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The article states:
"Naproxen should not be taken with antidepressants... Naproxen is not contraindicated in the presence of SSRIs, though concomitant use of the medications should be done with caution".
"not contraindicated seems to contradict the other two statements. I'm not a medical professional, but all the definitions of "contraindicated" I dug up, including from the U.S. National Library of Medicine, include either the meaning "use with caution" or "should not use". So, either the article wording needs to be corrected (perhaps distinguishing between relative and absolute contraindication), or the text should reflect disagreement between two sources. — Preceding unsigned comment added by Atkinson 291 ( talk • contribs) 21:47, 15 February 2018 (UTC)
NSAIDs have some warning about alcohol, and I remember this being mentioned to me in person. Should we include something about alcohol and naproxen in the article? - User:Ick) 06:36, 3 September 2007 (UTC)
I'm not a health professional, but I don't believe there is a direct link between the pharmacology of Naproxen (and other NSAIDs) and ethanol. The advice to avoid alcohol is because both NSAIDs and ethanol can cause stomach irritation and gastric bleeding, so ethanol may increase the prevalence and severity of these side effects. —Preceding unsigned comment added by 80.176.142.11 ( talk) 19:44, 6 February 2008 (UTC)
Kenfo 0 ( talk) 22:12, 26 April 2011 (UTC)
There are no known hazardous interactions between Naproxen & Alcohol. NHS Website Alphaceo ( talk) 17:00, 23 May 2013 (UTC)
Definitely a DDI worth mentioning! Thanks for the reminder. Cited a review on PubMed. Biochemistry&Love ( talk) 02:32, 4 May 2017 (UTC)
I added the trade name 'Naprogesic'. Naprogesic is a Naproxen Sodium variant sold in Australia. Not 100% sure if the trade name should be on that list, ob I don't have access to the others to rtfm. Thoughts? 220.240.227.91 09:11, 6 February 2006 (UTC)
This article has an unsourced statement claiming that has been linked to stomach cancer. However, Cancer.org claims it -reduces- the incidence of stomach cancer. http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Can_stomach_cancer_be_prevented_40.asp SailorAlea 12:06, Sep 13 2006
problem solved. -- 84.172.231.31 19:28, 4 March 2007 (UTC)
Naproxen tablet
CPO792 20:01, 15 May 2007 (UTC)CPO792
i think it's known that naproxen sodium can cause stevens-johnson syndrome. http://en.wikipedia.org/wiki/Stevens-Johnson_syndrome —Preceding unsigned comment added by 195.112.144.194 ( talk) 08:18, 22 November 2007 (UTC)
I´m taking naproxen for a operation i have about 10 days ago, i need it to cope wiht the pain and inflamation, but i don´t know when it is nessecity or is startin to become something else, my uestion is, does Naproxen can cause adiction, or who addictive is this drug? 19:22, 25 January 2008. —Preceding unsigned comment added by 201.140.75.250 ( talk)
Naproxen isn't physically addictive, none of the NSAIDs are. You should watch out for any analgesic with an opiate content (codeine, dihydrocodeine, oxycodone, methadone, morphine etc) as these certainly can result in addiction. -- 80.176.142.11 ( talk) 19:54, 6 February 2008 (UTC)
I'm bothered by the following sentence:
The National Institutes of Health prematurely terminated a randomized clinical trial of naproxen and celecoxib for prevention of Alzheimer's disease, after preliminary data suggested an increased risk of major cardiovascular events, such as heart attack or stroke, in patients taking naproxen.
