Ubiquitin-conjugating enzyme E2 R2 is a
protein that in humans is encoded by the UBE2R2gene.[5][6]
Protein kinase
CK2 is a ubiquitous and
pleiotropic Ser/Thr protein kinase involved in
cell growth and transformation. This gene encodes a protein similar to the E2
ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent
phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing
beta-catenin degradation.[6]
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4.
doi:
10.1016/0378-1119(94)90802-8.
PMID8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56.
doi:
10.1016/S0378-1119(97)00411-3.
PMID9373149.
Ubiquitin-conjugating enzyme E2 R2 is a
protein that in humans is encoded by the UBE2R2gene.[5][6]
Protein kinase
CK2 is a ubiquitous and
pleiotropic Ser/Thr protein kinase involved in
cell growth and transformation. This gene encodes a protein similar to the E2
ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent
phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing
beta-catenin degradation.[6]
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4.
doi:
10.1016/0378-1119(94)90802-8.
PMID8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56.
doi:
10.1016/S0378-1119(97)00411-3.
PMID9373149.