Tuffy is a nickname and a surname. It may refer to:

• Earl Abell (1892–1956), American football player
• Harold "Tuffy" Stratton (1920–1994), American football coach
• Tuffy Conn (1892–1973), American football player
• Tuffy Griffiths (1907–1968), American boxer
• Tuffy Gosewisch (born 1983), American baseball player
• Tuffy Knight (born 1936), Canadian football player
• Tuffy Leemans (1912–1979), American football player
• Tuffy Maul (1902–1974), American football player
• Tuffy Nabors (1924–1999), American football player
• Tuffy Neugen (1898–1935), Brazilian footballer
• Tuffy Rhodes (born 1968), American baseball player
• Tuffy Stewart (1883–1934), American baseball player
• Tuffy Stone (born 1962/1963), American chef and TV personality
• Tuffy Thompson (1914–2000), American football player

• Dan Tuffy ( fl. 1984–present), Australian-born musician, guitarist and vocalist
• Joanna Tuffy (born 1965), Irish politician
• Lil Tuffy (born 1972), American printmaker and designer of popular music posters

• Nibbles (Tom and Jerry), an orphan mouse also known as Tuffy
• Tuffy Smurf, a character from The Smurfs comic book series
• Tuffy, a minor character in Lady and the Tramp, a 1955 animated film
• Tuffy, in the comic included with Bazooka bubble gum - see Bazooka Joe

• Tuff (disambiguation)
• Toughie (disambiguation), including Toughy

Surname list

This page lists people with the surname Tuffy.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.