Code | Chemical name | h5-HT2A Ki / EC50 (nM) | Dose (mg) | PubChem | CAS number | Reference |
---|---|---|---|---|---|---|
AEM | 1-(3,4,5-trimethoxyphenyl)butan-2-amine | 204932 | 17097-73-3 | [1] | ||
BOH | 1-(3,4-methylenedioxyphenyl)-1-methoxy-2-aminoethane | 44719487 | 73304-06-0 | PIHKAL | ||
BOM | 2-methoxy-2-(3,4,5-trimethoxyphenyl)ethanamine | 98537-40-7 | PIHKAL | |||
BOD | 2-(2,5-dimethoxy-4-methylphenyl)-2-methoxyethanamine | 98537-41-8 | PIHKAL | |||
BOB | 2-(4-bromo-2,5-dimethoxyphenyl)-2-methoxyethanamine | 98537-42-9 | PIHKAL | |||
Mescaline | 2-(3,4,5-trimethoxyphenyl)ethanamine | 551 (vs 125I DOI) | 180-360 | 4076 | 54-04-6 | PIHKAL |
Escaline | 2-(4-ethoxy-3,5-dimethoxyphenyl)ethanamine | 215 | 40-60 | 38240 | 39201-82-6 | PIHKAL |
Proscaline | 2-(3,5-dimethoxy-4-propoxyphenyl)ethanamine | 30-60 | 39201-78-0 | PIHKAL | ||
Alscaline | 2-(4-allyloxy-3,5-dimethoxyphenyl)ethanamine | 20-35 | 39201-75-7 | PIHKAL | ||
Isoproscaline | 2-(4-isopropoxy-3,5-dimethoxyphenyl)ethanamine | 465 | 40-80 | 64778-72-9 | PIHKAL | |
Buscaline | 2-(3,5-dimethoxy-4-butoxyphenyl)ethanamine | 150+ | 64778-75-2 | PIHKAL | ||
Methallylescaline | 2-(3,5-dimethoxy-4-[(2-methylprop-2-en-1-yl)oxy]phenyl)ethanamine | 40-65 | 207740-41-8 | PIHKAL | ||
Metaescaline | 2-(3-ethoxy-4,5-dimethoxyphenyl)ethanamine | 90132-31-3 | PIHKAL | |||
Lophophine | 2-(3-methoxy-4,5-methylenedioxyphenyl)ethanamine | 90239 | 23693-38-1 | PIHKAL | ||
Macromerine | 1-(3,4-dimethoxyphenyl)-2-(dimethylamino)ethanol | 165055 | 2970-95-8 | |||
Difluoromescaline | 2-[4-(difluoromethoxy)-3,5-dimethoxyphenyl]ethanamine | 50-100 | 1178367-63-9 | [2] | ||
Difluoroescaline | 1-[4-(2,2-difluoroethoxy)-3,5-dimethoxyphenyl]-2-aminoethane | 40-80 | 501700-02-3 | Phenethylamine Von der Struktur zur Funktion | ||
Trifluoroescaline | 1-[4-(2,2,2-trifluoroethoxy)-3,5-dimethoxyphenyl]-2-aminoethane | 35-65 | 501700-03-4 | Phenethylamine Von der Struktur zur Funktion | ||
Fluoroproscaline | 1-[4-(3-fluoropropoxy)-3,5-dimethoxyphenyl]-2-aminoethane | 60-150 | 501700-04-5 | Phenethylamine Von der Struktur zur Funktion | ||
Jimscaline | (R)-(2,3-dihydro-4,5,6-trimethoxy-1H-inden-1-yl)aminomethane | 69 (rat) / 3200 | 11673493 | 890309-57-6 | [3] | |
Juncosamine | (2S,6S)-2-(2,5-dimethoxy-4-bromobenzyl)-6-(2-methoxyphenyl)piperidine | 1391499-52-7 | [4] | |||
3TM | 2-(3-methylthio-4,5-dimethoxyphenyl)ethanamine | 60-100 | PIHKAL | |||
4TM | 2-(3,5-dimethoxy-4-methylthiophenyl)ethanamine | 20-40 | 71539-35-0 | PIHKAL | ||
