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This section was out of date. On top of that, the references it cited had been updated since the article was last written, so that the article no longer reflected the material in the references, especially in regards to the WHO website. Updated this. Also, removed a bunch of material which inaccurately quoted the WHO website. Would like to add the position of the WHO back, but no time right now - felt it was better to have no information than complete misinformation. corvus.ag ( talk) 04:50, 26 October 2009 (UTC)
Ackowledge that there is a controversy on the health effects of squalene, but keep the main emphasis on the chemical and biochemical aspects. -- tom ( talk) 22:49, 2 September 2009 (UTC)
It mentions squalene being implicated in Gulf War syndrome but there are no citations to support this. —Preceding unsigned comment added by Contributions/85.28.112.249 ([[User talk:|talk]]) 12:04, 24 August 2009 (UTC)
The claims about Gulf War syndrome have been debunked on several levels, and I have added a WHO citation to support this. Squaline was not administered to Gulf War Veterans, nor does the administration of Squaline significantly increase or decrease the level of Squaline anti-bodies in humans. Squaline anti-bodies are found in nearly 100% of humans as it is produced by the body, and its concentration increases with age. These three separate facts are heavily supported by research and each independently contradicts and discredit the one report suggesting a link.
The claim that nearly all Gulf War Syndrome patients have squaline antibodies is extremely misleading. Numerous studies have shown that squaline antibodies are naturally ocurring in humans, and other studies have exposed the original study as deeply flawed and biased. —Preceding unsigned comment added by Contributions/160.33.43.65 ([[User talk:|talk]]) 22:04, 26 August 2009 (UTC)
My goodness, he can not even spell squalene and then he wants to post about it.
I went ahead and erased and rewrote the Controversy section because it was really misleading (quoting part of a study to support your claims when the study actually specifically debunks said claims) and we're hearing more and more about this Squalene stuff being a hidden danger that will kill us all, so I figured we should handle the "gulf war syndrome" connection.-- Brad R. ( talk) 19:36, 28 September 2009 (UTC)
ALLERGIC TO SQUALENE!! Are they out their minds?? Why would the human body produce antibodies against squalene when the body naturally produces the substance? The next thing they will be telling us the human body is allergic to water!! The DOD paid a researcher to make Squalene antibodies, a complete waste of taxpayer money. The researcher could not. What he did do however, was to force the mice to make the antibodies using other substances in conjunction with the squalene and then had the nerve to suggest he had made antibodies to squalene. Alice in Wonderland. For DOD study results See page 7 of http://www.fda.gov/ohrms/dockets/dockets/80n0208/80n-0208-c000037-15-01-vol151.pdf 65.255.192.26 ( talk) 18:24, 23 February 2016 (UTC) Dr Raymond A. Schep.
The stereochemistry of one of the alkenes in the 3-D structure of squalene is incorrect. —Preceding unsigned comment added by Phil Strucely ( talk • contribs) 00:06, 16 December 2007 (UTC)
here is a reference for the rat model with mycobacteria, i dont know how to insert into text , if someone would like to help? http://www.ncbi.nlm.nih.gov/pubmed/18438855?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=5 Heinzmorrison ( talk) 07:16, 11 November 2009 (UTC)
When I went to this link, I got a warning message from Google that it was a "Reported Attack Site!"
I have deleted the url link (but not the article citation) from the article page and moved it here. I don't suggest anybody try it unless you're prepared to handle malware.
Here's the link: http://www.avip2001.net/OfficialDocuments_files/Asa_squalene.pdf Antibodies to Squalene in Recipients of Anthrax Vaccine Experimental and Molecular Pathology 73, 19–27, 2002
Here's some of the message:
What happened when Google visited this site?
Of the 7 pages we tested on the site over the past 90 days, 4 page(s) resulted in malicious software being downloaded and installed without user consent. The last time Google visited this site was on 2009-06-29, and the last time suspicious content was found on this site was on 2009-06-29.
Malicious software includes 20 scripting exploit(s).
Malicious software is hosted on 1 domain(s), including gumblar.cn/.
This site was hosted on 1 network(s) including AS29873 (BIZLAND).
