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Eicosanoids
Precursor
Arachidonic acid
Prostanoids
Prostaglandins
(PG)
Precursor
H
2
Active
D/J
D
2
E
/F
E
2
(Dinoprostone)
E
1
(Alprostadil)
F
2α
(Dinoprost)
:
I
I
2
(Prostacyclin/Epoprostenol)
:
Thromboxanes
(TX)
A
2
B
2
Leukotrienes
(LT)
Precursor
Arachidonic acid 5-hydroperoxide
Initial
A
4
B
4
SRS-A
C
4
D
4
E
4
Eoxins
(EX)
Precursor
Arachidonic acid 15-hydroperoxide
Eoxins
A
4
C
4
D
4
E
4
Nonclassic
Lipoxins
(LX) (
A
4
,
B
4
)
Virodhamine
By function
bronchoconstriction
PGD
2
TXA
2
LTC
4
LTD
4
LTE
4
vasoconstriction
PGF
2α
TXA
2
TXB
2
vasodilation
PGE
2
PGI
2
LTC
4
LTD
4
LTE
4
platelets
: induce
TXA
2
inhibit
PGD
2
PGI
2
leukocytes
: induce
TXA
2
LTB
4
inhibit
PGD
2
PGE
2
fever
stimulation:
PGE
2
labor
stimulation:
PGE
2
(Dinoprostone)
PGF
2α
(Dinoprost)
Category
:
Lipid metabolic pathway navigational boxes
From Wikipedia, the free encyclopedia
v
t
e
Eicosanoids
Precursor
Arachidonic acid
Prostanoids
Prostaglandins
(PG)
Precursor
H
2
Active
D/J
D
2
E
/F
E
2
(Dinoprostone)
E
1
(Alprostadil)
F
2α
(Dinoprost)
:
I
I
2
(Prostacyclin/Epoprostenol)
:
Thromboxanes
(TX)
A
2
B
2
Leukotrienes
(LT)
Precursor
Arachidonic acid 5-hydroperoxide
Initial
A
4
B
4
SRS-A
C
4
D
4
E
4
Eoxins
(EX)
Precursor
Arachidonic acid 15-hydroperoxide
Eoxins
A
4
C
4
D
4
E
4
Nonclassic
Lipoxins
(LX) (
A
4
,
B
4
)
Virodhamine
By function
bronchoconstriction
PGD
2
TXA
2
LTC
4
LTD
4
LTE
4
vasoconstriction
PGF
2α
TXA
2
TXB
2
vasodilation
PGE
2
PGI
2
LTC
4
LTD
4
LTE
4
platelets
: induce
TXA
2
inhibit
PGD
2
PGI
2
leukocytes
: induce
TXA
2
LTB
4
inhibit
PGD
2
PGE
2
fever
stimulation:
PGE
2
labor
stimulation:
PGE
2
(Dinoprostone)
PGF
2α
(Dinoprost)
Category
:
Lipid metabolic pathway navigational boxes
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