![]() Complex of lipase with
colipase | |
Clinical data | |
---|---|
Trade names | Creon, Pancreaze, Pancrex, others |
AHFS/ Drugs.com | Monograph |
MedlinePlus | a604035 |
Pregnancy category |
|
Routes of administration | By mouth |
Pancreatic enzymes, also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. [1] [3] They are used to treat malabsorption syndrome due to certain pancreatic problems. [1] These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long term pancreatitis, or pancreatic cancer, among others. [1] [4] The preparation is taken by mouth. [1]
Common side effects include vomiting, abdominal pain, constipation, and diarrhea. [1] Other side effects include perianal irritation and high blood uric acid. [4] The enzymes are from pigs. [4] Use is believed to be safe during pregnancy. [4] The components are digestive enzymes similar to those normally produced by the human pancreas. [5] They help the person digest fats, starches, and proteins. [4]
Pancreatic enzymes have been used as medications since at least the 1800s. [6] They are on the World Health Organization's List of Essential Medicines. [7] In the United Kingdom a typical month's supply costs the NHS about £12.93 to £47.55 as of 2019. [8] In the United States the wholesale cost of this amount is about US$300 to US$900. [9] In 2017, it was the 275th most commonly prescribed medication in the United States, with more than one million prescriptions. [10] [11]
![]() Complex of lipase with
colipase | |
Clinical data | |
---|---|
Trade names | Creon, Pancreaze, Pancrex, others |
AHFS/ Drugs.com | Monograph |
MedlinePlus | a604035 |
Pregnancy category |
|
Routes of administration | By mouth |
Pancreatic enzymes, also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. [1] [3] They are used to treat malabsorption syndrome due to certain pancreatic problems. [1] These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long term pancreatitis, or pancreatic cancer, among others. [1] [4] The preparation is taken by mouth. [1]
Common side effects include vomiting, abdominal pain, constipation, and diarrhea. [1] Other side effects include perianal irritation and high blood uric acid. [4] The enzymes are from pigs. [4] Use is believed to be safe during pregnancy. [4] The components are digestive enzymes similar to those normally produced by the human pancreas. [5] They help the person digest fats, starches, and proteins. [4]
Pancreatic enzymes have been used as medications since at least the 1800s. [6] They are on the World Health Organization's List of Essential Medicines. [7] In the United Kingdom a typical month's supply costs the NHS about £12.93 to £47.55 as of 2019. [8] In the United States the wholesale cost of this amount is about US$300 to US$900. [9] In 2017, it was the 275th most commonly prescribed medication in the United States, with more than one million prescriptions. [10] [11]