My understanding was that it was known if these cardiovascular events were "major" or quite minor, as the data were never released. That's what I just read here at the Washington Post: < http://www.washingtonpost.com/wp-dyn/articles/A52625-2005Jan31.html> Unless, more information has come up, I would delete the word "major." Eperotao ( talk) 17:24, 23 May 2008 (UTC)
I was told by the pharmacist to always eat with my Naproxen (which I take to cure a pericarditis). A work colleague told me she completely forgot her neck pain due to stomach cramps for taking Naproxen without food. I see no mention of this in the article. Maybe it should be updated? But I can't really mention personal experience as a source for the article... CielProfond ( talk) 16:45, 9 December 2008 (UTC)
Naproxen is an oblong White Pill with the medical imprint code "IP110" following parallel score on the back which is for the patient using the drug can half it.
I think that description should be removed (or ammended), because not all Naproxen tablets look like that, the ones I get are blue, don't have "IP110" nor a score on it. Kyprosサマ ( talk) 05:47, 18 January 2009 (UTC)
I removed the sentence, "Naproxen was designed...while...trying to discover a cure for the common cold" because it wasn't supported by the source cited. However, if the part of the statement excerpted above is actually true, then it should be re-added with proper sourcing. Bwrs ( talk) 16:21, 21 February 2009 (UTC)
While this press release says Aleve isn't available over-the-counter in Quebec, I can assure you that it is available "behind the counter," having bought it here in Montreal several times since mid-July. There is evidently some confusion about the exact meaning of "over-the-counter" here. The article on OTC drugs discusses "restricted OTC substances", which are drugs available without a prescription but stored behind the pharmacy counter and dispensed by the pharmacist. I would say these are still considered OTC drugs, even if they're not on the general pharmacy shelves. "Over-the-counter" is a confusing term anyway.
Further complicating things is the Aleve website, which reads "Sorry, ALEVE® is not available in BC/NFLD at this time. Coupon not valid in Quebec." Does this mean Aleve isn't available at all in B.C. and Newfoundland-Labrador? Or is it available behind the pharmacy counter? I'll be sending an email to the Bayer representative listed in the press release to ask for clarification. Puck35 ( talk) 19:06, 16 August 2009 (UTC)
I deleted this section because its bullshit and someone put it back in. Go read the study in source 5. Theres no statistical significance. —Preceding unsigned comment added by 98.209.40.98 ( talk) 17:20, 19 November 2009 (UTC)
New data 2014 = "NAPROXEN LINKED TO HEART ATTACK RISK FOR OLDER WOMEN. Futurity (7/15) reports that a new study found that regular use of the painkiller naproxen may increase the risk of stroke, heart attack, and even death in postmenopausal women. The researchers analyzed data from more than 160,000 postmenopausal women who were surveyed as part of the Women’s Health Initiative—a 15-year research study funded by the National Institutes of Health." http://www.futurity.org/naproxen-heart-attack-women-731052/ — Preceding unsigned comment added by 128.231.237.7 ( talk) 18:21, 15 July 2014 (UTC)
The article currently concludes with "The National Institutes of Health prematurely terminated a randomized clinical trial[5] of naproxen and celecoxib for prevention of Alzheimer's disease, after preliminary data suggested similar effects to Vioxx, such as heart attack or stroke, in patients taking naproxen." However, the cited source actually states "For celecoxib, ADAPT data do not show the same level of risk as those of the APC trial. The data for naproxen, although not definitive, are suggestive of increased cardiovascular and cerebrovascular risk." [emphasis added]. It seems that the WP article is over stating the case for naproxen--at least the wp claim doesn't seem to follow from the cited source. Ann arbor street ( talk) 20:33, 9 January 2010 (UTC)
I am currently taking brand name Vimovo, 500mg/20mg combination of naproxen and esomeprazole. It was prescribed to me for shoulder tendinitis. I thought I might find more information about it here on Wikipedia, but it seems to be new to you. The NSAID-PPI combination drug is apparently supposed to reduce the chance of NSAID-related ulcers. It appears that Axorid is a similar brand, with different ingredients. I'd edit this article or the other, but this type of combination drug seems to warrant its own page. I'll leave it to others to decide what, if anything, to do with this. 24.57.210.141 ( talk) 02:08, 30 June 2012 (UTC)
Why is it called Naproxen Sodium? The chemical formula states that there isn't actually any sodium in it. 2601:8:8900:436:8006:E424:8DA8:635D ( talk) 19:30, 23 February 2014 (UTC)
I can't find this pill in Drugs.com and Lexi-Comp. Does anyone have proof that this is naproxen? Doc James, maybe you have something? ― Biochemistry🙴❤ 21:27, 17 May 2017 (UTC)
Teva Naproxen EC 500 ( Enteric coating), EC are easier for stomac.
