![]() | The contents of the Topical prednisolone page were merged into Prednisolone on 25 February 2023. For the contribution history and old versions of the redirected page, please see its history; for the discussion at that location, see its talk page. |
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This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available
on the course page. Student editor(s):
Szetoc 16,
Rduong16,
Pharming16. Peer reviewers:
Hp15elephants,
Gyang15,
Chiucc15.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 07:07, 17 January 2022 (UTC)
Most recent edit added side effects taken from the medication factsheet that came with the prednisolone I've just been prescribed. 212.139.98.72 20:04, 2 September 2007 (UTC)
Can anyone shed some light on why prednisolone is a banned substance for athletes? Anabolic steroids I obviously understand, but how would prednisolone enhance performance? 24.21.221.225 ( talk) 19:48, 25 January 2008 (UTC)
Since prednisolone is the active metabolite of prednisone and is only formed at the liver then isn't it prednisone that has the bitter taste "that makes it difficult to administer to children"? The line concerned should be removed from this article and transferred to the prednisone article. Meltyman ( talk) 08:14, 17 May 2008 (UTC)
A recently obtained (7/26/2011) drug information sheet from a local branch of a nationwide pharmacy lists under cautions:
"Corticosteroid medicines may affect growth rate in children and adolescents in some instances." One presumes this is a long course.
Consultation with a doctor before being immunized while on a course of Prednisolone.
Is excreted in breast milk.
Advises physician consultation for use during pregnancy.
66.92.11.54 ( talk) 02:29, 27 July 2011 (UTC)Literate Dad 67.142.181.23 ( talk) 09:42, 25 October 2012 (UTC)
Infections under Investigation [1]in Patients Exposed to NECC [2]Products Other than the 3 Contaminated Lots of Methylprednisolone Acetate
Meningitis, Spinal or Paraspinal Infection A person who developed any of the following after epidural or paraspinal2 injection after May 21, 2012 of an NECC product:
Meningitis of unknown etiology. Osteomyelitis, abscess or other infection (e.g., soft tissue infection) of unknown etiology, in the spinal or paraspinal structures at or near the site of injection. Fungal Infection of Interest A person who developed fungal infection in a normally sterile site4 with laboratory evidence by culture, histopathology, molecular (e.g. NAAT or PCR), or positive galactomannan test following administration of an NECC product into a sterile site after May 21, 2012.
1.Products from NECC other than the 3 contaminated lots (05212012@68, 06292012@26, 08102012@51) of methylprednisolone acetate.
2.Paraspinal injections include, but are not limited to, spinal facet joint injection, sacroiliac joint injection,or spinal or paraspinal nerve root/ganglion block.
3.Clinically diagnosed meningitis with one or more of the following symptoms: headache, fever, stiff neck, or photophobia, in addition to a CSF profile showing pleocytosis (>5 white blood cells, adjusting for presence of red blood cells by subtracting 1 white blood cell for every 500 red blood cells present) regardless of glucose or protein levels.
4.Normally sterile sites include blood, CSF, pleural fluid, peritoneal fluid, pericardial fluid, surgical aspirate, bone, joint fluid, or internal body site (e.g., eye, lymph node or brain).
