The 5th Toronto Film Critics Association Awards, honoring the best in film for 2001, were held on 20 December 2001. ^{[1] [2]}

• Best Actor:
  • Ed Harris – Pollock

Runners-Up: John Cameron Mitchell – Hedwig and the Angry Inch and Jack Nicholson – The Pledge

• Best Actress:
  • Thora Birch – Ghost World

Runners-Up: Gillian Anderson – The House of Mirth and Tilda Swinton – The Deep End

• Best Canadian Film:
  • Last Wedding

Runners-Up: Ginger Snaps and The Uncles

• Best Director:
  • David Lynch – Mulholland Dr.

Runners-Up: Jean-Pierre Jeunet – Amélie and Peter Jackson – The Lord of the Rings: The Fellowship of the Ring

• Best Film:
  • Memento

Runners-Up: Amélie and Mulholland Dr.

• Best First Feature:
  • Sexy Beast

Runners-Up: Amores Perros and In the Bedroom

• Best Screenplay:
  • Memento – Christopher Nolan

Runners-Up: Ghost World – Terry Zwigoff and Daniel Clowes and The Royal Tenenbaums – Wes Anderson and Owen Wilson

• Best Supporting Actor:
  • Ben Kingsley – Sexy Beast

Runners-Up: Steve Buscemi – Ghost World and Ian McKellen – The Lord of the Rings: The Fellowship of the Ring

• Best Supporting Actress:
  • Scarlett Johansson – Ghost World

Runners-Up: Laura Linney – The House of Mirth and Gwyneth Paltrow – The Royal Tenenbaums

• Clyde Gilmour Award:
  • James Quandt