USER:MR. IBRAHEM CARBACHOL

Mr. Ibrahem/Carbachol
Clinical data
Trade names	Miostat, others
Other names	Carbamylcholine
AHFS/ Drugs.com	Monograph
License data	US DailyMed: Carbachol;
Pregnancy; category	AU: B2; ;
Routes of; administration	By mouth ( tablets); Solution for injection; Eye drop
Drug class	Cholinergic agonist
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	Low
Identifiers
	IUPAC name 2-[(Aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride;
Chemical and physical data
Formula	C6H15ClN2O2
Molar mass	182.65 g·mol−1
3D model ( JSmol)	Interactive image;
	SMILES [Cl-].O=C(OCC[N+](C)(C)C)N;
	InChI InChI=1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H ; Key:AIXAANGOTKPUOY-UHFFFAOYSA-N ;
	(verify)

Carbachol, sold under the brand name Miostat among others, is a medication used to treat glaucoma or during eye surgery.^[1] Usually other agents such as pilocarpine or acetylcholine preferred.^[1] It is used as an eye drop or injected into the eye.^[1]

Common side effects include eye discomfort, headache, blurry vision, trouble seeing in low light, and red eyes.^[1] Other side effects may include allergic reactions, retinal detachment, diarrhea, low blood pressure, sweating, and arrhythmias.^[1] Safety in pregnancy is unclear.^[1] It is a cholinergic agonist that binds and activates acetylcholine receptors.^[1]

Carbachol was approved for medical use in the United States in 1972.^[1] It is on the World Health Organization's List of Essential Medicines as an alternative to pilocarpine.^[2] In the United States the solution for injection into the eye costs about 27 USD per dose as of 2021.^[3]

References

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k "Carbachol Monograph for Professionals". Drugs.com. Archived from the original on 29 April 2021. Retrieved 29 December 2021.
^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl: 10665/345533. WHO/MHP/HPS/EML/2021.02.
^ "Miostat Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 17 January 2021. Retrieved 29 December 2021.