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It seems that recent publications argue otherwise.
A nice article reviewing that subject can be found here: http://www.wired.com/wiredscience/2012/08/pertussis-vax-effectiveness/ — Preceding unsigned comment added by 93.172.40.31 ( talk) 15:27, 15 January 2013 (UTC)
What if a healthy adult takes BOTH vaccines? Is the efficacy improved? And please name some vaccine brands that are available for adult consumers to buy!! 91.155.24.127 ( talk) 17:43, 25 October 2017 (UTC)
The current wikitext says: As of 2013 there are five acellular TDaP/Tdap vaccines licensed for use in USA: Infanrix and DAPTACEL – for children, Boostrix and ADACEL – for adolescents and adults..... unless I can't count, only four are listed (and there are only four in the following table as well). Is the "five" wrong, is there one missing, or does one of the ones mentioned really count as two? Also the source provided is from 2009, not 2013 as suggested by the text. I've fixed these issues.
The FDA site [1] lists 4 vaccines, one having 3 brand names, one of which (Tripedia) is discontinued. This gives us 5: Infantrix, Daptacel, Pediatrix, Kinrix and Pentacel... unless there's a good reason not to we should be using this more up to date info. I note that some of these have Hep B, Polio and/or HaemophilusB added as well, so perhaps we need more columns on the table?
Tobus ( talk) 23:13, 9 January 2014 (UTC)
https://www.cdc.gov/vaccines/vpd/dtap-tdap-td/hcp/about-vaccine.html
Page last reviewed: January 22, 2020
The Food and Drug Administration (FDA) licensed 12 vaccines for use in the United States to help protect against diphtheria and tetanus. 9 of these vaccines also help protect against pertussis.
In studies demonstrating the efficacy of the pertussis component for children who get all 5 doses on schedule, DTaP fully protects:
QUESTION: how could an adult get 98% protection? Off-label DTaP vaccines for adults?
In studies demonstrating the efficacy of the pertussis component, Tdap fully protects:
In studies demonstrating the efficacy of the pertussis component when women get Tdap during pregnancy, the vaccine prevents:
91.159.188.74 ( talk) 01:55, 7 February 2022 (UTC)
A contribution of mine was recently reverted, on the grounds that it was insufficiently cited by Google Scholar. It was from a study in a peer-reviewed journal, and I included a secondary source that provided interpretation of the study. It seems relevant to the article, and I was careful to phrase everything such that no undue weight was being applied. This information seems helpful to readers seeking unbiased information on the topic of the article, and it's not clear to my why it should be excluded. -- Outdowands ( talk) 23:45, 6 February 2017 (UTC)
Chicken animal study, was it even about pertussis vaccine? http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198
It might be that some vaccines cause Less harmful microbes and some vaccines More harmful. If a human eats a lot of xylitol, caries causing S.mustans bacteria mutate so that they become resistant to xylitol, BUT these mutated S.mustans bacteria are less cariogenic = cause less tooth decay! 91.155.24.127 ( talk) 17:24, 2 November 2017 (UTC)
2 interesting studies:
1)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197970
Acellular pertussis vaccines effectiveness over time: A systematic review, meta-analysis and modeling study
Published: June 18, 2018
Observational VE studies of boosting failed to recognize that they were measuring relative, not absolute, VE and the absolute VE in the boosted population is better than appreciated.
We estimate initial childhood series absolute VE is 91% (95% CI: 87% to 95%) and declines at 9.6% annually.
Initial relative VE after adolescent boosting is 70% (95% CI: 54% to 86%) and declines at 45.3% annually.
Initial absolute VE after adolescent boosting is 85% (95% CI: 84% to 86%) and declines at 11.7% (95% CI: 11.1% to 12.3%) annually.
2)
A 5-component pertussis vaccine might be more efficient, than with less components:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349526/
Acellular Pertussis Vaccine Components: Today and Tomorrow
Published online 2020 May 13.
