This article may be too technical for most readers to understand. Please help improve it to make it understandable to non-experts, without removing the technical details. (October 2012) ( Learn how and when to remove this message)

This article does not cite any sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. Find sources:  "Ure2p" –  news · newspapers · books · scholar · JSTOR (December 2009) ( Learn how and when to remove this message)

Ure2p is a yeast protein that represses transcription of genes involved in nitrogen catabolism. It specifically regulates the utilization of poor nitrogen sources in the presence of preferred nutrients such as ammonia or glutamine. Ure2p is one of the few yeast proteins that are known to be prions. At low frequency the protein adopts an alternative conformation that is auto-catalytic and self-propagating. Yeast cells that carry the protein in the prion conformation are designated as [URE3]. Autocatalytic conversion of Ure2p into the inactive prion form of the protein results in a loss of repression of nitrogen catabolic genes.

References

This protein-related article is a stub. You can help Wikipedia by expanding it.

• v
• t
• e