3TE | 2-(3-methylthio-4-ethoxy-5-methoxyphenyl)ethanamine | 60-80 | PIHKAL | |||
4TE | 2-(3,5-dimethoxy-4-ethylthiophenyl)ethanamine | 20-30 | 90109-49-2 | PIHKAL | ||
4TP | 2-(3,5-dimethoxy-4-propylthiophenyl)ethanamine | 20-25 | 90109-55-0 | PIHKAL | ||
4TB | 2-(4-butylthio-3,5-dimethoxyphenyl)ethanamine | 60-120 | 90109-57-2 | PIHKAL | ||
2,5-DMA | 2,5-dimethoxyamphetamine | 2801-68-5 | ||||
3,4-DMA | 3,4-dimethoxyamphetamine | 120-26-3 | ||||
2,4-DMA | 2,4-dimethoxyamphetamine | 23690-13-3 | ||||
3,5-DMA | 3,5-dimethoxyamphetamine | 15402-82-1 | ||||
2,6-DMA | 2,6-dimethoxyamphetamine | 23690-14-4 | ||||
4-EtO-2,5-DMA | 4-ethoxy-2,5-dimethoxyamphetamine | 16128-88-4 | ||||
2-EtO-4,5-DMA | 2-ethoxy-4,5-dimethoxyamphetamine | 23693-30-3 | ||||
5-EtO-2,4-DMA | 5-ethoxy-2,4-dimethoxyamphetamine | 23693-32-5 | ||||
2,4-diEtO-5-MeO-amphetamine | 2,4-diethoxy-5-methoxyamphetamine | 23693-33-6 | ||||
2,5-diEtO-4-MeO-amphetamine | 2,5-diethoxy-4-methoxyamphetamine | 23693-34-7 | ||||
2-MeO-4,5-diEtO-amphetamine | 2-methoxy-4,5-diethoxyamphetamine | 23693-35-8 | ||||
2,4,5-triEtO-amphetamine | 2,4,5-triethoxyamphetamine | 23693-42-7 | ||||
2,3,4-TMA | 2,3,4-trimethoxyamphetamine | 1082-23-1 | ||||
2,4,5-TMA | 2,4,5-trimethoxyamphetamine | 1083-09-6 | ||||
3,4,5-TMA | 3,4,5-trimethoxyamphetamine | 1082-88-8 | ||||
2,4,6-TMA | 2,4,6-trimethoxyamphetamine | 15402-79-6 | ||||
2,3,5-TMA | 2,3,5-trimethoxyamphetamine | 23693-14-3 | ||||
2,3,6-TMA | 2,3,6-trimethoxyamphetamine | 20513-16-0 | ||||
1-(5,8-dimethoxy-3,4-dihydro-1H-isochromen-7-yl)isopropanamine | 774538-38-4 | |||||
AOMA | 3-methoxy-4-allyloxyamphetamine | 1178502-18-5 | ||||
BOMA | 3-methoxy-4-benzyloxyamphetamine | 114963-05-2 | ||||
POMA | 3-methoxy-4-propoxyamphetamine | 910407-76-0 | ||||
DOM | 2,5-dimethoxy-4-methylamphetamine | 15588-95-1 | ||||
Ψ-DOM | 2,6-dimethoxy-4-methylamphetamine | 80888-36-4 | ||||
DOET | 2,5-dimethoxy-4-ethylamphetamine | 22004-32-6 | ||||
DOEF | 2,5-dimethoxy-4-(2-fluoroethyl)amphetamine | 121649-01-2 | ||||
DOPR | 2,5-dimethoxy-4-propylamphetamine | 63779-88-4 | ||||
DOBU | 2,5-dimethoxy-4-butylamphetamine | 63779-89-5 | ||||
DOF | 2,5-dimethoxy-4-fluoroamphetamine | 125903-69-7 | ||||
DOC | 2,5-dimethoxy-4-chloroamphetamine | 123431-31-2 | ||||
DOB | 2,5-dimethoxy-4-bromoamphetamine | 32156-26-6 or 64638-07-9 | ||||
N-Me-DOB | N-methyl-2,5-dimethoxy-4-bromoamphetamine | 155638-80-5 | ||||
4C-DOB | 1-(2,5-dimethoxy-4-bromophenyl)butan-2-amine | 69294-23-1 | ||||