This article does not explain the difference between Naproxen and Naproxen Sodium. In "Sodium Chloride," Sodium and Chlorine are elements. Sodium is metal and with chlorine the sodium chloride salt is produced. But the name "Naproxen Sodium," is not an analogous name. I have run across on several site the statement that "220 mg of Naproxen sodium 'has' 200 mg of Naproxen." I would like this article to explain what that means. Also I would like to know why this drug is sold in 220 mg pills, exclusively over the counter I think; yet it may be prescribed in 500 mg pills. 220 mg does not match with recommended dosages (neither does 440 or 660 mg.)( PeacePeace ( talk) 00:39, 7 September 2019 (UTC))
"where it is only available over the counter for period pain [1]"
User:Artemgy I do not see how the source supports this? Doc James ( talk · contribs · email) 02:02, 12 March 2020 (UTC)
EOx redirects to this page but is not referenced in the article at all. EOx is also used for electrochemical oxidation. The current redirect should be removed since it is not exclusive or expected IMO. Whether it should point to electrochemical oxidation is open to debate but it seems stronger to me than Naproxen. — Preceding unsigned comment added by 2601:19B:200:D340:94E3:6F16:1AE9:484F ( talk) 02:16, 12 April 2023 (UTC)
References
This is the
talk page for discussing improvements to the
Naproxen article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
![]() | This ![]() It is of interest to the following WikiProjects: | ||||||||||||||||||||
|
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Naproxen.
|
![]() |
Daily pageviews of this article
A graph should have been displayed here but
graphs are temporarily disabled. Until they are enabled again, visit the interactive graph at
pageviews.wmcloud.org |
The article states:
"Naproxen should not be taken with antidepressants... Naproxen is not contraindicated in the presence of SSRIs, though concomitant use of the medications should be done with caution".
"not contraindicated seems to contradict the other two statements. I'm not a medical professional, but all the definitions of "contraindicated" I dug up, including from the U.S. National Library of Medicine, include either the meaning "use with caution" or "should not use". So, either the article wording needs to be corrected (perhaps distinguishing between relative and absolute contraindication), or the text should reflect disagreement between two sources. — Preceding unsigned comment added by Atkinson 291 ( talk • contribs) 21:47, 15 February 2018 (UTC)
NSAIDs have some warning about alcohol, and I remember this being mentioned to me in person. Should we include something about alcohol and naproxen in the article? - User:Ick) 06:36, 3 September 2007 (UTC)
I'm not a health professional, but I don't believe there is a direct link between the pharmacology of Naproxen (and other NSAIDs) and ethanol. The advice to avoid alcohol is because both NSAIDs and ethanol can cause stomach irritation and gastric bleeding, so ethanol may increase the prevalence and severity of these side effects. —Preceding unsigned comment added by 80.176.142.11 ( talk) 19:44, 6 February 2008 (UTC)
Kenfo 0 ( talk) 22:12, 26 April 2011 (UTC)
There are no known hazardous interactions between Naproxen & Alcohol. NHS Website Alphaceo ( talk) 17:00, 23 May 2013 (UTC)
Definitely a DDI worth mentioning! Thanks for the reminder. Cited a review on PubMed. Biochemistry&Love ( talk) 02:32, 4 May 2017 (UTC)
I added the trade name 'Naprogesic'. Naprogesic is a Naproxen Sodium variant sold in Australia. Not 100% sure if the trade name should be on that list, ob I don't have access to the others to rtfm. Thoughts? 220.240.227.91 09:11, 6 February 2006 (UTC)
