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Hi, As part of our Molecular Biology class project we are planning to update this article by adding some additional information. We plant to post the following sections soon and hope to add some images as well.
Mechanism
Discovery
Biosynthesis
Examples of plants in which this is found
Feedback or suggestions will always be very welcome. Katesee ( talk) 21:17, 15 November 2012 (UTC)
Hi Group 83D, while this seems like a difficult topic to discuss. However, my suggestions are as follows: Under the mechanism section, it will be helpful to link si-RNA to other wiki sites to allow the reader gain a better understanding of si-RNA. Under the biosynthesis section, it will be helpful to include a figure that describes the details of the biosynthesis pathway. It may also be helpful to place your discovery section before the mechanism section because the details seem like a history section. It will also be helpful to add a little more detail to the possible uses of a trans-acting RNA in today's world of medicine. Other helpful suggestions is to include more description of the importance of trans-acting pathway. Seguncha ( talk) 14:57, 28 November 2012 (UTC)
I think you guys have done a wonderful job in organizing the article and making it easy to read. The only suggestion I have is adding some figures, as Seguncha has stated. Skhan58 ( talk) 18:09, 2 December 2012 (UTC)
The article looks really good and very "wikipedia like"! Here are more detailed suggestions (sorry my last post was not in depth).
Otherwise, great job!
Skhan58 ( talk) 06:19, 6 December 2012 (UTC)
Hi, guys. Here's a final-week mini-review of your page. It is just a few random notes, that I jotted down while skimming the page, and is not intended as a comprehensive review.
Klortho ( talk) 03:31, 10 December 2012 (UTC)
I don't agree with this statement in the introductory paragraph: 'ta-siRNAs differ from other siRNAs in that they bind with less sequence specificity to their targets.[2]' Complementarity of several tasiRNAs to their targets is quite good, and there hasn't been enough mechanistic analysis to say much beyond that. The next sentence ('They function more like microRNAs because they do not require full sequence complementarity in order to direct cleavage of the target RNA.[4]') sounds like it is comparing plant tasiRNA to animal miRNA, which often only match targets in their 'seed' region.
The 'Presence in Plants' section could be improved to emphasize that the TAS3 gene family is conserved in almost all land plants, while other families studied so far are lineage-specific. I just made a quick edit about Arabidopsis-specific gene family numbering.
It might be worth citing Rui et al., and/or Xia et al., and/or Cho et al. and/or Banks et al.
![]() | This article has not yet been rated on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||
|
Hi, As part of our Molecular Biology class project we are planning to update this article by adding some additional information. We plant to post the following sections soon and hope to add some images as well.
Mechanism
Discovery
Biosynthesis
Examples of plants in which this is found
Feedback or suggestions will always be very welcome. Katesee ( talk) 21:17, 15 November 2012 (UTC)
Hi Group 83D, while this seems like a difficult topic to discuss. However, my suggestions are as follows: Under the mechanism section, it will be helpful to link si-RNA to other wiki sites to allow the reader gain a better understanding of si-RNA. Under the biosynthesis section, it will be helpful to include a figure that describes the details of the biosynthesis pathway. It may also be helpful to place your discovery section before the mechanism section because the details seem like a history section. It will also be helpful to add a little more detail to the possible uses of a trans-acting RNA in today's world of medicine. Other helpful suggestions is to include more description of the importance of trans-acting pathway. Seguncha ( talk) 14:57, 28 November 2012 (UTC)
I think you guys have done a wonderful job in organizing the article and making it easy to read. The only suggestion I have is adding some figures, as Seguncha has stated. Skhan58 ( talk) 18:09, 2 December 2012 (UTC)
The article looks really good and very "wikipedia like"! Here are more detailed suggestions (sorry my last post was not in depth).
Otherwise, great job!
Skhan58 ( talk) 06:19, 6 December 2012 (UTC)
Hi, guys. Here's a final-week mini-review of your page. It is just a few random notes, that I jotted down while skimming the page, and is not intended as a comprehensive review.
Klortho ( talk) 03:31, 10 December 2012 (UTC)
I don't agree with this statement in the introductory paragraph: 'ta-siRNAs differ from other siRNAs in that they bind with less sequence specificity to their targets.[2]' Complementarity of several tasiRNAs to their targets is quite good, and there hasn't been enough mechanistic analysis to say much beyond that. The next sentence ('They function more like microRNAs because they do not require full sequence complementarity in order to direct cleavage of the target RNA.[4]') sounds like it is comparing plant tasiRNA to animal miRNA, which often only match targets in their 'seed' region.
The 'Presence in Plants' section could be improved to emphasize that the TAS3 gene family is conserved in almost all land plants, while other families studied so far are lineage-specific. I just made a quick edit about Arabidopsis-specific gene family numbering.
It might be worth citing Rui et al., and/or Xia et al., and/or Cho et al. and/or Banks et al.