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The article states that SCUBA divers use up to 100% oxygen. I'd like to see a cite for that; it makes no sense since it would be poison at a fairly low depth.
Learjeff ( talk) 16:48, 17 March 2013 (UTC)
I understand the distinction between oxygen partial pressure (e.g. 20% af 15 psi is 3 psi O2 partial pressure) and concentration of oxygen (oxygen percentage of inhaled atmosphere), but the article doesn't seem to. It bounces from one to the other as though they were somehow commensurate, which isn't so (e.g., 100% O2 at 5 psi and 25% O2 at 20 psi both produce an O2 partial pressure of 5 psi). If the partial pressure of O2 is relevant in some contexts and its atmospheric concentration is relevant in others, then some indication should be given of which is relevant where. — Preceding unsigned comment added by 199.223.125.164 ( talk) 05:32, 13 May 2013 (UTC)
Current text reads:
The statement about 50% partial pressure reads like an introduction, but the begins with clause in the next sentence contradicts it. These do not seem to be from the same source, suggesting the first statement is without source. Does someone have an unambiguous RS telling at what point pulmonary toxicity begins? Grammar'sLittleHelper ( talk) 19:36, 7 April 2016 (UTC)
I've revisited Sfarney's multiple changes and incorporated those that will have consensus to a greater or lesser extent. I find that the remainder remove nuances (such as replacing "is usually associated with" by "causes"; replacing "coldness" with "hypothermia"), or dilute the point of the text (such as removing the statement that CNS toxicity can only occur under hyperbaric conditions), or are tautological (such as "the lungs and respiratory tract"). Please feel free to discuss further disputed changes below. -- RexxS ( talk) 10:32, 8 April 2016 (UTC)
I want to thank you both for your careful attendance to these edits, and your general improvements to the topic. Grammar'sLittleHelper ( talk) 22:42, 8 April 2016 (UTC)
From "Signs and symptoms", subsection "Central nervous system": "Central nervous system oxygen toxicity manifests as... irritability (personality changes, anxiety, confusion, etc.)." I don't think that confusion is a feature of irritability. Anxiety is borderline too. Axl ¤ [Talk] 10:00, 12 April 2016 (UTC)
Central nervous system oxygen toxicity manifests as symptoms such as visual changes (especially tunnel vision), ringing in the ears ( tinnitus), nausea, twitching (especially of the face), behavioural changes (irritability, anxiety, confusion), and dizziness.
From "Signs and symptoms", subsection "Central nervous system": "In addition, many external factors, such as underwater immersion... will decrease the time to onset of central nervous system symptoms." Is that really true? (I can see that temperature and exertion could have a bearing.) Axl ¤ [Talk] 11:00, 13 April 2016 (UTC)
In general, oxygen is better tolerated in dry, resting conditions than in wet conditions and while exercising as in diving.. (last paragraph of section "Who is Exposed to the Risk of Oxygen Toxicity?") Cheers, • • • Peter (Southwood) (talk): 08:17, 14 April 2016 (UTC)
From "Signs and symptoms", subsection "Lungs": "The radiological finding from the lungs shows inflammation and swelling ( pulmonary oedema)." Pulmonary oedema is not inflammation and swelling. Axl ¤ [Talk] 11:11, 13 April 2016 (UTC)
Radiological findings from the lungs show little change in the short term, but extended exposure leads to increasing density of lesions extending throughout both lungs.
Although there is some interest in research into possible means of delaying the onset of oxygen toxicity, there are no secondary sources indicating any significant results in humans. The small amount of research in mice and rats does show promise, but primary sources are insufficient to support biomedical claims as outlined in WP:MEDRS. We should be waiting for secondary sources to assess primary sources and draw conclusions that would then be suitable for inclusion in an article.
This is a featured article and additional sections need to comply with FA criteria, particularly compliance with MOS - in this case, WP:MEDMOS, as well as norms of writing style, such as avoidance of single sentence paragraphs. As a result, I've decided to restore the prior version before the animal studies were added. Here is the text and sources that I've removed:
== Research ==
A study in rats concluded that ketosis delays central nervous system oxygen toxicity. [1]
Some antiepileptic drugs are also hypothesised to delay onset of oxygen-induced seizures in mice. [2]
A study in mice found that biologically produced nitric oxide is part of the mechanism that causes oxygen toxicity, and that superoxide ions inhibit the oxygen-toxicity-causing role of nitric oxide. [3]
References
- ^ D'Agostino, Dominic P; Pilla, Raffaele; Held, Heather E; Landon, Carol S; Puchowicz, Michelle; Brunengraber, Henri; Ari, Csilla; Arnold, Patrick; Dean, Jay B (3 April 2013). "Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats". AJP: Regulatory, Integrative and Comparative Physiology. 304 (10): R829–R836. doi: 10.1152/ajpregu.00506.2012.
