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From the article at steroid, it seems technically oleandrin isn't a steroid. I guess it could be classified as a sterol ester. We should probably link to an appropriate ster* article. RandomP ( talk) 14:47, 15 October 2009 (UTC)
Do we have data on topical applications of Oleandrin [derived from oleander (Nerium oleander L.), the evergreen shrub] or Nerium? Consider the current media blitz by the product called Nerium AD, which seems to require a topical application rather than internal consumption. MaynardClark ( talk) 21:45, 9 July 2014 (UTC)
Although this subject isn't my bread and butter, a good amount of it seems to be related to its effect on humans. Feels like we should split a chunk of it off to "Human effects of Oleandrin" or something of the like. Just a thought Drewmutt (^ᴥ^) talk
Hi everybody! Just a note to let you know that I'm not pranking Wikipedia; Axios (a very reliable news source) really does say that Trump is promoting oleandrin as a treatment for COVID 19, with support from Dr. Ben Carson and also from the My-Pillow guy Mike Lindell. They're also promoting it as a dietary supplement. The Axios post on this is only a few hours old so I hope I'm not violating WP: NOTNEWS. BusinessInsider has reported this too. HandsomeMrToad ( talk) 03:50, 17 August 2020 (UTC)
UPDATE: Can everybody please stop adding emotionally-loaded language to the section on COVID19? I agree that Oleandrin is unproven as a treatment for COVID, and this looks like another one of Trump's hype-and-sell tricks, and of course we all feel very strongly about this sort of thing, but we don't know whether or not it will work, and we should try to respect NPOV and keep an encyclopedic tone, and anyway the irony is stronger if you just state the facts and let the reader bring the emotions to the situation. (This is what makes Primo Levi such a great Holocaust-memoirist: he avoids histrionics and writes like a scientist, which is what he was.) Thank you. HandsomeMrToad ( talk) 04:03, 17 August 2020 (UTC)
https://www.newsweek.com/trump-denies-pressing-fda-approve-oleandrin-1525821 Apparently is being pushed by the White House as of AUgust 2020 2601:640:C600:3C20:2DB5:3277:6BD4:B35A ( talk) 18:28, 19 August 2020 (UTC)
→Fair, but phrasing it as "being considered" by unnamed entities suggests the degree of consideration is substantial and done by presumably legitimate groups. Would an encyclopedia say that the theory that the earth is flat is being considered? I don't know what the right language would be, but I don't believe that's it. — Preceding unsigned comment added by 216.180.92.171 ( talk) 04:48, 17 August 2020 (UTC)
Chemical structure - the 6-methyl is missing (ring at lower left)
Structure - has a substitute of an acetyloxy - change "substitute" to "substitution" or just delete "a substitute of"
just like its derivate - change "derivate" to "derivative"
Synthesis - Oleandrin and its derivate - change "derivate" to "derivative"
The oleandrin itself can be won out of - change "won out of" to "isolated from"
Related substances - "apart from its pure form" does not make sense here; delete
Change "structural" to "structurally"
Mechanism of action - Na+ and K+ between the intercellular and extracellular spaces - intercellular is the same as extracellular; presumably it should be intracellular
the Na+ cannot be transported back into the extracellular membrane - change "membrane" to "medium" (the membrane is what separates intracellular from extracellular)
Symptoms - Symptoms of oleandrin poisoning can cause - the symptoms don't cause the effects, the symptoms are the effects; change "cause" to "include"
Treatment - consultation with a cardiologist is recommended when managing significant N. Oleander induced - oleander should not be capitalized & should be followed by - instead of a space
Effects on animals - Cases of sheep lethality have been reported to only one leaf - change "to" to "from"
References - 3. - transformation and fungal elecitation - change "elecitation" to "elicitation". 71.163.180.156 ( talk) 07:57, 16 September 2020 (UTC)
Phase I and Phase II clinical studies are by definition clinical evidence of safety. Even preliminary evidence is still evidence. Therefore the statement that there is no such evidence is false. My edit (with references) to correct this error was undone.
