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This article was categorized based on scheme outlined at WP:DERM:CAT. kilbad ( talk) 02:40, 18 January 2009 (UTC)
I removed the "occurring in the hair" part, as piebaldism refers not only to abnormalities in hair colouring but also in skin pigmentation - see references. Perhaps a fuller definition might see "occurring in hair and skin" but the definition in the article seems to be the common one. DI Ramekin 08:55, 22 March 2007 (UTC)
I know very little about this, but it seems as though Piebaldism is a type of Leucism? Should someone write up a line or two on the distinction between these 2? And, I've heard this can be caused by Mosaicism and Chimerism, again I know nothing about it but perhaps it should be included in the article.
Also, I'm going to go ahead and add a picture of a piebald snake. Quincyjo ( talk) 22:29, 25 May 2013 (UTC)
There is a separate article for piebald in non-humans. Not sure why they have to be separate. The conditions are the same. Student7 ( talk) 19:19, 29 August 2015 (UTC)
This article states: "Piebaldism is unrelated to conditions such as vitiligo or poliosis."
The article on Poliosis states: "Poliosis occurs in several genetic syndromes such as piebaldism, Waardenburg syndrome, neurofibromatosis type I, and tuberous sclerosis."
This is contradictory. Which article is correct? — Preceding unsigned comment added by Filobel ( talk • contribs) 21:50, 6 December 2021 (UTC)
This article states, "Piebaldism differs from albinism in that the affected cells maintain the ability to produce pigment but have that specific function turned off. In albinism the cells lack the ability to produce pigment altogether."
In contradiction to this different sources state that in Piebaldism the affected skin areas lack melanin producing cells (melanocytes).
E.g. the following review from 2012:
Piebaldism: A brief report and review of the literature Indian Dermatol Online J. 2012 May-Aug; 3(2): 144–147. doi: 10.4103/2229-5178.96722 [1]
"Piebaldism is a rare autosomal dominant disorder characterized by the congenital absence of melanocytes in affected areas of the skin and hair due to mutations of the c-kit gene, located on Chromosome 4q12, which affects the differentiation and migration of melanoblasts from the neural crest during the embryonic life."
Croak!ichi ( talk) 20:21, 31 May 2022 (UTC)
This article is rated Start-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Piebaldism.
|
It is requested that a photograph be
included in this article to
improve its quality.
The external tool WordPress Openverse may be able to locate suitable images on Flickr and other web sites. |
This article was categorized based on scheme outlined at WP:DERM:CAT. kilbad ( talk) 02:40, 18 January 2009 (UTC)
I removed the "occurring in the hair" part, as piebaldism refers not only to abnormalities in hair colouring but also in skin pigmentation - see references. Perhaps a fuller definition might see "occurring in hair and skin" but the definition in the article seems to be the common one. DI Ramekin 08:55, 22 March 2007 (UTC)
I know very little about this, but it seems as though Piebaldism is a type of Leucism? Should someone write up a line or two on the distinction between these 2? And, I've heard this can be caused by Mosaicism and Chimerism, again I know nothing about it but perhaps it should be included in the article.
Also, I'm going to go ahead and add a picture of a piebald snake. Quincyjo ( talk) 22:29, 25 May 2013 (UTC)
There is a separate article for piebald in non-humans. Not sure why they have to be separate. The conditions are the same. Student7 ( talk) 19:19, 29 August 2015 (UTC)
This article states: "Piebaldism is unrelated to conditions such as vitiligo or poliosis."
The article on Poliosis states: "Poliosis occurs in several genetic syndromes such as piebaldism, Waardenburg syndrome, neurofibromatosis type I, and tuberous sclerosis."
This is contradictory. Which article is correct? — Preceding unsigned comment added by Filobel ( talk • contribs) 21:50, 6 December 2021 (UTC)
This article states, "Piebaldism differs from albinism in that the affected cells maintain the ability to produce pigment but have that specific function turned off. In albinism the cells lack the ability to produce pigment altogether."
In contradiction to this different sources state that in Piebaldism the affected skin areas lack melanin producing cells (melanocytes).
E.g. the following review from 2012:
Piebaldism: A brief report and review of the literature Indian Dermatol Online J. 2012 May-Aug; 3(2): 144–147. doi: 10.4103/2229-5178.96722 [1]
"Piebaldism is a rare autosomal dominant disorder characterized by the congenital absence of melanocytes in affected areas of the skin and hair due to mutations of the c-kit gene, located on Chromosome 4q12, which affects the differentiation and migration of melanoblasts from the neural crest during the embryonic life."
Croak!ichi ( talk) 20:21, 31 May 2022 (UTC)