it is the most commonly used form of sulfur. [9]

References

  1. ^ a b c d e f g h i Wolverton, Stephen E.; Wu, Jashin J. (14 December 2019). Comprehensive Dermatologic Drug Therapy. Elsevier Health Sciences. p. 611. ISBN  978-0-323-61212-8. Archived from the original on 16 December 2023. Retrieved 15 December 2023.
  2. ^ a b c d e Yuen, Melissa (2020). "Precipitated Sulfur: Summary Report" (PDF). Archived (PDF) from the original on 16 December 2023. Retrieved 15 December 2023.
  3. ^ a b "eEML - Electronic Essential Medicines List". list.essentialmeds.org. Archived from the original on 23 September 2023. Retrieved 15 December 2023.
  4. ^ a b World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl: 10665/371090. WHO/MHP/HPS/EML/2023.02.
  5. ^ "Sulfur". Drugs and Lactation Database (LactMed®). National Institute of Child Health and Human Development. 2006. Archived from the original on 23 September 2023. Retrieved 15 December 2023.
  6. ^ Steudel, Ralf; Göbel, Thomas; Holdt, Gabriele (1 February 1988). "The Molecular Composition of Hydrophilic Sulfur Sols Prepared by Acid Decomposition of Thiosulfate [1]". Zeitschrift für Naturforschung B. 43 (2): 203–218. doi: 10.1515/znb-1988-0212.
  7. ^ Chiu, S; Argaez, C (16 May 2019). "Ivermectin for Parasitic Skin Infections of Scabies: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines". CADTH Rapid Response Reports. PMID  31424718.
  8. ^ "Scabies Medication: Antiparasitic Agents, Topical Antibiotics, Corticosteroids, Topical". emedicine.medscape.com. Archived from the original on 29 November 2023. Retrieved 15 December 2023.
  9. ^ MD, Stephen E. Wolverton (16 November 2012). Comprehensive Dermatologic Drug Therapy: Expert Consult - Online and Print. Elsevier Health Sciences. p. 599. ISBN  978-1-4377-2003-7. Archived from the original on 16 December 2023. Retrieved 15 December 2023.

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