4C-DOM | 1-(2,5-dimethoxy-4-methylphenyl)butan-2-amine | 52663-86-2 or 52842-59-8 or 52842-58-7 | ||||
4C-DOC | 1-(2,5-dimethoxy-4-chlorophenyl)butan-2-amine | 791010-74-7 | ||||
4C-DOI | 1-(2,5-dimethoxy-4-iodophenyl)butan-2-amine | 758631-75-3 | ||||
4C-DON | 1-(2,5-dimethoxy-4-nitrophenyl)butan-2-amine | 775234-58-7 | ||||
4-Br-3,5-DMA | 3,5-dimethoxy-4-bromoamphetamine | 32156-34-6 or 64778-79-6 (R) | ||||
4-PP-3,5-DMA | 3,5-dimethoxy-4-(3-phenylpropyl)amphetamine | 785765-10-8 | [5] | |||
DOI | 2,5-dimethoxy-4-iodoamphetamine | 64584-34-5 or 82830-44-2 or 82830-53-3 | ||||
DON | 2,5-dimethoxy-4-nitroamphetamine | 67460-68-8 | ||||
DOTFM | 2,5-dimethoxy-4-(trifluoromethyl)amphetamine | 159277-07-3 | ||||
DOYN | 2,5-dimethoxy-4-ethynylamphetamine | 633290-70-7 | ||||
DODC | 2,5-dimethoxy-3,4-dichloroamphetamine | 1373918-65-0 | ||||
DOBn | 2,5-dimethoxy-4-benzylamphetamine | 125903-73-3 | ||||
DOTh | 2,5-dimethoxy-4-[(thiophen-2-yl)methyl]amphetamine | 930776-29-7 | ||||
DO(3-MeOBn) | 2,5-dimethoxy-4-(3-methoxybenzyl)amphetamine | 930836-90-1 | ||||
DOMOM | 2,5-dimethoxy-4-(methoxymethyl)amphetamine | 260810-10-4 | ||||
DOMOE | 2,5-dimethoxy-4-(ethoxymethyl)amphetamine | 930836-81-0 | ||||
DOTHFM | 2,5-dimethoxy-4-[(tetrahydrofuran-2-yl)methyl]amphetamine | 930776-12-8 | ||||
ALEPH | 2,5-dimethoxy-4-(methylthio)amphetamine | 61638-07-1 | ||||
ALEPH-2 | 2,5-dimethoxy-4-(ethylthio)amphetamine | 185562-00-9 | ||||
ALEPH-4 | 2,5-dimethoxy-4-(isopropylthio)amphetamine | 123643-26-5 | ||||
ALEPH-7 | 2,5-dimethoxy-4-(propylthio)amphetamine | 207740-16-7 | ||||
TOM-2 | 2-methylthio-4-methyl-5-methoxyamphetamine | 60-100 | 207740-44-1 | |||
TOM-5 | 2-methoxy-4-methyl-5-methylthioamphetamine | 30-50 | 207740-45-2 | |||
TOET-2 | 2-methylthio-4-ethyl-5-methoxyamphetamine | 84910-91-8 | ||||
TOET-5 | 2-methoxy-4-ethyl-5-methylthioamphetamine | 12-25 | 207740-43-0 | |||
TOMSO | 2-methoxy-4-methyl-5-methylsulfinylamphetamine | 100-150 | 84910-95-2 | |||
2C-B | 2,5-dimethoxy-4-bromophenethylamine | 66142-81-2 | PIHKAL | |||
β-Methyl-2CB | 2-(2,5-dimethoxy-4-bromophenyl)-1-aminopropane | 52432-70-9 | Phenethylamine Von der Struktur zur Funktion |
Structure | Name | Chemical name | h5-HT2A Ki (EC50) (nM) | PubChem | CAS number | Reference |
---|---|---|---|---|---|---|
Compound 23 | 9-Chloro-7-(2-ethoxy-phenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole | 32 | 44315398 | 599173-25-8 | [1] | |
Compound 10d | 7-Benzyloxy-8-bromo-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine | 22 | 10472780 | 616201-60-6 | [2] | |