- ^ Demchenko, IT; Zhilyaev, SY; Moskvin, AN; Krivchenko, AI; Piantadosi, CA; Allen, BW (15 February 2017). "Antiepileptic drugs prevent seizures in hyperbaric oxygen: A novel model of epileptiform activity". Brain research. 1657: 347–354. PMID 28057450.
- ^ https://www.ncbi.nlm.nih.gov/pubmed/1329105 Extracellular superoxide dismutase, nitric oxide, and central nervous system O2 toxicity. by Oury TD1, Ho YS, Piantadosi CA, Crapo JD., Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9715-9.
If Anthony wishes to reinstate the text, then that should be discussed here first. I'll ask Doc James if he thinks any part of the text or sources might be usable. -- RexxS ( talk) 11:29, 11 April 2017 (UTC)
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I made the positive decision to use a minimum column width of 30em as I feel that is the best compromise between whitespace and line-wrapping for this article. That's not to say that I intended the column widths to be set to the default value for {{ Reflist}}, which is subject to change of course. If there is an rationale to use a different minimum column width, then I'm happy to discus it here. -- RexxS ( talk) 11:54, 25 March 2018 (UTC)
There are a few items I have identified as incomplete or requiring some clarification. This is normal, and does not mean the article needs to be delisted as a featured article as they are minor matters, but it is necessary to do some research to find suitable sources before making the changes. · · · Peter Southwood (talk): 06:01, 23 December 2022 (UTC)
Diving Medicine, Hyperbaric Medicine and Neonatal Medicine all have to deal with oxygen toxicity even more than Emergency Medicine. 2605:59C8:11CF:DF10:BCCB:C9FF:FE2A:B121 ( talk) 04:38, 14 June 2023 (UTC)
The article is below FA standard with regard to citations. I have tagged some places where they are needed. Could this be addressed to avoid WP:FAR? Graham Beards ( talk) 12:52, 16 November 2023 (UTC)
This is the
talk page for discussing improvements to the
Oxygen toxicity article. This is not a forum for general discussion of the article's subject. |
Article policies
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Archives: 1 |
![]() | This article is written in British English, which has its own spelling conventions (colour, travelled, centre, defence, artefact, analyse) and some terms that are used in it may be different or absent from other varieties of English. According to the relevant style guide, this should not be changed without broad consensus. |
![]() | Oxygen toxicity is a featured article; it (or a previous version of it) has been identified as one of the best articles produced by the Wikipedia community. Even so, if you can update or improve it, please do so. | ||||||||||||||||||||||||
![]() | This article appeared on Wikipedia's Main Page as Today's featured article on August 31, 2009. | ||||||||||||||||||||||||
|
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content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||||||||||||
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![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Oxygen toxicity.
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The article states that SCUBA divers use up to 100% oxygen. I'd like to see a cite for that; it makes no sense since it would be poison at a fairly low depth.
Learjeff ( talk) 16:48, 17 March 2013 (UTC)
I understand the distinction between oxygen partial pressure (e.g. 20% af 15 psi is 3 psi O2 partial pressure) and concentration of oxygen (oxygen percentage of inhaled atmosphere), but the article doesn't seem to. It bounces from one to the other as though they were somehow commensurate, which isn't so (e.g., 100% O2 at 5 psi and 25% O2 at 20 psi both produce an O2 partial pressure of 5 psi). If the partial pressure of O2 is relevant in some contexts and its atmospheric concentration is relevant in others, then some indication should be given of which is relevant where. — Preceding unsigned comment added by 199.223.125.164 ( talk) 05:32, 13 May 2013 (UTC)
Current text reads:
The statement about 50% partial pressure reads like an introduction, but the begins with clause in the next sentence contradicts it. These do not seem to be from the same source, suggesting the first statement is without source. Does someone have an unambiguous RS telling at what point pulmonary toxicity begins? Grammar'sLittleHelper ( talk) 19:36, 7 April 2016 (UTC)
I've revisited Sfarney's multiple changes and incorporated those that will have consensus to a greater or lesser extent. I find that the remainder remove nuances (such as replacing "is usually associated with" by "causes"; replacing "coldness" with "hypothermia"), or dilute the point of the text (such as removing the statement that CNS toxicity can only occur under hyperbaric conditions), or are tautological (such as "the lungs and respiratory tract"). Please feel free to discuss further disputed changes below. -- RexxS ( talk) 10:32, 8 April 2016 (UTC)
I want to thank you both for your careful attendance to these edits, and your general improvements to the topic. Grammar'sLittleHelper ( talk) 22:42, 8 April 2016 (UTC)
From "Signs and symptoms", subsection "Central nervous system": "Central nervous system oxygen toxicity manifests as... irritability (personality changes, anxiety, confusion, etc.)." I don't think that confusion is a feature of irritability. Anxiety is borderline too. Axl ¤ [Talk] 10:00, 12 April 2016 (UTC)
Central nervous system oxygen toxicity manifests as symptoms such as visual changes (especially tunnel vision), ringing in the ears ( tinnitus), nausea, twitching (especially of the face), behavioural changes (irritability, anxiety, confusion), and dizziness.
