Motor neuron diseases received a peer review by Wikipedia editors, which is now archived. It may contain ideas you can use to improve this article. |
This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||||||||||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Motor neuron diseases.
|
Daily pageviews of this article
A graph should have been displayed here but
graphs are temporarily disabled. Until they are enabled again, visit the interactive graph at
pageviews.wmcloud.org |
This article was the subject of a Wiki Education Foundation-supported course assignment, between 26 November 2018 and 21 December 2018. Further details are available on the course page. Student editor(s): Rcchang16, Khemphill1, Kokinishimura. Peer reviewers: Mss87, Owens-Campbell, UCSF Roever.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 04:31, 17 January 2022 (UTC)
My father was diagnosed as ALS/MND somewhere June 2004 (the symptoms started around mid of 2003). Currently, he needs respiratory system (with breathing machine) to support his life. For the past 1 and the half year, he was rescued with "resuscitation" at least 2 times. There is no cure so far, we had tried. Those who suffer the same, please accept the fact, tell the patient to accept. Those Scientist who eventually found solutions will be very much appreciated. Millionaire and billionaire, please donate for research generously. For mankind, thank you. LKS 20/1/2007
I just changed the bit saying that Guam is no longer an ALS hotspot- that's untrue. While the Chamorro's don't have the incidence they used to, ALS-PDC on Guam still occurs at higher levels than elswhere.
Enit 03:41, 30 July 2007 (UTC)
In response to both sides of the stem cell debate my own feeling is that Dr. Huang's "treatment" does nothing. This is on the basis of having seen several patients in our clinic who have been there and continued to deteriorate, or in some cases have serious adverse events, as well as a multitude of reports on both Braintalk and www.build-uk.net. Dr. Huang has received a lot of media attention recently in the US and UK so I anticipate that section will be added to over the coming weeks by new posters. It is also worth bearing in mind given the profit to be made from each patient ($20,000), that there is potentially an advertising element to positive spin on stem cell clinics. -- PaulWicks 09:28, 6 October 2005 (UTC)
How often (and whereabouts) are they called first and second motor neurons? Isn't upper and lower MNs much more common. I hate to quote the google test... so i won't. - T 05:56, 11 Apr 2004 (UTC)
To which disease? The first paragraph taught us that MND refers to a whole group of diseases, of which ALS is only one member (even though Americans use the term "ALS" for the whole group). So what exactly is ALS/MND? The whole group or just one member? Also, does "Lou Gehrig's disease" refer to the whole group or just to the specific member? AxelBoldt 15:22, 1 Jul 2004 (UTC)
Is appears that in the US, ALS is used to cover all of the conditions that are elsewhere known as MND and that a number of conditions can be characterrised as MND. What specific variety of MND Lou Gerhig had I have no idea, but I would guess it is likely to be ALS given that ALS is the more common name for the conditions in the US. See http://www.alsmndalliance.org/whatis.html. Mintguy (T) 16:52, 1 Jul 2004 (UTC)
This article should be upgraded with a more natural language. This is a dictionary for everyone not purely a reference for specialists and medical scientists. I have a fealing that many of the strange scientific words could be replaced using dayily language words. If no such word exist one could give a short explanation in the text on most of theese words (preferrably not just in separate articles).
As it stands the article is written in quite scientific terms. Does anyone have any suggestions for how we might write parallel articles in scientific and lay language??? -- PaulWicks 14:46, 1 September 2005 (UTC)
Everywhere in the article, the condition is referred to as "Motor Neurone Disease" (note caps) and yet the title doesn't feature such capitalization. The other one is currently a redirect, but is that the right way around? - Vague | Rant 12:42, Dec 15, 2004 (UTC)
Done. -- PaulWicks 14:45, 1 September 2005 (UTC)
Then subsequently undone, because as pointed out, disease names are onl capitalised if eponymous. First I'd heard of it because that's how I've always written it in the UK including on official documentation. Is decapitalising disease names an american convention? The article is written about MND (rather than ALS) and "neurone" has been spelt in the English way rather than the American "neuron". Any thoughts?