Example 22.67 | 4-(6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepin-2-yl)thiomorpholine | 21 | 44124494 | [3] | ||
Compound 3d (N-Bn-THAZ) | 2-benzyl-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepin-3-one | (549) | 14515725 | 125115-66-4 | [4] | |
Example 1 ( ZC-B) | 3-(4-bromo-2,5-dimethoxyphenyl)azetidine | (1.6) | 156337249 | 2641630-65-9 | [5] | |
Compound 11 | (3R)-N,N-diethyl-5-(1H-indol-4-yl)-1-methyl-3,6-dihydro-2H-pyridine-3-carboxamide | (<10) | 156278040 | [6] | ||
Compound 106 | 6-chloro-1-(2,4,5-trimethoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole | 4376990 | 528525-37-3 | [7] | ||
Compound 6c | (6S)-2,3-dichloro-7,8,9,10-tetrahydro-6H-6,9-epiminocyclohepta[b]quinoxaline | (400) | [8] | |||
Efavirenz | (4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one | 64139 | 154598-52-4 | [9] | ||
IHCH-7113 | (6bR,10aS)-3-methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline | 21302499 | 313368-85-3 | [10] | ||
Mefloquine | 2,8-bis(trifluoromethyl)quinolin-4-yl-(2-piperidyl)methanol | 40692 | 53230-10-7 | [11] | ||
ORG-37684 | (3S)-3-[(2,3-dihydro-5-methoxy-1H-inden-4-yl)oxy]pyrrolidine | 9794656 | 213007-95-5 | [12] | ||
P-54 | 2-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-N,N-dimethylethanamine | 168946740 | [13] | |||
(R)-69 | 3-[(5R)-5-methyl-1,2,5,6-tetrahydropyridin-3-yl]-1H-pyrrolo[2,3-b]pyridine | 164513426 | [14] | |||
RH-34 | 3-[2-(2-methoxybenzylamino)ethyl]-1H-quinazoline-2,4-dione | 10041987 | 1028307-48-3 | [15] | ||
SCHEMBL5334361 | 7-[(3-methoxyphenoxy)methyl]-2,3,4,5-tetrahydro-1H-3-benzazepine | (0.4) | 59027940 | 959867-47-1 | [16] | |
WXVL_BT0793LQ2118 | 6-fluoro-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1H-indole | [17] | ||||
Z2825713589 | (4-amino-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-(6-methoxypyrazin-2-yl)methanone | 167788805 | [17] | |||
Z2876442907 | ethyl 2-[[2-(4-methyl-1H-indol-3-yl)ethylamino]methyl]-1,3-thiazole-5-carboxylate | 167850865 | [17] | |||
Z3517967757 | 4-[1-(1-pyrimidin-2-ylethyl)piperidin-3-yl]phenol | 167949972 | [17] | |||
Z3881312504 | 2-bromo-4-[2-[methyl-[2-(1,3-thiazol-2-yl)ethyl]amino]ethyl]phenol | 167904469 | [17] | |||
Z4154032166 | 2,2,2-trifluoro-1-[6-(1,2,3,6-tetrahydropyridin-5-yl)pyridin-2-yl]ethanol | 167878716 | [17] | |||
Z5247692566 | 4-[(3,3-dimethyloxolan-2-yl)methyl]-3-[(1H-indol-3-yl)methyl]morpholine | [17] | ||||
Z5247692629 | 1-(1-bicyclo[1.1.1]pentanyl)-4-[[5-(4-chlorophenyl)-1H-pyrazol-4-yl]methyl]piperazine | 166358273 | [17] |