-- Nbauman ( talk) 18:06, 10 July 2009 (UTC)
One sentence in the article reads as follows: "A review of this study by the AFEB found severe shortcomings in the methodology used and found them to contradict the actual claims made[4]." However, we are not told what the abbreviation AFEB means. When using abbreviations in writting, always spell out the full name or phrase the first time the abreviation appears, with the abbreviation following in parenthasis. Example: "American Medical Association (AMA)." Thereafter, you may use the abbreviation alone. —Preceding unsigned comment added by Ex89158 ( talk • contribs) 15:47, 27 August 2009 (UTC)
I was very disappointed to be directed to "terpene" when I selected the link "triterpene". Unfree ( talk) 18:38, 8 September 2009 (UTC)
I think this part of the page needs extending, rather than putting external links in support. I came to this page because of things I had seen about the H1N1 vaccine, PURELY to find out what the controversies were. I'm sure the same is true for a lot of people currently researching this compound
3/5/21 And why is it only added to the flu shot for people over 65? I believe this is also the practice in Europe. Why not everyone? It was in the H1N1 vaccine (experiment?). It must be a powerful adjuvant. And it was later found that if you got the H1N1 vaccine you were more prone to getting the flu. No ref, sorry. Rkcannon ( talk) 05:54, 21 September 2010 (UTC) — Preceding unsigned comment added by 98.214.160.215 ( talk)
People with time should read the following section:
http://en.wikipedia.org/wiki/Gulf_War_syndrome#Anthrax vaccine and update the controversy section of this article. —Preceding
unsigned comment added by
Contributions/173.177.13.157 ([[User talk:|talk]])
03:48, 28 October 2009 (UTC)
This reads like an ad copy and contradicts the discussion about squalene in vaccines and the fact that it naturally occurs in the bloodstream as a cholesterol precursor. In fact, the source article "articles.mercola.com/sites/articles/archive/2009/08/04/Squalene-The-Swine-Flu-Vaccines-Dirty-Little-Secret-Exposed.aspx unreliable fringe source?" is largely bunk, linking to articles about disproven links to Gulf War Syndrome and Autism by vaccine. In addition, the following source ( http://www.amazon.com/Science-Behind-Squalene-Human-Antioxidant/dp/1890412953) seems much less appropriate than PubMed links.
(opinion) The whole section reads like a supplement proponent trying to validate their own use of squalene while still clinging to the belief that 'squalene == bad' and I think the whole section needs to be purged or rewritten. (/opinion) Contributions/64.201.177.59 ([[User talk:|talk]]) 15:19, 17 November 2009 (UTC)
Apparently, this compound is found in human vaginal fluids in appreciably higher concentrations than what humans of both sexes use in Vitamin D and cholesterol synthesis. At least, it sounds that way here [5]. The Mysterious El Willstro ( talk) 06:20, 27 June 2010 (UTC)
Swedish and finnish studies have found a signifikant increase of narcolepsia in children who where vaccinated with pandemrix durind the swineflu. They claim that the squalene is the cause. —Preceding unsigned comment added by 81.226.64.67 ( talk) 06:01, 30 March 2011 (UTC)
The value of the melting point is reported as either -75 °C or -5 °C in many sources. The -75 value seems dubiously low in comparison to other long chain hydrocarbons, but it is reported in normally reliable secondary sources including the Merck Index. The precise value of -4.8 to -5.2 °C reported in the 1974 Angewandte Chemie paper seems the most reliable in my opinion, so I have put that one in the chembox. -- Ed ( Edgar181) 20:09, 3 April 2013 (UTC)
The structures of farnesyl pyrophosphate are missing an O in the pyrophosphate (between the two phosphorus atoms). 69.72.92.71 ( talk) 06:32, 22 December 2015 (UTC)
The comment(s) below were originally left at Talk:Squalene/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.
It mentions squalene being related to Gulf War syndrome but I cannot find any scientific literature to back this up, only sites that have poor credibility. "obtained for commercial purposes primarily from shark liver oil (hence its name)" Maybe I'm missing something, but to me it's not clear how the name "squalene" is related to squalene's production from shark liver oil. Etymologically, I mean. |
Substituted at 06:46, 30 April 2016 (UTC)
Mercola is claiming that up to a half a million sharks will be killed to make enough squalene to create “satisfy a global supply of squalene-containing vaccines”. He quotes from a New Zealand Herald article which quotes the “California-based group Shark Allies”.
If this is true, I will add a few sentences about how the manufacture of squalene has an impact on shark populations.
I don’t know what percent of the worldwide shock population is impacted?