-- PaulWicks 07:40, 2 September 2005 (UTC)
I have an entirely different issue. If you search for "lou gehrig," you get various hits, the link "lou gehrigs disease" redirects you to the Motor Neurone Disease page, while the link "lou gehrig's disease" brings you to the ALS page, which is more accurate. At the least, they should both redirect to the same page. As i'm new to wikipedia, I do not know how to make this correction. Thanks.
Well spotted and good point. Done. -- PaulWicks 21:26, 27 July 2006 (UTC)
> MMA removed as not strictly speaking an MND.
How/Why is MMA "not strictly speaking an MND"?
> Monomelic amyotrophy (MMA) a variant of motor neuron disease
AHands 05:48, 24 May 2005 (UTC)
Because it is not progressive to other regions, does not fall under the criteria of El Escorical Diagnostic criteria for ALS/MND, and is not recognised as such. That it is A disease which affects the Motor Neurones I agree, but that doesn't make it MND. PaulWicks 15:07, September 1st
An
automated Wikipedia link suggester has some possible wiki link suggestions for the
Motor_neurone_disease article, and they have been placed on
this page for your convenience.
Tip: Some people find it helpful if these suggestions are shown on this talk page, rather than on another page. To do this, just add {{User:LinkBot/suggestions/Motor_neurone_disease}} to this page. —
LinkBot 10:32, 17 Dec 2004 (UTC)
I removed the newly added section reflecting this abstract. While it sounds fascinating, I am a bit weary of radical new concepts being introduced on Wikipedia as if they could be the next breakthrough. Only very rarely is this warranted (e.g. when a promising agent makes it to a phase III trial). It may be lightyears before this test is introduced in clinical practice, and it runs the perpetual risk of dying an early death, as have so many other diagnostic tricks of the past. JFW | T@lk 00:44, 25 July 2005 (UTC)
Good call. I've put a little bit on there to warn that MND patients are particularly vulnerable to snake oil salesmen, the results of which I have seen many times. -- PaulWicks 14:49, 1 September 2005 (UTC)
There may be a British/American terminology issue here, but, whatever the cause, the structure of the article is more than a little confused as a result. Why not have separate articles for the individual diseases? -- Sjsilverman 23:14, 26 December 2005 (UTC)
Hi all, I'll try and clear this one up. The terminology is confused everywhere. Therefore the confusion here is reflective of that. I don't think splitting the article would be of any benefit, but I agree there might be more attempts made at consistency. I will have a go and then you can all play with it.
UK: MND = a group of diseases including ALS, PLS, PMA, and PBP. But it also equals ALS, the most common form of the disease. USA: ALS = a group of diseases including ALS, PLS, PMA, and PBP.
Lou Gehrig's Disease = as above
Stephen Hawking says in his introduction to "A Brief History of Time" that he has ALS. If he was being non-specific about his dx, as he is British, he would have said he has MND. Therefore he has ALS, albeit the most slowly progressive occurrence known. There is a seperate article on PLS and I'll start one on PMA. Cheers -- PaulWicks 21:59, 1 February 2006 (UTC)
From http://wiki.iop.kcl.ac.uk/default.aspx/Neurodegeneration/Classification%20of%20Motor%20Neurone%20Diseases.html - Increasingly, it is recognised that there is not a clear distinction between PMA, ALS, PLS, and ALS-FTD. ... a number of authors in the neuropathology literature have suggested that MND is best considered as a multisystem disorder with a number of phenotypes expressing differential involvement of motor and CNS systems -- MND cannot be subdivided into pure and distinct categories as identified by clinical signs and symptoms. Jooler 19:42, 25 February 2006 (UTC)
ROFLMAO, ah the power of google. If you look carefully you'll find I actually wrote that!-- PaulWicks 22:57, 25 February 2006 (UTC)