From "Signs and symptoms", subsection "Central nervous system": "In addition, many external factors, such as underwater immersion... will decrease the time to onset of central nervous system symptoms." Is that really true? (I can see that temperature and exertion could have a bearing.) Axl ¤ [Talk] 11:00, 13 April 2016 (UTC)
In general, oxygen is better tolerated in dry, resting conditions than in wet conditions and while exercising as in diving.. (last paragraph of section "Who is Exposed to the Risk of Oxygen Toxicity?") Cheers, • • • Peter (Southwood) (talk): 08:17, 14 April 2016 (UTC)
From "Signs and symptoms", subsection "Lungs": "The radiological finding from the lungs shows inflammation and swelling ( pulmonary oedema)." Pulmonary oedema is not inflammation and swelling. Axl ¤ [Talk] 11:11, 13 April 2016 (UTC)
Radiological findings from the lungs show little change in the short term, but extended exposure leads to increasing density of lesions extending throughout both lungs.
Although there is some interest in research into possible means of delaying the onset of oxygen toxicity, there are no secondary sources indicating any significant results in humans. The small amount of research in mice and rats does show promise, but primary sources are insufficient to support biomedical claims as outlined in WP:MEDRS. We should be waiting for secondary sources to assess primary sources and draw conclusions that would then be suitable for inclusion in an article.
This is a featured article and additional sections need to comply with FA criteria, particularly compliance with MOS - in this case, WP:MEDMOS, as well as norms of writing style, such as avoidance of single sentence paragraphs. As a result, I've decided to restore the prior version before the animal studies were added. Here is the text and sources that I've removed:
== Research ==
A study in rats concluded that ketosis delays central nervous system oxygen toxicity. [1]
Some antiepileptic drugs are also hypothesised to delay onset of oxygen-induced seizures in mice. [2]
A study in mice found that biologically produced nitric oxide is part of the mechanism that causes oxygen toxicity, and that superoxide ions inhibit the oxygen-toxicity-causing role of nitric oxide. [3]
References
- ^ D'Agostino, Dominic P; Pilla, Raffaele; Held, Heather E; Landon, Carol S; Puchowicz, Michelle; Brunengraber, Henri; Ari, Csilla; Arnold, Patrick; Dean, Jay B (3 April 2013). "Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats". AJP: Regulatory, Integrative and Comparative Physiology. 304 (10): R829–R836. doi: 10.1152/ajpregu.00506.2012.
- ^ Demchenko, IT; Zhilyaev, SY; Moskvin, AN; Krivchenko, AI; Piantadosi, CA; Allen, BW (15 February 2017). "Antiepileptic drugs prevent seizures in hyperbaric oxygen: A novel model of epileptiform activity". Brain research. 1657: 347–354. PMID 28057450.
- ^ https://www.ncbi.nlm.nih.gov/pubmed/1329105 Extracellular superoxide dismutase, nitric oxide, and central nervous system O2 toxicity. by Oury TD1, Ho YS, Piantadosi CA, Crapo JD., Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9715-9.
If Anthony wishes to reinstate the text, then that should be discussed here first. I'll ask Doc James if he thinks any part of the text or sources might be usable. -- RexxS ( talk) 11:29, 11 April 2017 (UTC)
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Cheers.— InternetArchiveBot ( Report bug) 13:10, 21 September 2017 (UTC)
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I have just modified 3 external links on Oxygen toxicity. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
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Cheers.— InternetArchiveBot ( Report bug) 11:49, 29 September 2017 (UTC)
I made the positive decision to use a minimum column width of 30em as I feel that is the best compromise between whitespace and line-wrapping for this article. That's not to say that I intended the column widths to be set to the default value for {{ Reflist}}, which is subject to change of course. If there is an rationale to use a different minimum column width, then I'm happy to discus it here. -- RexxS ( talk) 11:54, 25 March 2018 (UTC)
There are a few items I have identified as incomplete or requiring some clarification. This is normal, and does not mean the article needs to be delisted as a featured article as they are minor matters, but it is necessary to do some research to find suitable sources before making the changes. · · · Peter Southwood (talk): 06:01, 23 December 2022 (UTC)
Diving Medicine, Hyperbaric Medicine and Neonatal Medicine all have to deal with oxygen toxicity even more than Emergency Medicine. 2605:59C8:11CF:DF10:BCCB:C9FF:FE2A:B121 ( talk) 04:38, 14 June 2023 (UTC)
The article is below FA standard with regard to citations. I have tagged some places where they are needed. Could this be addressed to avoid WP:FAR? Graham Beards ( talk) 12:52, 16 November 2023 (UTC)