This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Pertussis vaccine.
|
It seems that recent publications argue otherwise.
A nice article reviewing that subject can be found here: http://www.wired.com/wiredscience/2012/08/pertussis-vax-effectiveness/ — Preceding unsigned comment added by 93.172.40.31 ( talk) 15:27, 15 January 2013 (UTC)
What if a healthy adult takes BOTH vaccines? Is the efficacy improved? And please name some vaccine brands that are available for adult consumers to buy!! 91.155.24.127 ( talk) 17:43, 25 October 2017 (UTC)
The current wikitext says: As of 2013 there are five acellular TDaP/Tdap vaccines licensed for use in USA: Infanrix and DAPTACEL – for children, Boostrix and ADACEL – for adolescents and adults..... unless I can't count, only four are listed (and there are only four in the following table as well). Is the "five" wrong, is there one missing, or does one of the ones mentioned really count as two? Also the source provided is from 2009, not 2013 as suggested by the text. I've fixed these issues.
The FDA site [1] lists 4 vaccines, one having 3 brand names, one of which (Tripedia) is discontinued. This gives us 5: Infantrix, Daptacel, Pediatrix, Kinrix and Pentacel... unless there's a good reason not to we should be using this more up to date info. I note that some of these have Hep B, Polio and/or HaemophilusB added as well, so perhaps we need more columns on the table?
Tobus ( talk) 23:13, 9 January 2014 (UTC)
https://www.cdc.gov/vaccines/vpd/dtap-tdap-td/hcp/about-vaccine.html
Page last reviewed: January 22, 2020
The Food and Drug Administration (FDA) licensed 12 vaccines for use in the United States to help protect against diphtheria and tetanus. 9 of these vaccines also help protect against pertussis.
In studies demonstrating the efficacy of the pertussis component for children who get all 5 doses on schedule, DTaP fully protects:
QUESTION: how could an adult get 98% protection? Off-label DTaP vaccines for adults?
In studies demonstrating the efficacy of the pertussis component, Tdap fully protects:
In studies demonstrating the efficacy of the pertussis component when women get Tdap during pregnancy, the vaccine prevents:
91.159.188.74 ( talk) 01:55, 7 February 2022 (UTC)
A contribution of mine was recently reverted, on the grounds that it was insufficiently cited by Google Scholar. It was from a study in a peer-reviewed journal, and I included a secondary source that provided interpretation of the study. It seems relevant to the article, and I was careful to phrase everything such that no undue weight was being applied. This information seems helpful to readers seeking unbiased information on the topic of the article, and it's not clear to my why it should be excluded. -- Outdowands ( talk) 23:45, 6 February 2017 (UTC)
Chicken animal study, was it even about pertussis vaccine? http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198
It might be that some vaccines cause Less harmful microbes and some vaccines More harmful. If a human eats a lot of xylitol, caries causing S.mustans bacteria mutate so that they become resistant to xylitol, BUT these mutated S.mustans bacteria are less cariogenic = cause less tooth decay! 91.155.24.127 ( talk) 17:24, 2 November 2017 (UTC)
2 interesting studies:
1)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197970
Acellular pertussis vaccines effectiveness over time: A systematic review, meta-analysis and modeling study
Published: June 18, 2018
Observational VE studies of boosting failed to recognize that they were measuring relative, not absolute, VE and the absolute VE in the boosted population is better than appreciated.
We estimate initial childhood series absolute VE is 91% (95% CI: 87% to 95%) and declines at 9.6% annually.
Initial relative VE after adolescent boosting is 70% (95% CI: 54% to 86%) and declines at 45.3% annually.
Initial absolute VE after adolescent boosting is 85% (95% CI: 84% to 86%) and declines at 11.7% (95% CI: 11.1% to 12.3%) annually.
2)
A 5-component pertussis vaccine might be more efficient, than with less components:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349526/
Acellular Pertussis Vaccine Components: Today and Tomorrow
Published online 2020 May 13.