User:Velho cut and paste moved this page to Motor neuron disease. This was then reverted and "corrected" by a standard move by User:Jfdwolff. Neither of these page moves has been announced or suggested or discussed on the talk page and were made without any consensus. I have just moved the page back to Motor neurone disease. I also note that in the logs of this page is the following "09:36, 20 December 2005 Jfdwolff (Talk | contribs) moved Motor neurone disease to Motor neuron disease over redirect (more common and correct spelling) (revert)". In the US the term ALS is more common and MND tends to be used outside of the US, particularly Britain and Australia. The ALS/MND Alliance], the MND Association, the MND Association of Australia and a host of other organisations use the spelling Neurone. Jooler 10:35, 19 July 2006 (UTC)
I'm very new here and am as close to being without a nationality as can be (having grown up all over), but I thought I'd point out that making this article 'neuron' does seem to make sense. 'Neuron' is accepted in the UK, esp in the academic community, so we'd be choosing a spelling that's accepted in the UK and the US. Moreover, most other articles with 'neuron(e)' in their titles are 'neuron'. /-- Borgipedia 16:25, 19 July 2006 (UTC)
Hm..... If the original page was in American English the title of the new page should have been in American English as well. Seems like a mistake was made. Shouldn't that be corrected? Seems esp so given that 'neuron' is accepted everywhere, but 'neurone' is not. /-- Borgipedia 18:32, 19 July 2006 (UTC)
OK, but shouldn't we use the spelling that's acceptable in both varieties of English, instead of the one acceptable only in one variety? /-- Borgipedia 09:47, 20 July 2006 (UTC)
This might seem like a silly criterion, but "neuron" is a term from ancient greek, and doesn't have an "e" on the end. At least etymologically, "neuron" seems to make more sense. SB Johnny 12:26, 22 July 2006 (UTC)
Makes sense to me. /-- Borgipedia 10:53, 25 July 2006 (UTC)
But it wasn't widely adopted. Most, or at least many, British scientists don't use that spelling, and no American scientists do. So going back to the Greek is probably the best solution, since it involves the most gentle compromise. -- Borgipedia 20:38, 16 August 2006 (UTC)
This article should not be in that category. It is already a member of the parent MND category. JFW | T@lk 21:04, 30 July 2006 (UTC)
I've noticed that MND redirects here wthout question, but is quite often an abbreviation for Minimal (or Minor) Neurological Disorder (or Dysfunction). I haven't time to fix this right now, sorry. Gondooley ( talk) 12:27, 25 June 2008 (UTC)
Dear all, further to a recent deletion of external links I thought I'd go and look up the manual of style guidance on external links on medical articles, which you can read here [3]. In particular please note Large disease-related organisations and government health departments sometimes produce web pages containing substantial information that would be of interest to readers wishing to further study the topic. and If the disease is very rare, then a manageable set of charitable organisations may be of encyclopaedic interest. In these cases, please prefer links that provide information that is likely to be interesting to readers worldwide, such as a detailed article on the specific topic. Thanks, -- PaulWicks ( talk) 13:54, 15 April 2009 (UTC)
I apologise for summarily removing the etymology section of the article. Given that it was, at the time, the etymology of Amyotrophic Lateral Sclerosis, I thought it would be appropriate to move the definition the the specific article dealing with ALS. I see there has been an explanatory paragraph added. Despite this, wouldn't it be more appropriate to reserve the etymological definition of ALS to its corresponding article? In the article in general, in fact, I would say there is a little confusion between MND and ALS (as has already been mentioned on this page). Again,I apologise for removing the content without warning. In the future I will discuss significant changes beforehand. Lynad ( talk) 19:55, 28 April 2009 (UTC)
The following statement was placed in the "Terminology section":
I have left a {{ dubious}} tag on the statement this refers to.- gadfium 05:52, 18 May 2009 (UTC)