Code | Chemical name | h5-HT2A Ki / EC50 (nM) | Dose (mg) | PubChem | CAS number | Reference |
---|---|---|---|---|---|---|
AEM | 1-(3,4,5-trimethoxyphenyl)butan-2-amine | 204932 | 17097-73-3 | [1] | ||
BOH | 1-(3,4-methylenedioxyphenyl)-1-methoxy-2-aminoethane | 44719487 | 73304-06-0 | PIHKAL | ||
BOM | 2-methoxy-2-(3,4,5-trimethoxyphenyl)ethanamine | 98537-40-7 | PIHKAL | |||
BOD | 2-(2,5-dimethoxy-4-methylphenyl)-2-methoxyethanamine | 98537-41-8 | PIHKAL | |||
BOB | 2-(4-bromo-2,5-dimethoxyphenyl)-2-methoxyethanamine | 98537-42-9 | PIHKAL | |||
Mescaline | 2-(3,4,5-trimethoxyphenyl)ethanamine | 551 (vs 125I DOI) | 180-360 | 4076 | 54-04-6 | PIHKAL |
Escaline | 2-(4-ethoxy-3,5-dimethoxyphenyl)ethanamine | 215 | 40-60 | 38240 | 39201-82-6 | PIHKAL |
Proscaline | 2-(3,5-dimethoxy-4-propoxyphenyl)ethanamine | 30-60 | 39201-78-0 | PIHKAL | ||
Alscaline | 2-(4-allyloxy-3,5-dimethoxyphenyl)ethanamine | 20-35 | 39201-75-7 | PIHKAL | ||
Isoproscaline | 2-(4-isopropoxy-3,5-dimethoxyphenyl)ethanamine | 465 | 40-80 | 64778-72-9 | PIHKAL | |
Buscaline | 2-(3,5-dimethoxy-4-butoxyphenyl)ethanamine | 150+ | 64778-75-2 | PIHKAL | ||
Methallylescaline | 2-(3,5-dimethoxy-4-[(2-methylprop-2-en-1-yl)oxy]phenyl)ethanamine | 40-65 | 207740-41-8 | PIHKAL | ||
Metaescaline | 2-(3-ethoxy-4,5-dimethoxyphenyl)ethanamine | 90132-31-3 | PIHKAL | |||
Lophophine | 2-(3-methoxy-4,5-methylenedioxyphenyl)ethanamine | 90239 | 23693-38-1 | PIHKAL | ||
Macromerine | 1-(3,4-dimethoxyphenyl)-2-(dimethylamino)ethanol | 165055 | 2970-95-8 | |||
Difluoromescaline | 2-[4-(difluoromethoxy)-3,5-dimethoxyphenyl]ethanamine | 50-100 | 1178367-63-9 | [2] | ||
Difluoroescaline | 1-[4-(2,2-difluoroethoxy)-3,5-dimethoxyphenyl]-2-aminoethane | 40-80 | 501700-02-3 | Phenethylamine Von der Struktur zur Funktion | ||
Trifluoroescaline | 1-[4-(2,2,2-trifluoroethoxy)-3,5-dimethoxyphenyl]-2-aminoethane | 35-65 | 501700-03-4 | Phenethylamine Von der Struktur zur Funktion | ||
Fluoroproscaline | 1-[4-(3-fluoropropoxy)-3,5-dimethoxyphenyl]-2-aminoethane | 60-150 | 501700-04-5 | Phenethylamine Von der Struktur zur Funktion | ||
Jimscaline | (R)-(2,3-dihydro-4,5,6-trimethoxy-1H-inden-1-yl)aminomethane | 69 (rat) / 3200 | 11673493 | 890309-57-6 | [3] | |
Juncosamine | (2S,6S)-2-(2,5-dimethoxy-4-bromobenzyl)-6-(2-methoxyphenyl)piperidine | 1391499-52-7 | [4] | |||
3TM | 2-(3-methylthio-4,5-dimethoxyphenyl)ethanamine | 60-100 | PIHKAL | |||
4TM | 2-(3,5-dimethoxy-4-methylthiophenyl)ethanamine | 20-40 | 71539-35-0 | PIHKAL | ||