[3] [4] Division of Healthcare Quality Promotion (DHQP) 67.142.181.23 ( talk) 08:22, 25 October 2012 (UTC)
67.142.181.23 ( talk) 09:15, 25 October 2012 (UTC)
67.142.181.23 ( talk) 09:34, 25 October 2012 (UTC) 67.142.181.23 ( talk) 09:36, 25 October 2012 (UTC) 67.142.181.23 ( talk) 09:42, 25 October 2012 (UTC)
References
We edited the content explaining the mechanism of action for prednisolone. There was no reliable way of cross checking the outdated references so we used more recent data from a secondary source to explain this section. We also updated the potential side effects that may occur with Prednisolone. In addition, we found review articles to support some statements made what prednisolone may be used for. — Preceding unsigned comment added by Pharming16 ( talk • contribs) 19:25, 5 November 2015 (UTC)
The article does contain a neutral view. The cited references are verifiable. Our recommendations include: Pros: Good, clear explanation of the mechanism of action for prednisolone. There are high quality references for mechanism of action. Cons: The lead should include other general information about prednisolone, such as it’s most common/major indications and common side effects. It wouldn’t hurt to put references for all of the adverse effects or to reference that a certain source covers all of the adverse effects. I can’t seem to find a source for your image in the MOA section. The paper you used for the text is great, but it’s hard to be certain the image reflects that. — Preceding unsigned comment added by Gyang15 ( talk • contribs) 02:59, 9 November 2015 (UTC)
I'm not a medic or pharmacist so hesitate to change the lead sentence here myself, but could I suggest that the link to Corticosteroid shouldn't be piped? As a non-specialist, I didn't know whether "steroid medication" implied "corticosteroid" or not. Perhaps: "Prednisolone is a corticosteroid medication used ..." would be clearer? Pam D 21:53, 29 January 2018 (UTC)
"Prednisolone was discovered and approved for medical use in 1955.[7]" - But [7] (Kim K, Roh JK, Wee H, Kim C (2016). Cancer Drug Discovery: Science and History) describes Prednisone, which is supposed to be a different drug and specifically mentioned in the "Not to be confused with" note at the beginning. — Preceding unsigned comment added by Avatar(DS) ( talk • contribs) 06:49, 7 April 2020 (UTC)
I have included the following warning from my GP as a matter of urgency. (It is often prescribed as an emergency pack which can be taken when needed without having to wait for a clinic appointment) If someone can find a published reference to quote it would be gratefully received.
Use of Prednisolone as an anti-inflammatory, for instance in COPD exacerbation, is contraindicated if the person is infected with COVID-19 or suspects they may be. — Preceding unsigned comment added by Chevin ( talk • contribs)
Topical prednisolone is an unnecessary fork of prednisolone. — rsjaffe 🗣️ 03:57, 25 May 2022 (UTC)
![]() | The contents of the Topical prednisolone page were merged into Prednisolone on 25 February 2023. For the contribution history and old versions of the redirected page, please see its history; for the discussion at that location, see its talk page. |
This is the
talk page for discussing improvements to the
Prednisolone article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||||||||||||
|
![]() | It is requested that an image or photograph of Prednisolone be
included in this article to
improve its quality. Please replace this template with a more specific
media request template where possible.
The Free Image Search Tool or Openverse Creative Commons Search may be able to locate suitable images on Flickr and other web sites. |
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Prednisolone.
|
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available
on the course page. Student editor(s):
Szetoc 16,
Rduong16,
Pharming16. Peer reviewers:
Hp15elephants,
Gyang15,
Chiucc15.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 07:07, 17 January 2022 (UTC)
Most recent edit added side effects taken from the medication factsheet that came with the prednisolone I've just been prescribed. 212.139.98.72 20:04, 2 September 2007 (UTC)
Can anyone shed some light on why prednisolone is a banned substance for athletes? Anabolic steroids I obviously understand, but how would prednisolone enhance performance? 24.21.221.225 ( talk) 19:48, 25 January 2008 (UTC)
Since prednisolone is the active metabolite of prednisone and is only formed at the liver then isn't it prednisone that has the bitter taste "that makes it difficult to administer to children"? The line concerned should be removed from this article and transferred to the prednisone article. Meltyman ( talk) 08:14, 17 May 2008 (UTC)
A recently obtained (7/26/2011) drug information sheet from a local branch of a nationwide pharmacy lists under cautions:
"Corticosteroid medicines may affect growth rate in children and adolescents in some instances." One presumes this is a long course.
Consultation with a doctor before being immunized while on a course of Prednisolone.
Is excreted in breast milk.
Advises physician consultation for use during pregnancy.
