Thomas Jefferson (1743–1826) was the president of the United States from 1801 to 1809.

Thomas Jefferson may also refer to:

• Thomas Jefferson (Caymanian politician) (1941–2006)
• Thomas Jefferson (musician) (1920–1986), American Dixieland smooth trumpeter
• Tom Jefferson (epidemiologist), British epidemiologist
• Thomas Jefferson (actor) (1856–1932), American actor
• Thomas Garland Jefferson (1847-1864), VMI cadet killed at the Battle of New Market
• Thomas Jefferson Byrd (1950–2020), American actor

• Thomas "Tommy" Jefferson, a character from Harry's Law

• Thomas Jefferson: Author of America, a short biography by Christopher Hitchens
• Thomas Jefferson (film), a 1997 film by Ken Burns

• Thomas Jefferson (Bitter), a 1915 sculpture by Karl Bitter in Cleveland, Ohio
• Statue of Thomas Jefferson (Columbia University), a 1914 sculpture by William Ordway Partridge in Manhattan, New York
• Thomas Jefferson (University of Virginia), a statue in front of the Rotunda

• USS Thomas Jefferson, a U.S. Navy shipname
  • USS Thomas Jefferson (APA-30), an attack transport in service from 1941 to 1949
  • USS Thomas Jefferson (SSBN-618), an Ethan Allen-class ballistic missile submarine commissioned in 1963
• NOAAS Thomas Jefferson (S 222), a United States National Oceanic and Atmospheric Administration hydrographic survey ship

• Thomas Jefferson Junior High School (disambiguation)
• Thomas Jefferson Middle School (disambiguation)
• Thomas Jefferson University, Philadelphia, Pennsylvania
• Thomas Jefferson School of Law, San Diego, California

• Thomas Jefferson Association Building, Brooklyn, New York, demolished in 1960
• Thomas Jefferson Hotel, a former hotel in Birmingham, Alabama
• Thomas Jefferson Library, the main library for the University of Missouri–St. Louis
• Thomas Jefferson National Accelerator Facility, a national laboratory in Newport News, Virginia

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• Jefferson (disambiguation)
• Thomas (disambiguation)

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