![]() | |
![]() | |
Clinical data | |
---|---|
Pronunciation | /ˈhɛpərɪn/ HEP-ər-in |
AHFS/ Drugs.com | Monograph |
Pregnancy category |
|
Routes of administration | IV, SQ |
Legal status | |
Legal status |
|
Pharmacokinetic data | |
Bioavailability | Erratic |
Metabolism | Liver |
Elimination half-life | 1.5 hours |
Excretion | Urine [2] |
Identifiers | |
Chemical and physical data | |
Formula | C12H19NO20S3 |
Molar mass | 12000–15000 g/mol g·mol−1 |
| |
![]() ![]() |
Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. [4] [6] As a medication it is used as an anticoagulant (blood thinner). [4] Specifically it is used in the treatment of heart attacks, unstable angina, and to prevent and treat blood clots in either veins or arteries. [4] [3] It is given by injection into a vein or under the skin. [4] Other uses include inside test tubes and kidney dialysis machines. [6] [7]
Common side effects include bleeding, pain at the injection site, and low blood platelets. [4] Serious side effects include heparin-induced thrombocytopenia. [4] Greater care is needed in those with poor kidney function. [4] Heparin appears to be relatively safe for use during pregnancy and breastfeeding. [8] Heparin is produced by basophils and mast cells in all mammals. [9]
The discovery of heparin was announced in 1916. [10] It is on the World Health Organization's List of Essential Medicines. [11] The wholesale cost in the developing world, when used for prevention, is about US$9.63–37.95 per month. [12] In the United States it costs about $25–50 per month. [13] A fractionated version of heparin, known as low molecular weight heparin, is also available. [14]
MSF2020
was invoked but never defined (see the
help page).WHO2020DDD
was invoked but never defined (see the
help page).
![]() | |
![]() | |
Clinical data | |
---|---|
Pronunciation | /ˈhɛpərɪn/ HEP-ər-in |
AHFS/ Drugs.com | Monograph |
Pregnancy category |
|
Routes of administration | IV, SQ |
Legal status | |
Legal status |
|
Pharmacokinetic data | |
Bioavailability | Erratic |
Metabolism | Liver |
Elimination half-life | 1.5 hours |
Excretion | Urine [2] |
Identifiers | |
Chemical and physical data | |
Formula | C12H19NO20S3 |
Molar mass | 12000–15000 g/mol g·mol−1 |
| |
![]() ![]() |
Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. [4] [6] As a medication it is used as an anticoagulant (blood thinner). [4] Specifically it is used in the treatment of heart attacks, unstable angina, and to prevent and treat blood clots in either veins or arteries. [4] [3] It is given by injection into a vein or under the skin. [4] Other uses include inside test tubes and kidney dialysis machines. [6] [7]
Common side effects include bleeding, pain at the injection site, and low blood platelets. [4] Serious side effects include heparin-induced thrombocytopenia. [4] Greater care is needed in those with poor kidney function. [4] Heparin appears to be relatively safe for use during pregnancy and breastfeeding. [8] Heparin is produced by basophils and mast cells in all mammals. [9]
The discovery of heparin was announced in 1916. [10] It is on the World Health Organization's List of Essential Medicines. [11] The wholesale cost in the developing world, when used for prevention, is about US$9.63–37.95 per month. [12] In the United States it costs about $25–50 per month. [13] A fractionated version of heparin, known as low molecular weight heparin, is also available. [14]
MSF2020
was invoked but never defined (see the
help page).WHO2020DDD
was invoked but never defined (see the
help page).