3TE | 2-(3-methylthio-4-ethoxy-5-methoxyphenyl)ethanamine | 60-80 | PIHKAL | |||
4TE | 2-(3,5-dimethoxy-4-ethylthiophenyl)ethanamine | 20-30 | 90109-49-2 | PIHKAL | ||
4TP | 2-(3,5-dimethoxy-4-propylthiophenyl)ethanamine | 20-25 | 90109-55-0 | PIHKAL | ||
4TB | 2-(4-butylthio-3,5-dimethoxyphenyl)ethanamine | 60-120 | 90109-57-2 | PIHKAL | ||
2,5-DMA | 2,5-dimethoxyamphetamine | 2801-68-5 | ||||
3,4-DMA | 3,4-dimethoxyamphetamine | 120-26-3 | ||||
2,4-DMA | 2,4-dimethoxyamphetamine | 23690-13-3 | ||||
3,5-DMA | 3,5-dimethoxyamphetamine | 15402-82-1 | ||||
2,6-DMA | 2,6-dimethoxyamphetamine | 23690-14-4 | ||||
4-EtO-2,5-DMA | 4-ethoxy-2,5-dimethoxyamphetamine | 16128-88-4 | ||||
2-EtO-4,5-DMA | 2-ethoxy-4,5-dimethoxyamphetamine | 23693-30-3 | ||||
5-EtO-2,4-DMA | 5-ethoxy-2,4-dimethoxyamphetamine | 23693-32-5 | ||||
2,4-diEtO-5-MeO-amphetamine | 2,4-diethoxy-5-methoxyamphetamine | 23693-33-6 | ||||
2,5-diEtO-4-MeO-amphetamine | 2,5-diethoxy-4-methoxyamphetamine | 23693-34-7 | ||||
2-MeO-4,5-diEtO-amphetamine | 2-methoxy-4,5-diethoxyamphetamine | 23693-35-8 | ||||
2,4,5-triEtO-amphetamine | 2,4,5-triethoxyamphetamine | 23693-42-7 | ||||
2,3,4-TMA | 2,3,4-trimethoxyamphetamine | 1082-23-1 | ||||
2,4,5-TMA | 2,4,5-trimethoxyamphetamine | 1083-09-6 | ||||
3,4,5-TMA | 3,4,5-trimethoxyamphetamine | 1082-88-8 | ||||
2,4,6-TMA | 2,4,6-trimethoxyamphetamine | 15402-79-6 | ||||
2,3,5-TMA | 2,3,5-trimethoxyamphetamine | 23693-14-3 | ||||
2,3,6-TMA | 2,3,6-trimethoxyamphetamine | 20513-16-0 | ||||
1-(5,8-dimethoxy-3,4-dihydro-1H-isochromen-7-yl)isopropanamine | 774538-38-4 | |||||
AOMA | 3-methoxy-4-allyloxyamphetamine | 1178502-18-5 | ||||
BOMA | 3-methoxy-4-benzyloxyamphetamine | 114963-05-2 | ||||
POMA | 3-methoxy-4-propoxyamphetamine | 910407-76-0 | ||||
DOM | 2,5-dimethoxy-4-methylamphetamine | 15588-95-1 | ||||
Ψ-DOM | 2,6-dimethoxy-4-methylamphetamine | 80888-36-4 | ||||
DOET | 2,5-dimethoxy-4-ethylamphetamine | 22004-32-6 | ||||
DOEF | 2,5-dimethoxy-4-(2-fluoroethyl)amphetamine | 121649-01-2 | ||||
DOPR | 2,5-dimethoxy-4-propylamphetamine | 63779-88-4 | ||||
DOBU | 2,5-dimethoxy-4-butylamphetamine | 63779-89-5 | ||||
DOF | 2,5-dimethoxy-4-fluoroamphetamine | 125903-69-7 | ||||
DOC | 2,5-dimethoxy-4-chloroamphetamine | 123431-31-2 | ||||
DOB | 2,5-dimethoxy-4-bromoamphetamine | 32156-26-6 or 64638-07-9 | ||||
N-Me-DOB | N-methyl-2,5-dimethoxy-4-bromoamphetamine | 155638-80-5 | ||||
4C-DOB | 1-(2,5-dimethoxy-4-bromophenyl)butan-2-amine | 69294-23-1 | ||||