Is there an alternative to extracting squalene from dead sharks?
https://principia-scientific.com/a-half-million-sharks-to-be-killed-for-covid-19-vaccine/ Phersh ( talk) 02:22, 10 October 2020 (UTC)
![]() | This ![]() It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||
|
This section was out of date. On top of that, the references it cited had been updated since the article was last written, so that the article no longer reflected the material in the references, especially in regards to the WHO website. Updated this. Also, removed a bunch of material which inaccurately quoted the WHO website. Would like to add the position of the WHO back, but no time right now - felt it was better to have no information than complete misinformation. corvus.ag ( talk) 04:50, 26 October 2009 (UTC)
Ackowledge that there is a controversy on the health effects of squalene, but keep the main emphasis on the chemical and biochemical aspects. -- tom ( talk) 22:49, 2 September 2009 (UTC)
It mentions squalene being implicated in Gulf War syndrome but there are no citations to support this. —Preceding unsigned comment added by Contributions/85.28.112.249 ([[User talk:|talk]]) 12:04, 24 August 2009 (UTC)
The claims about Gulf War syndrome have been debunked on several levels, and I have added a WHO citation to support this. Squaline was not administered to Gulf War Veterans, nor does the administration of Squaline significantly increase or decrease the level of Squaline anti-bodies in humans. Squaline anti-bodies are found in nearly 100% of humans as it is produced by the body, and its concentration increases with age. These three separate facts are heavily supported by research and each independently contradicts and discredit the one report suggesting a link.
The claim that nearly all Gulf War Syndrome patients have squaline antibodies is extremely misleading. Numerous studies have shown that squaline antibodies are naturally ocurring in humans, and other studies have exposed the original study as deeply flawed and biased. —Preceding unsigned comment added by Contributions/160.33.43.65 ([[User talk:|talk]]) 22:04, 26 August 2009 (UTC)
My goodness, he can not even spell squalene and then he wants to post about it.
I went ahead and erased and rewrote the Controversy section because it was really misleading (quoting part of a study to support your claims when the study actually specifically debunks said claims) and we're hearing more and more about this Squalene stuff being a hidden danger that will kill us all, so I figured we should handle the "gulf war syndrome" connection.-- Brad R. ( talk) 19:36, 28 September 2009 (UTC)
ALLERGIC TO SQUALENE!! Are they out their minds?? Why would the human body produce antibodies against squalene when the body naturally produces the substance? The next thing they will be telling us the human body is allergic to water!! The DOD paid a researcher to make Squalene antibodies, a complete waste of taxpayer money. The researcher could not. What he did do however, was to force the mice to make the antibodies using other substances in conjunction with the squalene and then had the nerve to suggest he had made antibodies to squalene. Alice in Wonderland. For DOD study results See page 7 of http://www.fda.gov/ohrms/dockets/dockets/80n0208/80n-0208-c000037-15-01-vol151.pdf 65.255.192.26 ( talk) 18:24, 23 February 2016 (UTC) Dr Raymond A. Schep.
The stereochemistry of one of the alkenes in the 3-D structure of squalene is incorrect. —Preceding unsigned comment added by Phil Strucely ( talk • contribs) 00:06, 16 December 2007 (UTC)
here is a reference for the rat model with mycobacteria, i dont know how to insert into text , if someone would like to help? http://www.ncbi.nlm.nih.gov/pubmed/18438855?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=5 Heinzmorrison ( talk) 07:16, 11 November 2009 (UTC)
When I went to this link, I got a warning message from Google that it was a "Reported Attack Site!"
I have deleted the url link (but not the article citation) from the article page and moved it here. I don't suggest anybody try it unless you're prepared to handle malware.
Here's the link: http://www.avip2001.net/OfficialDocuments_files/Asa_squalene.pdf Antibodies to Squalene in Recipients of Anthrax Vaccine Experimental and Molecular Pathology 73, 19–27, 2002
Here's some of the message:
What happened when Google visited this site?
Of the 7 pages we tested on the site over the past 90 days, 4 page(s) resulted in malicious software being downloaded and installed without user consent. The last time Google visited this site was on 2009-06-29, and the last time suspicious content was found on this site was on 2009-06-29.
Malicious software includes 20 scripting exploit(s).
Malicious software is hosted on 1 domain(s), including gumblar.cn/.
This site was hosted on 1 network(s) including AS29873 (BIZLAND).
