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What is a "fold-change"? The usage here seems different from that given in fold change, which seems to indicate a value that is always greater than one, while here the example shows that values can be less than one. Perhaps something more direct needs to be said here anyway. Melcombe ( talk) 12:19, 4 January 2010 (UTC)
I just made an edit. A previous editor said the p-values are normally distributed, but this is unclear. For ex, iinm, with random data, p-values assumea uniform distribution across the (0,1) interval. I believe the statement was meant to say something about the distribution of the p-values against the log-fold changes, but this wasn't explained legibly, and I am not enough of a statistician to explain it better. Parabolas do sometimes appear in volcano plots (seen here http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=Volcano_plots.html ) , but someone else will have to explain why that is. Flies 1 ( talk) 18:34, 15 January 2021 (UTC)
This source may be useful to describe such plots. Jo-Jo Eumerus ( talk) 14:45, 17 November 2023 (UTC)
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||||||||||
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What is a "fold-change"? The usage here seems different from that given in fold change, which seems to indicate a value that is always greater than one, while here the example shows that values can be less than one. Perhaps something more direct needs to be said here anyway. Melcombe ( talk) 12:19, 4 January 2010 (UTC)
I just made an edit. A previous editor said the p-values are normally distributed, but this is unclear. For ex, iinm, with random data, p-values assumea uniform distribution across the (0,1) interval. I believe the statement was meant to say something about the distribution of the p-values against the log-fold changes, but this wasn't explained legibly, and I am not enough of a statistician to explain it better. Parabolas do sometimes appear in volcano plots (seen here http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=Volcano_plots.html ) , but someone else will have to explain why that is. Flies 1 ( talk) 18:34, 15 January 2021 (UTC)
This source may be useful to describe such plots. Jo-Jo Eumerus ( talk) 14:45, 17 November 2023 (UTC)