This article has an unsourced statement claiming that has been linked to stomach cancer. However, Cancer.org claims it -reduces- the incidence of stomach cancer. http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Can_stomach_cancer_be_prevented_40.asp SailorAlea 12:06, Sep 13 2006
problem solved. -- 84.172.231.31 19:28, 4 March 2007 (UTC)
Naproxen tablet
CPO792 20:01, 15 May 2007 (UTC)CPO792
i think it's known that naproxen sodium can cause stevens-johnson syndrome. http://en.wikipedia.org/wiki/Stevens-Johnson_syndrome —Preceding unsigned comment added by 195.112.144.194 ( talk) 08:18, 22 November 2007 (UTC)
I´m taking naproxen for a operation i have about 10 days ago, i need it to cope wiht the pain and inflamation, but i don´t know when it is nessecity or is startin to become something else, my uestion is, does Naproxen can cause adiction, or who addictive is this drug? 19:22, 25 January 2008. —Preceding unsigned comment added by 201.140.75.250 ( talk)
Naproxen isn't physically addictive, none of the NSAIDs are. You should watch out for any analgesic with an opiate content (codeine, dihydrocodeine, oxycodone, methadone, morphine etc) as these certainly can result in addiction. -- 80.176.142.11 ( talk) 19:54, 6 February 2008 (UTC)
I'm bothered by the following sentence:
The National Institutes of Health prematurely terminated a randomized clinical trial of naproxen and celecoxib for prevention of Alzheimer's disease, after preliminary data suggested an increased risk of major cardiovascular events, such as heart attack or stroke, in patients taking naproxen.
My understanding was that it was known if these cardiovascular events were "major" or quite minor, as the data were never released. That's what I just read here at the Washington Post: < http://www.washingtonpost.com/wp-dyn/articles/A52625-2005Jan31.html> Unless, more information has come up, I would delete the word "major." Eperotao ( talk) 17:24, 23 May 2008 (UTC)
I was told by the pharmacist to always eat with my Naproxen (which I take to cure a pericarditis). A work colleague told me she completely forgot her neck pain due to stomach cramps for taking Naproxen without food. I see no mention of this in the article. Maybe it should be updated? But I can't really mention personal experience as a source for the article... CielProfond ( talk) 16:45, 9 December 2008 (UTC)
Naproxen is an oblong White Pill with the medical imprint code "IP110" following parallel score on the back which is for the patient using the drug can half it.
I think that description should be removed (or ammended), because not all Naproxen tablets look like that, the ones I get are blue, don't have "IP110" nor a score on it. Kyprosサマ ( talk) 05:47, 18 January 2009 (UTC)
I removed the sentence, "Naproxen was designed...while...trying to discover a cure for the common cold" because it wasn't supported by the source cited. However, if the part of the statement excerpted above is actually true, then it should be re-added with proper sourcing. Bwrs ( talk) 16:21, 21 February 2009 (UTC)
While this press release says Aleve isn't available over-the-counter in Quebec, I can assure you that it is available "behind the counter," having bought it here in Montreal several times since mid-July. There is evidently some confusion about the exact meaning of "over-the-counter" here. The article on OTC drugs discusses "restricted OTC substances", which are drugs available without a prescription but stored behind the pharmacy counter and dispensed by the pharmacist. I would say these are still considered OTC drugs, even if they're not on the general pharmacy shelves. "Over-the-counter" is a confusing term anyway.