-- Nbauman ( talk) 18:06, 10 July 2009 (UTC)
One sentence in the article reads as follows: "A review of this study by the AFEB found severe shortcomings in the methodology used and found them to contradict the actual claims made[4]." However, we are not told what the abbreviation AFEB means. When using abbreviations in writting, always spell out the full name or phrase the first time the abreviation appears, with the abbreviation following in parenthasis. Example: "American Medical Association (AMA)." Thereafter, you may use the abbreviation alone. —Preceding unsigned comment added by Ex89158 ( talk • contribs) 15:47, 27 August 2009 (UTC)
I was very disappointed to be directed to "terpene" when I selected the link "triterpene". Unfree ( talk) 18:38, 8 September 2009 (UTC)
I think this part of the page needs extending, rather than putting external links in support. I came to this page because of things I had seen about the H1N1 vaccine, PURELY to find out what the controversies were. I'm sure the same is true for a lot of people currently researching this compound
3/5/21 And why is it only added to the flu shot for people over 65? I believe this is also the practice in Europe. Why not everyone? It was in the H1N1 vaccine (experiment?). It must be a powerful adjuvant. And it was later found that if you got the H1N1 vaccine you were more prone to getting the flu. No ref, sorry. Rkcannon ( talk) 05:54, 21 September 2010 (UTC) — Preceding unsigned comment added by 98.214.160.215 ( talk)
People with time should read the following section:
http://en.wikipedia.org/wiki/Gulf_War_syndrome#Anthrax vaccine and update the controversy section of this article. —Preceding
unsigned comment added by
Contributions/173.177.13.157 ([[User talk:|talk]])
03:48, 28 October 2009 (UTC)
This reads like an ad copy and contradicts the discussion about squalene in vaccines and the fact that it naturally occurs in the bloodstream as a cholesterol precursor. In fact, the source article "articles.mercola.com/sites/articles/archive/2009/08/04/Squalene-The-Swine-Flu-Vaccines-Dirty-Little-Secret-Exposed.aspx unreliable fringe source?" is largely bunk, linking to articles about disproven links to Gulf War Syndrome and Autism by vaccine. In addition, the following source ( http://www.amazon.com/Science-Behind-Squalene-Human-Antioxidant/dp/1890412953) seems much less appropriate than PubMed links.
(opinion) The whole section reads like a supplement proponent trying to validate their own use of squalene while still clinging to the belief that 'squalene == bad' and I think the whole section needs to be purged or rewritten. (/opinion) Contributions/64.201.177.59 ([[User talk:|talk]]) 15:19, 17 November 2009 (UTC)
Apparently, this compound is found in human vaginal fluids in appreciably higher concentrations than what humans of both sexes use in Vitamin D and cholesterol synthesis. At least, it sounds that way here [5]. The Mysterious El Willstro ( talk) 06:20, 27 June 2010 (UTC)
Swedish and finnish studies have found a signifikant increase of narcolepsia in children who where vaccinated with pandemrix durind the swineflu. They claim that the squalene is the cause. —Preceding unsigned comment added by 81.226.64.67 ( talk) 06:01, 30 March 2011 (UTC)
The value of the melting point is reported as either -75 °C or -5 °C in many sources. The -75 value seems dubiously low in comparison to other long chain hydrocarbons, but it is reported in normally reliable secondary sources including the Merck Index. The precise value of -4.8 to -5.2 °C reported in the 1974 Angewandte Chemie paper seems the most reliable in my opinion, so I have put that one in the chembox. -- Ed ( Edgar181) 20:09, 3 April 2013 (UTC)
The structures of farnesyl pyrophosphate are missing an O in the pyrophosphate (between the two phosphorus atoms). 69.72.92.71 ( talk) 06:32, 22 December 2015 (UTC)
The comment(s) below were originally left at Talk:Squalene/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.
It mentions squalene being related to Gulf War syndrome but I cannot find any scientific literature to back this up, only sites that have poor credibility. "obtained for commercial purposes primarily from shark liver oil (hence its name)" Maybe I'm missing something, but to me it's not clear how the name "squalene" is related to squalene's production from shark liver oil. Etymologically, I mean. |
Substituted at 06:46, 30 April 2016 (UTC)
Mercola is claiming that up to a half a million sharks will be killed to make enough squalene to create “satisfy a global supply of squalene-containing vaccines”. He quotes from a New Zealand Herald article which quotes the “California-based group Shark Allies”.
If this is true, I will add a few sentences about how the manufacture of squalene has an impact on shark populations.
I don’t know what percent of the worldwide shock population is impacted?
Is there an alternative to extracting squalene from dead sharks?
https://principia-scientific.com/a-half-million-sharks-to-be-killed-for-covid-19-vaccine/ Phersh ( talk) 02:22, 10 October 2020 (UTC)