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This article is written in British English, which has its own spelling conventions (colour, travelled, centre, defence, artefact, analyse) and some terms that are used in it may be different or absent from other varieties of English. According to the relevant style guide, this should not be changed without broad consensus. |
Penicillin desensitization was nominated for deletion. The discussion was closed on 25 May 2017 with a consensus to merge. Its contents were merged into Penicillin. The original page is now a redirect to this page. For the contribution history and old versions of the redirected article, please see its history; for its talk page, see here. |
A fact from this article was featured on Wikipedia's Main Page in the On this day section on September 28, 2008, September 28, 2009, September 28, 2010, September 28, 2011, September 28, 2013, and September 28, 2019. |
So staphylococcus Aureus is mentioned multiple times in this article, yet despite a few asides about Antistaphylococcal antibiotics the impression is strongly given that penicillin or beta lactams in general would be appropriate for treating staph. Case in point, under Bacterial Susceptibility, staph is included whereas especial mention is given to the fact that Neisseria may not be susceptible due to drug resistance.
Currently completing medicine and we've been told that penicillin is basically never appropriate for staph due to beta lactamase being present essentially 100% of the time (hence the anti-staphylococcal antibiotics), and yet conversely penicillin is still mostly okay for Neisseria.
Further reading suggests that the genetic uniquity of beta lactamase (due to being on a transposable element and intense selection pressure) had occurred by the late sixties. Anyway, so penicillin hasn't been appropriate for staph for almost 60 years, so I'm curious why this article gives the impression it is, and yet makes clear the much hazier resistance issues surrounding Neisseria.
Suggest edit for clarity, and unless a source is provided a redo of the susceptibility list to remove staph (include in the preamble if you wish). The susceptibility list I have suggests that the main ones for penicillin of clinical note are Strep, enterococci, Neisseria, and clostridium.
Cheers, Cyst11 ( talk) 05:51, 18 May 2023 (UTC)
The antibiotic properties of penicillin had been researched for more than a decade in Clodomiro Picado's laboratory before Fleming's fortuitous "discovery." I ask that you please correct the information or at least add a comment making it clear that there are "two discoverers" of penicillin.
Source: https://www.bbc.com/mundo/noticias-53953810 — Preceding unsigned comment added by Consumer999 ( talk • contribs) 21:53, 21 December 2023 (UTC)
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change description of penicillin's discovery to include words 'by chance'. the reference in support of this edit suggestion is: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403050/ 49.181.238.198 ( talk) 00:21, 6 May 2024 (UTC)
This is the
talk page for discussing improvements to the
Penicillin article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
Archives: 1Auto-archiving period: 90 days |
This
level-4 vital article is rated B-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||||||||||||||||||||
|
This article is written in British English, which has its own spelling conventions (colour, travelled, centre, defence, artefact, analyse) and some terms that are used in it may be different or absent from other varieties of English. According to the relevant style guide, this should not be changed without broad consensus. |
Penicillin desensitization was nominated for deletion. The discussion was closed on 25 May 2017 with a consensus to merge. Its contents were merged into Penicillin. The original page is now a redirect to this page. For the contribution history and old versions of the redirected article, please see its history; for its talk page, see here. |
A fact from this article was featured on Wikipedia's Main Page in the On this day section on September 28, 2008, September 28, 2009, September 28, 2010, September 28, 2011, September 28, 2013, and September 28, 2019. |
So staphylococcus Aureus is mentioned multiple times in this article, yet despite a few asides about Antistaphylococcal antibiotics the impression is strongly given that penicillin or beta lactams in general would be appropriate for treating staph. Case in point, under Bacterial Susceptibility, staph is included whereas especial mention is given to the fact that Neisseria may not be susceptible due to drug resistance.
Currently completing medicine and we've been told that penicillin is basically never appropriate for staph due to beta lactamase being present essentially 100% of the time (hence the anti-staphylococcal antibiotics), and yet conversely penicillin is still mostly okay for Neisseria.
Further reading suggests that the genetic uniquity of beta lactamase (due to being on a transposable element and intense selection pressure) had occurred by the late sixties. Anyway, so penicillin hasn't been appropriate for staph for almost 60 years, so I'm curious why this article gives the impression it is, and yet makes clear the much hazier resistance issues surrounding Neisseria.
Suggest edit for clarity, and unless a source is provided a redo of the susceptibility list to remove staph (include in the preamble if you wish). The susceptibility list I have suggests that the main ones for penicillin of clinical note are Strep, enterococci, Neisseria, and clostridium.
Cheers, Cyst11 ( talk) 05:51, 18 May 2023 (UTC)
The antibiotic properties of penicillin had been researched for more than a decade in Clodomiro Picado's laboratory before Fleming's fortuitous "discovery." I ask that you please correct the information or at least add a comment making it clear that there are "two discoverers" of penicillin.
Source: https://www.bbc.com/mundo/noticias-53953810 — Preceding unsigned comment added by Consumer999 ( talk • contribs) 21:53, 21 December 2023 (UTC)
This
edit request has been answered. Set the |answered= or |ans= parameter to no to reactivate your request. |
change description of penicillin's discovery to include words 'by chance'. the reference in support of this edit suggestion is: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403050/ 49.181.238.198 ( talk) 00:21, 6 May 2024 (UTC)