4C-DOM | 1-(2,5-dimethoxy-4-methylphenyl)butan-2-amine | 52663-86-2 or 52842-59-8 or 52842-58-7 | ||||
4C-DOC | 1-(2,5-dimethoxy-4-chlorophenyl)butan-2-amine | 791010-74-7 | ||||
4C-DOI | 1-(2,5-dimethoxy-4-iodophenyl)butan-2-amine | 758631-75-3 | ||||
4C-DON | 1-(2,5-dimethoxy-4-nitrophenyl)butan-2-amine | 775234-58-7 | ||||
4-Br-3,5-DMA | 3,5-dimethoxy-4-bromoamphetamine | 32156-34-6 or 64778-79-6 (R) | ||||
4-PP-3,5-DMA | 3,5-dimethoxy-4-(3-phenylpropyl)amphetamine | 785765-10-8 | [5] | |||
DOI | 2,5-dimethoxy-4-iodoamphetamine | 64584-34-5 or 82830-44-2 or 82830-53-3 | ||||
DON | 2,5-dimethoxy-4-nitroamphetamine | 67460-68-8 | ||||
DOTFM | 2,5-dimethoxy-4-(trifluoromethyl)amphetamine | 159277-07-3 | ||||
DOYN | 2,5-dimethoxy-4-ethynylamphetamine | 633290-70-7 | ||||
DODC | 2,5-dimethoxy-3,4-dichloroamphetamine | 1373918-65-0 | ||||
DOBn | 2,5-dimethoxy-4-benzylamphetamine | 125903-73-3 | ||||
DOTh | 2,5-dimethoxy-4-[(thiophen-2-yl)methyl]amphetamine | 930776-29-7 | ||||
DO(3-MeOBn) | 2,5-dimethoxy-4-(3-methoxybenzyl)amphetamine | 930836-90-1 | ||||
DOMOM | 2,5-dimethoxy-4-(methoxymethyl)amphetamine | 260810-10-4 | ||||
DOMOE | 2,5-dimethoxy-4-(ethoxymethyl)amphetamine | 930836-81-0 | ||||
DOTHFM | 2,5-dimethoxy-4-[(tetrahydrofuran-2-yl)methyl]amphetamine | 930776-12-8 | ||||
ALEPH | 2,5-dimethoxy-4-(methylthio)amphetamine | 61638-07-1 | ||||
ALEPH-2 | 2,5-dimethoxy-4-(ethylthio)amphetamine | 185562-00-9 | ||||
ALEPH-4 | 2,5-dimethoxy-4-(isopropylthio)amphetamine | 123643-26-5 | ||||
ALEPH-7 | 2,5-dimethoxy-4-(propylthio)amphetamine | 207740-16-7 | ||||
TOM-2 | 2-methylthio-4-methyl-5-methoxyamphetamine | 60-100 | 207740-44-1 | |||
TOM-5 | 2-methoxy-4-methyl-5-methylthioamphetamine | 30-50 | 207740-45-2 | |||
TOET-2 | 2-methylthio-4-ethyl-5-methoxyamphetamine | 84910-91-8 | ||||
TOET-5 | 2-methoxy-4-ethyl-5-methylthioamphetamine | 12-25 | 207740-43-0 | |||
TOMSO | 2-methoxy-4-methyl-5-methylsulfinylamphetamine | 100-150 | 84910-95-2 | |||
2C-B | 2,5-dimethoxy-4-bromophenethylamine | 66142-81-2 | PIHKAL | |||
β-Methyl-2CB | 2-(2,5-dimethoxy-4-bromophenyl)-1-aminopropane | 52432-70-9 | Phenethylamine Von der Struktur zur Funktion |
Structure | Name | Chemical name | h5-HT2A Ki (EC50) (nM) | PubChem | CAS number | Reference |
---|---|---|---|---|---|---|
Compound 23 | 9-Chloro-7-(2-ethoxy-phenyl)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole | 32 | 44315398 | 599173-25-8 | [1] | |
Compound 10d | 7-Benzyloxy-8-bromo-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine | 22 | 10472780 | 616201-60-6 | [2] | |