Further complicating things is the Aleve website, which reads "Sorry, ALEVE® is not available in BC/NFLD at this time. Coupon not valid in Quebec." Does this mean Aleve isn't available at all in B.C. and Newfoundland-Labrador? Or is it available behind the pharmacy counter? I'll be sending an email to the Bayer representative listed in the press release to ask for clarification. Puck35 ( talk) 19:06, 16 August 2009 (UTC)
I deleted this section because its bullshit and someone put it back in. Go read the study in source 5. Theres no statistical significance. —Preceding unsigned comment added by 98.209.40.98 ( talk) 17:20, 19 November 2009 (UTC)
New data 2014 = "NAPROXEN LINKED TO HEART ATTACK RISK FOR OLDER WOMEN. Futurity (7/15) reports that a new study found that regular use of the painkiller naproxen may increase the risk of stroke, heart attack, and even death in postmenopausal women. The researchers analyzed data from more than 160,000 postmenopausal women who were surveyed as part of the Women’s Health Initiative—a 15-year research study funded by the National Institutes of Health." http://www.futurity.org/naproxen-heart-attack-women-731052/ — Preceding unsigned comment added by 128.231.237.7 ( talk) 18:21, 15 July 2014 (UTC)
The article currently concludes with "The National Institutes of Health prematurely terminated a randomized clinical trial[5] of naproxen and celecoxib for prevention of Alzheimer's disease, after preliminary data suggested similar effects to Vioxx, such as heart attack or stroke, in patients taking naproxen." However, the cited source actually states "For celecoxib, ADAPT data do not show the same level of risk as those of the APC trial. The data for naproxen, although not definitive, are suggestive of increased cardiovascular and cerebrovascular risk." [emphasis added]. It seems that the WP article is over stating the case for naproxen--at least the wp claim doesn't seem to follow from the cited source. Ann arbor street ( talk) 20:33, 9 January 2010 (UTC)
I am currently taking brand name Vimovo, 500mg/20mg combination of naproxen and esomeprazole. It was prescribed to me for shoulder tendinitis. I thought I might find more information about it here on Wikipedia, but it seems to be new to you. The NSAID-PPI combination drug is apparently supposed to reduce the chance of NSAID-related ulcers. It appears that Axorid is a similar brand, with different ingredients. I'd edit this article or the other, but this type of combination drug seems to warrant its own page. I'll leave it to others to decide what, if anything, to do with this. 24.57.210.141 ( talk) 02:08, 30 June 2012 (UTC)
Why is it called Naproxen Sodium? The chemical formula states that there isn't actually any sodium in it. 2601:8:8900:436:8006:E424:8DA8:635D ( talk) 19:30, 23 February 2014 (UTC)
I can't find this pill in Drugs.com and Lexi-Comp. Does anyone have proof that this is naproxen? Doc James, maybe you have something? ― Biochemistry🙴❤ 21:27, 17 May 2017 (UTC)
Teva Naproxen EC 500 ( Enteric coating), EC are easier for stomac.
This article does not explain the difference between Naproxen and Naproxen Sodium. In "Sodium Chloride," Sodium and Chlorine are elements. Sodium is metal and with chlorine the sodium chloride salt is produced. But the name "Naproxen Sodium," is not an analogous name. I have run across on several site the statement that "220 mg of Naproxen sodium 'has' 200 mg of Naproxen." I would like this article to explain what that means. Also I would like to know why this drug is sold in 220 mg pills, exclusively over the counter I think; yet it may be prescribed in 500 mg pills. 220 mg does not match with recommended dosages (neither does 440 or 660 mg.)( PeacePeace ( talk) 00:39, 7 September 2019 (UTC))
"where it is only available over the counter for period pain [1]"
User:Artemgy I do not see how the source supports this? Doc James ( talk · contribs · email) 02:02, 12 March 2020 (UTC)
EOx redirects to this page but is not referenced in the article at all. EOx is also used for electrochemical oxidation. The current redirect should be removed since it is not exclusive or expected IMO. Whether it should point to electrochemical oxidation is open to debate but it seems stronger to me than Naproxen. — Preceding unsigned comment added by 2601:19B:200:D340:94E3:6F16:1AE9:484F ( talk) 02:16, 12 April 2023 (UTC)
References