Names | |
---|---|
IUPAC name
3-(Dimethylcarbamoylimino)-1,1-dimethylurea
| |
Other names
Diamide; Tetramethyldiazenedicarboxamide; N,N,N′,N′-Tetramethylazoformamide 1,1'-Azobis(N,N-dimethylformamide); N,N,N′,N′-Tetramethylazobisformamide; Azodicarboxylic acid bis(dimethylamide); 1,1'-Azobis(N,N-dimethylformamide)
| |
Identifiers | |
3D model (
JSmol)
|
|
Abbreviations | TMAD |
ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.030.852 |
EC Number |
|
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C6H12N4O2 | |
Molar mass | 172.188 g·mol−1 |
Appearance | Yellow crystalline solid |
Melting point | 113 to 115 °C (235 to 239 °F; 386 to 388 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Tetramethylazodicarboxamide (also known as TMAD and diamide) is a reagent used in biochemistry for oxidation of thiols in proteins to disulfides. [2] It has also been used as a reagent in the Mitsunobu reaction in place of diethyl azodicarboxylate. [1]
Names | |
---|---|
IUPAC name
3-(Dimethylcarbamoylimino)-1,1-dimethylurea
| |
Other names
Diamide; Tetramethyldiazenedicarboxamide; N,N,N′,N′-Tetramethylazoformamide 1,1'-Azobis(N,N-dimethylformamide); N,N,N′,N′-Tetramethylazobisformamide; Azodicarboxylic acid bis(dimethylamide); 1,1'-Azobis(N,N-dimethylformamide)
| |
Identifiers | |
3D model (
JSmol)
|
|
Abbreviations | TMAD |
ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.030.852 |
EC Number |
|
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C6H12N4O2 | |
Molar mass | 172.188 g·mol−1 |
Appearance | Yellow crystalline solid |
Melting point | 113 to 115 °C (235 to 239 °F; 386 to 388 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Tetramethylazodicarboxamide (also known as TMAD and diamide) is a reagent used in biochemistry for oxidation of thiols in proteins to disulfides. [2] It has also been used as a reagent in the Mitsunobu reaction in place of diethyl azodicarboxylate. [1]