Sigh... ALS is a type of MND. But in the US they don't use the term MND, they use ALS as a blanket term for every motor neurone disorder including ALS, but also primary lateral sclerosis and progressive muscular atrophy, for example. People who know more about ALS/MND also use ALS to refer specifically to ALS within the umbrella terms of either ALS or MND. This is why the conference is called the "International Symposium on ALS/MND". I'll find a reference somewhere... It always boggles my mind that the first step in fighting this awful disease has to be wading through a mound of terminology, surely time for the world to agree on what to call it?!-- PaulWicks ( talk) 12:47, 18 May 2009 (UTC)
PMID 19822873 JFW | T@lk 23:04, 1 December 2009 (UTC)
It is requested that an anatomical diagram or diagrams be
included in this article to
improve its quality. Specific illustrations, plots or diagrams can be requested at the
Graphic Lab. For more information, refer to discussion on this page and/or the listing at Wikipedia:Requested images. |
The articles
amyotrophic lateral sclerosis,
motor neurone disease,
primary lateral sclerosis, and
progressive muscular atrophy need a diagram illustrating the upper and lower motor neurone tracts. Ideally I'd like to use this
[4] which is something I use frequently (I adapted it from this
[5] which is what I'd really like to use but I don't know where it originated from. Anyway, if anyone can source the copyright or help me make an original version it'd be very helpful, thanks. --
PaulWicks (
talk)
15:05, 25 April 2009 (UTC)
Created a figure to describe the "Signs and Symptoms">>"Lower and upper motor neuron findings" based on the text: https://commons.wikimedia.org/wiki/File:PEx_UMN_vs_LMN.png Any suggestions are welcome! -- Rcchang16 ( talk) 02:24, 14 December 2018 (UTC)
Sorry for reviving the spelling discussion of 2006 (above) but I currently clean up some articles on neuromuscular disorders and the spelling issue becomes somewhat of importance.
This article uses the spelling neurone. However, as mentioned many times, it is the form neuron that seems to be universally accepted in the scientific community: PubMed has 64,255 results for neuron and only 4,307 results for neurone; ScienceDirect has 34,965 titles for neuron(s) vs. 3,111 for neurone(s). As most if not all other Wikipedia articles use neuron — and as it looks somewhat weird when while describing neurons you have to link to "neurone diseases" — I strongly suggest this article is moved to Motor neuron disease. kashmiri ( talk) 18:41, 21 January 2012 (UTC)
In draft ICD-11, motor neuron disease is a class of disorders that include hereditary motor neuropathies, spinal muscular atrophies, amyotrophic lateral sclerosis, etc. I understand that motor neurone disease in popular British usage refers specifically to amyotrophic lateral sclerosis. However, we have a separate article for ALS and thus motor neuron disease should present only the common parts of the range of disorders.
For example, symptoms of MND in the wider ("correct") sense do not show "at the age of 50-70": in spinal muscular atrophy, another motor neuron disease, symptoms are often apparent at birth or even before. Same about the description of disease progress, prognosis, etc. All these ALS-specific details should me moved to the amyotrophic lateral sclerosis article. Thanks to comment.
kashmiri ( talk) 12:47, 15 May 2012 (UTC)
My question is i am a multiple sclerosis sufferer, can i there for is it possible for me to be affected with mnd?
Thank you
Kenny Lucas — Preceding unsigned comment added by 197.78.35.25 ( talk) 11:05, 27 May 2013 (UTC)
We need a section on treatment in this article. Even if there is no treatment available, then this fact needs to be stated in the article. If there are only treatments that can slow the progression of the disease and/or reduce the severity of symptoms, this needs to also be stated in this much needed section.-- 197.79.9.86 ( talk) 10:44, 21 June 2013 (UTC)
I have read the definition of MND, but how does that deal with the issue of treatment? Of course you need to know what it is in order to treat it, but that in itself is not enough to know what treatment options are available. I am asking for people who are more knowledgable in the field of MND to incorporate the treatment options available into this article if possible.-- 197.79.9.86 ( talk) 15:08, 21 June 2013 (UTC)
Hi, @ Jytdog: I see another issue with this article's lead, so I figured I would bring your comment to the talk page before doing anything else.
