UPMC may refer to:

• University of Pittsburgh Medical Center, an international health enterprise based in Pittsburgh, Pennsylvania, United States
• The University of the Philippines Manila Chorale, a choral music group at the University of the Philippines Manila
• Former abbreviated name of Pierre and Marie Curie University, now part of Sorbonne University, a public research university in Paris, France

See also

• UMPC, ultra-mobile personal computer, a small laptop computer

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