Twisted Sister(s) may refer to:

Music

• Twisted Sister, a heavy-metal band

Film and television

• Twisted Sisters, a 2006 German/UK crime thriller also known as Final Cut by director Wolfgang Büld
• Twisted Sisters, a 2016 U.S. thriller also known as Sorority Nightmare starring Sierra McCormick and Cassidy Gifford

Other

• Twisted Sisters (comic), an underground comix series by Aline Kominsky-Crumb and Diane Noomin
• "Twisted Sisters", a term used to refer to a proposed development in the Texpark site in Halifax, Nova Scotia, Canada

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