Example 22.67 | 4-(6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepin-2-yl)thiomorpholine | 21 | 44124494 | [3] | ||
Compound 3d (N-Bn-THAZ) | 2-benzyl-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepin-3-one | (549) | 14515725 | 125115-66-4 | [4] | |
Example 1 ( ZC-B) | 3-(4-bromo-2,5-dimethoxyphenyl)azetidine | (1.6) | 156337249 | 2641630-65-9 | [5] | |
Compound 11 | (3R)-N,N-diethyl-5-(1H-indol-4-yl)-1-methyl-3,6-dihydro-2H-pyridine-3-carboxamide | (<10) | 156278040 | [6] | ||
Compound 106 | 6-chloro-1-(2,4,5-trimethoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole | 4376990 | 528525-37-3 | [7] | ||
Compound 6c | (6S)-2,3-dichloro-7,8,9,10-tetrahydro-6H-6,9-epiminocyclohepta[b]quinoxaline | (400) | [8] | |||
Efavirenz | (4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one | 64139 | 154598-52-4 | [9] | ||
IHCH-7113 | (6bR,10aS)-3-methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline | 21302499 | 313368-85-3 | [10] | ||
Mefloquine | 2,8-bis(trifluoromethyl)quinolin-4-yl-(2-piperidyl)methanol | 40692 | 53230-10-7 | [11] | ||
ORG-37684 | (3S)-3-[(2,3-dihydro-5-methoxy-1H-inden-4-yl)oxy]pyrrolidine | 9794656 | 213007-95-5 | [12] | ||
P-54 | 2-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-N,N-dimethylethanamine | 168946740 | [13] | |||
(R)-69 | 3-[(5R)-5-methyl-1,2,5,6-tetrahydropyridin-3-yl]-1H-pyrrolo[2,3-b]pyridine | 164513426 | [14] | |||
RH-34 | 3-[2-(2-methoxybenzylamino)ethyl]-1H-quinazoline-2,4-dione | 10041987 | 1028307-48-3 | [15] | ||
SCHEMBL5334361 | 7-[(3-methoxyphenoxy)methyl]-2,3,4,5-tetrahydro-1H-3-benzazepine | (0.4) | 59027940 | 959867-47-1 | [16] | |
WXVL_BT0793LQ2118 | 6-fluoro-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1H-indole | [17] | ||||
Z2825713589 | (4-amino-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-(6-methoxypyrazin-2-yl)methanone | 167788805 | [17] | |||
Z2876442907 | ethyl 2-[[2-(4-methyl-1H-indol-3-yl)ethylamino]methyl]-1,3-thiazole-5-carboxylate | 167850865 | [17] | |||
Z3517967757 | 4-[1-(1-pyrimidin-2-ylethyl)piperidin-3-yl]phenol | 167949972 | [17] | |||
Z3881312504 | 2-bromo-4-[2-[methyl-[2-(1,3-thiazol-2-yl)ethyl]amino]ethyl]phenol | 167904469 | [17] | |||
Z4154032166 | 2,2,2-trifluoro-1-[6-(1,2,3,6-tetrahydropyridin-5-yl)pyridin-2-yl]ethanol | 167878716 | [17] | |||
Z5247692566 | 4-[(3,3-dimethyloxolan-2-yl)methyl]-3-[(1H-indol-3-yl)methyl]morpholine | [17] | ||||
Z5247692629 | 1-(1-bicyclo[1.1.1]pentanyl)-4-[[5-(4-chlorophenyl)-1H-pyrazol-4-yl]methyl]piperazine | 166358273 | [17] |