66.92.11.54 ( talk) 02:29, 27 July 2011 (UTC)Literate Dad 67.142.181.23 ( talk) 09:42, 25 October 2012 (UTC)
Infections under Investigation [1]in Patients Exposed to NECC [2]Products Other than the 3 Contaminated Lots of Methylprednisolone Acetate
Meningitis, Spinal or Paraspinal Infection A person who developed any of the following after epidural or paraspinal2 injection after May 21, 2012 of an NECC product:
Meningitis of unknown etiology. Osteomyelitis, abscess or other infection (e.g., soft tissue infection) of unknown etiology, in the spinal or paraspinal structures at or near the site of injection. Fungal Infection of Interest A person who developed fungal infection in a normally sterile site4 with laboratory evidence by culture, histopathology, molecular (e.g. NAAT or PCR), or positive galactomannan test following administration of an NECC product into a sterile site after May 21, 2012.
1.Products from NECC other than the 3 contaminated lots (05212012@68, 06292012@26, 08102012@51) of methylprednisolone acetate.
2.Paraspinal injections include, but are not limited to, spinal facet joint injection, sacroiliac joint injection,or spinal or paraspinal nerve root/ganglion block.
3.Clinically diagnosed meningitis with one or more of the following symptoms: headache, fever, stiff neck, or photophobia, in addition to a CSF profile showing pleocytosis (>5 white blood cells, adjusting for presence of red blood cells by subtracting 1 white blood cell for every 500 red blood cells present) regardless of glucose or protein levels.
4.Normally sterile sites include blood, CSF, pleural fluid, peritoneal fluid, pericardial fluid, surgical aspirate, bone, joint fluid, or internal body site (e.g., eye, lymph node or brain).
[3] [4] Division of Healthcare Quality Promotion (DHQP) 67.142.181.23 ( talk) 08:22, 25 October 2012 (UTC)
67.142.181.23 ( talk) 09:15, 25 October 2012 (UTC)
67.142.181.23 ( talk) 09:34, 25 October 2012 (UTC) 67.142.181.23 ( talk) 09:36, 25 October 2012 (UTC) 67.142.181.23 ( talk) 09:42, 25 October 2012 (UTC)
References
We edited the content explaining the mechanism of action for prednisolone. There was no reliable way of cross checking the outdated references so we used more recent data from a secondary source to explain this section. We also updated the potential side effects that may occur with Prednisolone. In addition, we found review articles to support some statements made what prednisolone may be used for. — Preceding unsigned comment added by Pharming16 ( talk • contribs) 19:25, 5 November 2015 (UTC)
The article does contain a neutral view. The cited references are verifiable. Our recommendations include: Pros: Good, clear explanation of the mechanism of action for prednisolone. There are high quality references for mechanism of action. Cons: The lead should include other general information about prednisolone, such as it’s most common/major indications and common side effects. It wouldn’t hurt to put references for all of the adverse effects or to reference that a certain source covers all of the adverse effects. I can’t seem to find a source for your image in the MOA section. The paper you used for the text is great, but it’s hard to be certain the image reflects that. — Preceding unsigned comment added by Gyang15 ( talk • contribs) 02:59, 9 November 2015 (UTC)
I'm not a medic or pharmacist so hesitate to change the lead sentence here myself, but could I suggest that the link to Corticosteroid shouldn't be piped? As a non-specialist, I didn't know whether "steroid medication" implied "corticosteroid" or not. Perhaps: "Prednisolone is a corticosteroid medication used ..." would be clearer? Pam D 21:53, 29 January 2018 (UTC)
"Prednisolone was discovered and approved for medical use in 1955.[7]" - But [7] (Kim K, Roh JK, Wee H, Kim C (2016). Cancer Drug Discovery: Science and History) describes Prednisone, which is supposed to be a different drug and specifically mentioned in the "Not to be confused with" note at the beginning. — Preceding unsigned comment added by Avatar(DS) ( talk • contribs) 06:49, 7 April 2020 (UTC)
I have included the following warning from my GP as a matter of urgency. (It is often prescribed as an emergency pack which can be taken when needed without having to wait for a clinic appointment) If someone can find a published reference to quote it would be gratefully received.
Use of Prednisolone as an anti-inflammatory, for instance in COPD exacerbation, is contraindicated if the person is infected with COVID-19 or suspects they may be. — Preceding unsigned comment added by Chevin ( talk • contribs)
Topical prednisolone is an unnecessary fork of prednisolone. — rsjaffe 🗣️ 03:57, 25 May 2022 (UTC)