My proposed revision is as follows: Oleandrin is not yet fully approved by regulatory agencies in the United States as a prescription drug or dietary supplement. It has been approved by the FDA for clinical testing in humans. Phase I and Phase II clinical trials showed that oleandrin can be safely administered orally (PBI-05204), and Phase I data showed that it can be safely administered by intramuscular (IM) injection (Anvirzel)[2][3] Dr. Duckman ( talk) 21:21, 6 March 2022 (UTC) Dr. Duckman ( talk) 21:16, 6 March 2022 (UTC)
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||||||||||||||||||||||||||
|
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Oleandrin.
|
![]() |
Daily pageviews of this article
A graph should have been displayed here but
graphs are temporarily disabled. Until they are enabled again, visit the interactive graph at
pageviews.wmcloud.org |
From the article at steroid, it seems technically oleandrin isn't a steroid. I guess it could be classified as a sterol ester. We should probably link to an appropriate ster* article. RandomP ( talk) 14:47, 15 October 2009 (UTC)
Do we have data on topical applications of Oleandrin [derived from oleander (Nerium oleander L.), the evergreen shrub] or Nerium? Consider the current media blitz by the product called Nerium AD, which seems to require a topical application rather than internal consumption. MaynardClark ( talk) 21:45, 9 July 2014 (UTC)
Although this subject isn't my bread and butter, a good amount of it seems to be related to its effect on humans. Feels like we should split a chunk of it off to "Human effects of Oleandrin" or something of the like. Just a thought Drewmutt (^ᴥ^) talk
Hi everybody! Just a note to let you know that I'm not pranking Wikipedia; Axios (a very reliable news source) really does say that Trump is promoting oleandrin as a treatment for COVID 19, with support from Dr. Ben Carson and also from the My-Pillow guy Mike Lindell. They're also promoting it as a dietary supplement. The Axios post on this is only a few hours old so I hope I'm not violating WP: NOTNEWS. BusinessInsider has reported this too. HandsomeMrToad ( talk) 03:50, 17 August 2020 (UTC)
UPDATE: Can everybody please stop adding emotionally-loaded language to the section on COVID19? I agree that Oleandrin is unproven as a treatment for COVID, and this looks like another one of Trump's hype-and-sell tricks, and of course we all feel very strongly about this sort of thing, but we don't know whether or not it will work, and we should try to respect NPOV and keep an encyclopedic tone, and anyway the irony is stronger if you just state the facts and let the reader bring the emotions to the situation. (This is what makes Primo Levi such a great Holocaust-memoirist: he avoids histrionics and writes like a scientist, which is what he was.) Thank you. HandsomeMrToad ( talk) 04:03, 17 August 2020 (UTC)
https://www.newsweek.com/trump-denies-pressing-fda-approve-oleandrin-1525821 Apparently is being pushed by the White House as of AUgust 2020 2601:640:C600:3C20:2DB5:3277:6BD4:B35A ( talk) 18:28, 19 August 2020 (UTC)
→Fair, but phrasing it as "being considered" by unnamed entities suggests the degree of consideration is substantial and done by presumably legitimate groups. Would an encyclopedia say that the theory that the earth is flat is being considered? I don't know what the right language would be, but I don't believe that's it. — Preceding unsigned comment added by 216.180.92.171 ( talk) 04:48, 17 August 2020 (UTC)
Chemical structure - the 6-methyl is missing (ring at lower left)
Structure - has a substitute of an acetyloxy - change "substitute" to "substitution" or just delete "a substitute of"
just like its derivate - change "derivate" to "derivative"
Synthesis - Oleandrin and its derivate - change "derivate" to "derivative"
The oleandrin itself can be won out of - change "won out of" to "isolated from"
Related substances - "apart from its pure form" does not make sense here; delete
Change "structural" to "structurally"
Mechanism of action - Na+ and K+ between the intercellular and extracellular spaces - intercellular is the same as extracellular; presumably it should be intracellular
the Na+ cannot be transported back into the extracellular membrane - change "membrane" to "medium" (the membrane is what separates intracellular from extracellular)
Symptoms - Symptoms of oleandrin poisoning can cause - the symptoms don't cause the effects, the symptoms are the effects; change "cause" to "include"
Treatment - consultation with a cardiologist is recommended when managing significant N. Oleander induced - oleander should not be capitalized & should be followed by - instead of a space
Effects on animals - Cases of sheep lethality have been reported to only one leaf - change "to" to "from"
References - 3. - transformation and fungal elecitation - change "elecitation" to "elicitation". 71.163.180.156 ( talk) 07:57, 16 September 2020 (UTC)
Phase I and Phase II clinical studies are by definition clinical evidence of safety. Even preliminary evidence is still evidence. Therefore the statement that there is no such evidence is false. My edit (with references) to correct this error was undone.
My proposed revision is as follows: Oleandrin is not yet fully approved by regulatory agencies in the United States as a prescription drug or dietary supplement. It has been approved by the FDA for clinical testing in humans. Phase I and Phase II clinical trials showed that oleandrin can be safely administered orally (PBI-05204), and Phase I data showed that it can be safely administered by intramuscular (IM) injection (Anvirzel)[2][3] Dr. Duckman ( talk) 21:21, 6 March 2022 (UTC) Dr. Duckman ( talk) 21:16, 6 March 2022 (UTC)