From Wikipedia, the free encyclopedia

Proposed changes

Information to be added or removed: Remove: Commercialization Section Explanation of issue: Information is out of date (2016 reference) References supporting change: URL sited (footnote 4) cannot be accessed and is significantly out of date DaveGancarz ( talk) 03:13, 3 December 2020 (UTC) reply

Updated. — soupvector ( talk) 01:17, 4 December 2020 (UTC) reply

Proposed changes

Information to be added or removed: REMOVE under Section: Regulatory Information, the subsection: Phase III Clinical Trials (entire subsection to be removed) Explanation of issue: Information is significantly out of date - reference url is from 2016 and can no longer be accessed via the page References supporting change: Referenced source is both out of date and no longer accessible on the page (footnote 4) DaveGancarz ( talk) 03:16, 3 December 2020 (UTC) reply

Updated. — soupvector ( talk) 01:18, 4 December 2020 (UTC) reply

COI (and other) issues

There appears to be some issues with this page, including COI/NPOV issues. For example, even though this is an article about a medical drug (and so I assume is under the more stringent sourcing requirements for medical articles), many of the references don't appear reliable at all. Refs #3, #5, #6, and #8 (as of the current article) are press releases from the drug's manufacturer; ref #4 is a Google docs that doesn't seem to load; ref #7 doesn't mention the drug at all; ref #9 appears to be to an NHS intranet that you need a login for. I don't think this would even be good enough for a non-medical article - that's why I added {{ More medical citations needed}}. In terms of my COI concerns: there seem to be some previous editors of the article who may work for Summit Therapeutics (the manufacturer), and aren't following the {{ request edit}} process, as has been done in the sections above. Therefore, this may not follow the NPOV policy completely - eg: in the lead where it says that the drug's "mechanism of action "remains to be fully determined", it is then followed by a quote from the manufacturer saying that they believe it works. Seagull123 Φ 17:22, 3 December 2020 (UTC) reply

I posted a notice on Wikipedia talk:WikiProject Medicine because of the request edit template. I agree that this article needs a clean up because of WP:PROMO and WP:PUFF, and I haven't even looked at the sources yet. I hope someone from WP Med will give some guidance on how to fix up this article and if the request edit should be included. Z1720 ( talk) 22:18, 3 December 2020 (UTC) reply
I've done some cleanup and added information from a nice review article (Cho 2019). More work can be done, but this is still an investigational agent. — soupvector ( talk) 01:23, 4 December 2020 (UTC) reply

Proposed changes

Information to be added or removed: In the last sentence of the article, edit to the following: As of 2020, two Phase II trials have been completed.[4] Two Phase III trials are currently in process by Summit Therapeutics. [1] Explanation of issue: Current text states indicates information from 2019 (referring to planned phase III; these trials are in process, as described by the NIH's website (url included below). References supporting change: https://clinicaltrials.gov/ct2/show/NCT03595566 DaveGancarz ( talk) 03:13, 4 December 2020 (UTC) reply

Updated. TompaDompa ( talk) 20:17, 7 December 2020 (UTC) reply

References

From Wikipedia, the free encyclopedia

Proposed changes

Information to be added or removed: Remove: Commercialization Section Explanation of issue: Information is out of date (2016 reference) References supporting change: URL sited (footnote 4) cannot be accessed and is significantly out of date DaveGancarz ( talk) 03:13, 3 December 2020 (UTC) reply

Updated. — soupvector ( talk) 01:17, 4 December 2020 (UTC) reply

Proposed changes

Information to be added or removed: REMOVE under Section: Regulatory Information, the subsection: Phase III Clinical Trials (entire subsection to be removed) Explanation of issue: Information is significantly out of date - reference url is from 2016 and can no longer be accessed via the page References supporting change: Referenced source is both out of date and no longer accessible on the page (footnote 4) DaveGancarz ( talk) 03:16, 3 December 2020 (UTC) reply

Updated. — soupvector ( talk) 01:18, 4 December 2020 (UTC) reply

COI (and other) issues

There appears to be some issues with this page, including COI/NPOV issues. For example, even though this is an article about a medical drug (and so I assume is under the more stringent sourcing requirements for medical articles), many of the references don't appear reliable at all. Refs #3, #5, #6, and #8 (as of the current article) are press releases from the drug's manufacturer; ref #4 is a Google docs that doesn't seem to load; ref #7 doesn't mention the drug at all; ref #9 appears to be to an NHS intranet that you need a login for. I don't think this would even be good enough for a non-medical article - that's why I added {{ More medical citations needed}}. In terms of my COI concerns: there seem to be some previous editors of the article who may work for Summit Therapeutics (the manufacturer), and aren't following the {{ request edit}} process, as has been done in the sections above. Therefore, this may not follow the NPOV policy completely - eg: in the lead where it says that the drug's "mechanism of action "remains to be fully determined", it is then followed by a quote from the manufacturer saying that they believe it works. Seagull123 Φ 17:22, 3 December 2020 (UTC) reply

I posted a notice on Wikipedia talk:WikiProject Medicine because of the request edit template. I agree that this article needs a clean up because of WP:PROMO and WP:PUFF, and I haven't even looked at the sources yet. I hope someone from WP Med will give some guidance on how to fix up this article and if the request edit should be included. Z1720 ( talk) 22:18, 3 December 2020 (UTC) reply
I've done some cleanup and added information from a nice review article (Cho 2019). More work can be done, but this is still an investigational agent. — soupvector ( talk) 01:23, 4 December 2020 (UTC) reply

Proposed changes

Information to be added or removed: In the last sentence of the article, edit to the following: As of 2020, two Phase II trials have been completed.[4] Two Phase III trials are currently in process by Summit Therapeutics. [1] Explanation of issue: Current text states indicates information from 2019 (referring to planned phase III; these trials are in process, as described by the NIH's website (url included below). References supporting change: https://clinicaltrials.gov/ct2/show/NCT03595566 DaveGancarz ( talk) 03:13, 4 December 2020 (UTC) reply

Updated. TompaDompa ( talk) 20:17, 7 December 2020 (UTC) reply

References


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