From Wikipedia, the free encyclopedia
Urtoxazumab
Monoclonal antibody
TypeWhole antibody
Source Humanized (from mouse)
Target E. coli Shiga-like toxin II B subunit
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6414H9934N1718O2010S40
Molar mass144556.44 g·mol−1
 ☒NcheckY  (what is this?)   (verify)

Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body. [1] [2]

References

  1. ^ "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). World Health Organization.
  2. ^ López EL, Contrini MM, Glatstein E, González Ayala S, Santoro R, Allende D, et al. (January 2010). "Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli". Antimicrobial Agents and Chemotherapy. 54 (1): 239–43. doi: 10.1128/AAC.00343-09. PMC  2798559. PMID  19822704.
From Wikipedia, the free encyclopedia
Urtoxazumab
Monoclonal antibody
TypeWhole antibody
Source Humanized (from mouse)
Target E. coli Shiga-like toxin II B subunit
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6414H9934N1718O2010S40
Molar mass144556.44 g·mol−1
 ☒NcheckY  (what is this?)   (verify)

Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body. [1] [2]

References

  1. ^ "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). World Health Organization.
  2. ^ López EL, Contrini MM, Glatstein E, González Ayala S, Santoro R, Allende D, et al. (January 2010). "Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli". Antimicrobial Agents and Chemotherapy. 54 (1): 239–43. doi: 10.1128/AAC.00343-09. PMC  2798559. PMID  19822704.

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