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The statement "In some cases the structures of the molecules assigned by spectroscopic methods have been shown to be wrong, when synthesised." is unclear. Does this mean that the synthetic compound provided the correct spectrograph that could not be obtained from the original (because of impurities, irregular crystal habits, etc.)? Or does this mean that the synthetic compound is a new isomer that can only be distinguished from the original by a spectrograph? Collin237 —Preceding unsigned comment added by 166.217.232.85 ( talk) 11:44, 29 March 2011 (UTC)
Le Prof 71.239.82.39 ( talk) 02:41, 30 April 2014 (UTC)
The article claims that camphor was the first commercial total synthesis, but the first reference discusses the synthesis of alizarin in 1869 as having spurred the German dye industry. The alizarin page itself discusses the synthesis and notes that the market for the compound from its traditional source collapsed overnight upon the report of the synthesis. —Preceding unsigned comment added by 136.152.155.72 ( talk) 23:38, 19 April 2011 (UTC)
This is not about this article, but about articles within Category:Total synthesis. See Talk:Morphine#Merge_morphine_total_synthesis for a discussion. Blue Rasberry (talk) 16:56, 22 January 2014 (UTC)
A significant proportion of all drugs on market have links to natural products chemistry, and total synthesis is central to their development, understandings of their mechanism of action, etc. As well, total synthesis is considered the single greatest motivation and proving ground of new, general synthetic methodology, and provides the most highly regarded of training venues for synthetic organic chemists for academia and industry. This article does not begin to relate the central importance of this subject to all of modern organic chemistry, in the past century or in the beginnings of this one. Le Prof 71.239.82.39 ( talk) 02:49, 30 April 2014 (UTC)
...to this article, I have addressed what serious deficiencies I can, quickly, and tagged the rest to call further attention to the article. As long as this article is so poor, there will be broad misunderstanding by others here at WP, about the distinctiveness of TS work, and its fundamental importance to org synth and medichem. Please, others, bring what you can to bear on this article. See edit summaries for the specific changes made. Note, I have great respect for KC's group and corpus, but his work should not form the sole basis for this article (obviously), and passing mentions of Corey syntheses, inserted unreferenced, cannot be tolerated as a practice. Le Prof Leprof 7272 ( talk) 06:01, 5 June 2014 (UTC)
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I made an invisible comment about this. The examples section should be expanded a lot and be made into a list. There are dozens of very good total synthesis examples that can be listed to highlight the bredth and importance of total synthesis, some of which should be able to be linked to wiki pages. Though, it is not necessary to linked them to wiki pages, it could also be used as an opertunity to make red links to pages that should be created.
While I could do this, I admit that I don't particularly want to lol (hence me sharing it as an idea on the talk page). Maybe I will in the future.
As a side note, the history section should probably be overhauled when the example section is expanded.
This
level-5 vital article is rated Start-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||
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The statement "In some cases the structures of the molecules assigned by spectroscopic methods have been shown to be wrong, when synthesised." is unclear. Does this mean that the synthetic compound provided the correct spectrograph that could not be obtained from the original (because of impurities, irregular crystal habits, etc.)? Or does this mean that the synthetic compound is a new isomer that can only be distinguished from the original by a spectrograph? Collin237 —Preceding unsigned comment added by 166.217.232.85 ( talk) 11:44, 29 March 2011 (UTC)
Le Prof 71.239.82.39 ( talk) 02:41, 30 April 2014 (UTC)
The article claims that camphor was the first commercial total synthesis, but the first reference discusses the synthesis of alizarin in 1869 as having spurred the German dye industry. The alizarin page itself discusses the synthesis and notes that the market for the compound from its traditional source collapsed overnight upon the report of the synthesis. —Preceding unsigned comment added by 136.152.155.72 ( talk) 23:38, 19 April 2011 (UTC)
This is not about this article, but about articles within Category:Total synthesis. See Talk:Morphine#Merge_morphine_total_synthesis for a discussion. Blue Rasberry (talk) 16:56, 22 January 2014 (UTC)
A significant proportion of all drugs on market have links to natural products chemistry, and total synthesis is central to their development, understandings of their mechanism of action, etc. As well, total synthesis is considered the single greatest motivation and proving ground of new, general synthetic methodology, and provides the most highly regarded of training venues for synthetic organic chemists for academia and industry. This article does not begin to relate the central importance of this subject to all of modern organic chemistry, in the past century or in the beginnings of this one. Le Prof 71.239.82.39 ( talk) 02:49, 30 April 2014 (UTC)
...to this article, I have addressed what serious deficiencies I can, quickly, and tagged the rest to call further attention to the article. As long as this article is so poor, there will be broad misunderstanding by others here at WP, about the distinctiveness of TS work, and its fundamental importance to org synth and medichem. Please, others, bring what you can to bear on this article. See edit summaries for the specific changes made. Note, I have great respect for KC's group and corpus, but his work should not form the sole basis for this article (obviously), and passing mentions of Corey syntheses, inserted unreferenced, cannot be tolerated as a practice. Le Prof Leprof 7272 ( talk) 06:01, 5 June 2014 (UTC)
Hello fellow Wikipedians,
I have just modified one external link on Total synthesis. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
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(last update: 5 June 2024).
Cheers.— InternetArchiveBot ( Report bug) 18:56, 8 September 2017 (UTC)
I made an invisible comment about this. The examples section should be expanded a lot and be made into a list. There are dozens of very good total synthesis examples that can be listed to highlight the bredth and importance of total synthesis, some of which should be able to be linked to wiki pages. Though, it is not necessary to linked them to wiki pages, it could also be used as an opertunity to make red links to pages that should be created.
While I could do this, I admit that I don't particularly want to lol (hence me sharing it as an idea on the talk page). Maybe I will in the future.
As a side note, the history section should probably be overhauled when the example section is expanded.