 | |
 | |
| Clinical data | |
|---|---|
| Trade names | Amerge, Naramig, others |
| AHFS/ Drugs.com | Monograph |
| MedlinePlus | a601083 |
|
Pregnancy category |
|
|
Routes of administration | By mouth |
| Drug class | Triptan [1] |
| Legal status | |
| Legal status |
|
| Pharmacokinetic data | |
| Bioavailability | 74% |
| Metabolism | Liver |
| Elimination half-life | 5-8 hours |
| Excretion | Kidney |
| Identifiers | |
| |
| Chemical and physical data | |
| Formula | C17H25N3O2S |
| Molar mass | 335.47 g·mol−1 |
| 3D model ( JSmol) | |
| |
| |
| (verify) | |
Naratriptan, sold under the brand name Amerge among others, is a medication used to treat migraine headaches. [1] It is not used preventatively. [1] It is taken by mouth. [1]
Common side effects include numbness, nausea, sleepiness, and tiredness. [1] Other side effects may include coronary vasospasm, stroke, high blood pressure, serotonin syndrome, anaphylaxis, and medication overuse headache. [1] Safety in pregnancy is unclear. [3] It is a triptan which works as a selective 5-HT1 receptor agonist. [1]
Naratriptan was patented in 1987 and approved for medical use in 1997. [4] It is available as a generic medication. [2] In the United Kingdom 6 tablets costs the NHS about £3 as of 2021. [2] This amount in the United States is about 11 USD. [5]
References
- ^ a b c d e f g h i "Naratriptan Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 11 November 2021.
- ^ a b c BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 501. ISBN 978-0857114105.
- ^ "Naratriptan (Amerge) Use During Pregnancy". Drugs.com. Archived from the original on 25 November 2020. Retrieved 12 November 2021.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 531. ISBN 978-3-527-60749-5. Archived from the original on 2020-10-23. Retrieved 2021-10-24.
- ^ "Naratriptan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 31 October 2016. Retrieved 11 November 2021.
|
| |
|
| |
| Clinical data | |
|---|---|
| Trade names | Amerge, Naramig, others |
| AHFS/ Drugs.com | Monograph |
| MedlinePlus | a601083 |
|
Pregnancy category |
|
|
Routes of administration | By mouth |
| Drug class | Triptan [1] |
| Legal status | |
| Legal status |
|
| Pharmacokinetic data | |
| Bioavailability | 74% |
| Metabolism | Liver |
| Elimination half-life | 5-8 hours |
| Excretion | Kidney |
| Identifiers | |
| |
| Chemical and physical data | |
| Formula | C17H25N3O2S |
| Molar mass | 335.47 g·mol−1 |
| 3D model ( JSmol) | |
| |
| |
| (verify) | |
Naratriptan, sold under the brand name Amerge among others, is a medication used to treat migraine headaches. [1] It is not used preventatively. [1] It is taken by mouth. [1]
Common side effects include numbness, nausea, sleepiness, and tiredness. [1] Other side effects may include coronary vasospasm, stroke, high blood pressure, serotonin syndrome, anaphylaxis, and medication overuse headache. [1] Safety in pregnancy is unclear. [3] It is a triptan which works as a selective 5-HT1 receptor agonist. [1]
Naratriptan was patented in 1987 and approved for medical use in 1997. [4] It is available as a generic medication. [2] In the United Kingdom 6 tablets costs the NHS about £3 as of 2021. [2] This amount in the United States is about 11 USD. [5]
References
- ^ a b c d e f g h i "Naratriptan Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 11 November 2021.
- ^ a b c BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 501. ISBN 978-0857114105.
- ^ "Naratriptan (Amerge) Use During Pregnancy". Drugs.com. Archived from the original on 25 November 2020. Retrieved 12 November 2021.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 531. ISBN 978-3-527-60749-5. Archived from the original on 2020-10-23. Retrieved 2021-10-24.
- ^ "Naratriptan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 31 October 2016. Retrieved 11 November 2021.