Crohn's disease | Ulcerative colitis | |
---|---|---|
Terminal ileum involvement | Commonly | Seldom |
Colon involvement | Usually | Always |
Rectum involvement | Seldom | Usually (95%) [1] |
Involvement around the anus |
Common [2] | Seldom |
Bile duct involvement | No increase in rate of primary sclerosing cholangitis | Higher rate [3] |
Distribution of disease | Patchy areas of inflammation (skip lesions) | Continuous area of inflammation [1] |
Endoscopy | Deep geographic and serpiginous (snake-like) ulcers | Continuous ulcer |
Depth of inflammation | May be transmural, deep into tissues [2] [4] | Shallow, mucosal |
Stenosis | Common | Seldom |
Granulomas on biopsy | May have non- necrotizing non-peri- intestinal crypt granulomas [2] [5] [6] | Non-peri- intestinal crypt granulomas not seen [7] |
The tables in this series compare Crohn's disease and ulcerative colitis, the main types of inflammatory bowel disease, and are used in both articles.
{{
cite journal}}
: CS1 maint: DOI inactive as of January 2024 (
link)
Crohn's disease | Ulcerative colitis | |
---|---|---|
Terminal ileum involvement | Commonly | Seldom |
Colon involvement | Usually | Always |
Rectum involvement | Seldom | Usually (95%) [1] |
Involvement around the anus |
Common [2] | Seldom |
Bile duct involvement | No increase in rate of primary sclerosing cholangitis | Higher rate [3] |
Distribution of disease | Patchy areas of inflammation (skip lesions) | Continuous area of inflammation [1] |
Endoscopy | Deep geographic and serpiginous (snake-like) ulcers | Continuous ulcer |
Depth of inflammation | May be transmural, deep into tissues [2] [4] | Shallow, mucosal |
Stenosis | Common | Seldom |
Granulomas on biopsy | May have non- necrotizing non-peri- intestinal crypt granulomas [2] [5] [6] | Non-peri- intestinal crypt granulomas not seen [7] |
The tables in this series compare Crohn's disease and ulcerative colitis, the main types of inflammatory bowel disease, and are used in both articles.
{{
cite journal}}
: CS1 maint: DOI inactive as of January 2024 (
link)