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A few of problems.

1) It is no longer widely believed that Sec61 plays a role in retro-translocation.

2) As far as I know the translocon ONLY refers to the homologous Sec61 and SecYEG channels.

3) Not all translocated proteins have signal sequences, for example type II membrane-bound proteins.

4) Translocons also have lateral gates that allow transmembrane domains to anter the lipid bilayer.

Microtubules ( talk) 18:27, 23 August 2012 (UTC) reply