From Wikipedia, the free encyclopedia

Pregabalin contradiction?

"Antidepressant medications, such as amitriptyline have shown good efficacy in treating trigeminal neuralgia, especially if combined with an anti-convulsant drug such as pregabalin.[27]"

This is in contradiction with the article on Pregabalin:

"Pregabalin is not recommended for certain other types of neuropathic pain such as trigeminal neuralgia[31] and its use in cancer-associated neuropathic pain is controversial.[31]" ( /info/en/?search=Pregabalin)

What gives?

Sobeita ( talk) 20:03, 23 July 2018 (UTC) reply

By now the statement is no longer there so I can't check the source either, but pregabalin is commonly used as a second-line TN treatment when things like carbamazepine fail, and this is mentioned in a number of papers, so should someone want to add the statement again, I am confident there is a lot to (not) back it. LjL ( talk) 00:50, 29 April 2023 (UTC) reply

Lancet neurology

doi:10.1016/S1474-4422(20)30233-7 JFW |  T@lk 15:01, 19 August 2020 (UTC) reply

NEJM

doi:10.1056/NEJMra1914484 JFW |  T@lk 22:18, 19 August 2020 (UTC) reply

Thanks for this, interesting for both my job and the article. - After briefly reading this article I did not substantial improvements that need to be made. Will work on it soon. PainProf ( talk) 15:25, 20 August 2020 (UTC) reply

Epidemiology cited wrongly

Hi, The epidemiology of trigeminal neuralgia is wrongly cited from the source. Instead of 1 in 8000 per year it should be 12 in 100000 a year.

From Wikipedia, the free encyclopedia

Pregabalin contradiction?

"Antidepressant medications, such as amitriptyline have shown good efficacy in treating trigeminal neuralgia, especially if combined with an anti-convulsant drug such as pregabalin.[27]"

This is in contradiction with the article on Pregabalin:

"Pregabalin is not recommended for certain other types of neuropathic pain such as trigeminal neuralgia[31] and its use in cancer-associated neuropathic pain is controversial.[31]" ( /info/en/?search=Pregabalin)

What gives?

Sobeita ( talk) 20:03, 23 July 2018 (UTC) reply

By now the statement is no longer there so I can't check the source either, but pregabalin is commonly used as a second-line TN treatment when things like carbamazepine fail, and this is mentioned in a number of papers, so should someone want to add the statement again, I am confident there is a lot to (not) back it. LjL ( talk) 00:50, 29 April 2023 (UTC) reply

Lancet neurology

doi:10.1016/S1474-4422(20)30233-7 JFW |  T@lk 15:01, 19 August 2020 (UTC) reply

NEJM

doi:10.1056/NEJMra1914484 JFW |  T@lk 22:18, 19 August 2020 (UTC) reply

Thanks for this, interesting for both my job and the article. - After briefly reading this article I did not substantial improvements that need to be made. Will work on it soon. PainProf ( talk) 15:25, 20 August 2020 (UTC) reply

Epidemiology cited wrongly

Hi, The epidemiology of trigeminal neuralgia is wrongly cited from the source. Instead of 1 in 8000 per year it should be 12 in 100000 a year.


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