You commented "That is a ref about 1 disease. cannot be used to generalize. Please stop editing the lead only - please edit the body."
Which yeah, my edits are tied to experience with neurological "diagnostic odysseys", and specifically with HSP.
But if anything, I thought the previous version was not general enough, and did not reflect MNDs as a group. Instead of cutting a sentence about disability and disease course that was already there, I added to it to make it more broadly representative of all MNDs. (The citation was meant as an example of how the kind of progression implied by the original sentence doesn't describe at least one type of MND.)
It looks like your solution was to cut the original sentence (along with my additions) completely, which seems fine to me. But I also think that one of the most meaningful and accurate generalizations that can be made about MNDs as a group is that the group encompasses an extremely wide range of disability and disease courses. — Preceding unsigned comment added by Legbracesarecool ( talk • contribs) February 2018 (UTC)
I hesitate to make changes on this page, but there appears to be inconsistency re: classification, ex:
"Spinal muscular atrophies (SMA) are sometimes included in the group by some neurologists but it is different disease with clear genetic cause."
"While MND refers to a specific subset of similar diseases, there are numerous other diseases of motor neurons that are referred to collectively as "motor neuron disorders", for instance disease belonging to spinal muscular atrophies.[2] However, they are not classified as "motor neuron diseases" by the tenth International Statistical Classification of Diseases and Related Health Problems (ICD-10), which is the definition followed in this article."
HSP isn't grouped with the MNDs in ICD-10 though, but instead falls under G11. G12 ("Spinal muscular atrophy and related syndromes") contains the MND group (G12.2), and then the MND group contains G12.25, "Progressive spinal muscular atrophy." (Which seems to be another term for PMA, which is listed in the MND definition here, and also on the "Spinal muscular atrophies" page linked from this page...)
Removing HSP from the definitional list might be a fix, along with some clarification re: spinal muscular atrophy references in relation to ICD-10. Legbracesarecool ( talk) 21:22, 2 May 2018 (UTC)
Hi all! We'll be editing this page as a part of a course we're doing in medical school. Our timeline for work is below.
By mid-Week 1 (11/28):
By end of Week 1 (12/1):
By mid-Week 2 (12/5):
By end of Week 2 (12/8):
By mid-Week 3 (12/12):
By end of Week 3 (12/15):
By mid-Week 4 (12/19):
By end of Week 4 (12/21):
Thanks, -- Khemphill1 ( talk) 01:49, 3 December 2018 (UTC)
Hi All, I strongly recommend to use the Talk page or the Draft userspace to work on the article. There are way too many errors that have been introduced by recent editing, while Wikipedia has to contain information as reliable as possible. Please keep in mind that thousands of people consult these articles every single day!
One important point you need to keep in mind is that this is an article on a group of disorders. This comes with a few caveats:
Clearly, someone has confused pathophysiology with etiology. Google both terms! In the meantime, I am deleting the entire Pathophysiology section as wrong. Please feel free to redraft it from scratch, ideally here on the Talk page first, after doublechecking what pathophysiology means.
Also, the correct venue to describe the minute details of the molecular mechanism and systemic effect of ALS is the ALS article. Here, we can of course keep a one-sentence summary, but the appropriate venue for detailed analysis is there.
Given the sheer amount of problems, I decided to go ahead with a cleanup without waiting until the end of assignment. Simply, such unfinished, non-checked text cannot be posted to the Article namespace. Cheers, — kashmīrī TALK 16:48, 15 December 2018 (UTC)
Peer Review: Great job! A few things to consider: *adding sources to the signs/symptoms section *adding some information to the treatment section, perhaps about the general parameters of current treatment, even though you do clearly explain in the section that most diseases don't have treatment *adding a culture and history section, since motor neuron disease is definitely present in pop culture *adding more pictures of physical exam findings if available *adding differential diagnosis to diagnosis section *adding sources to diagnosis section * clarifying what motor neuron disorders are *hyperlinking more frequently, rather than just the first time a term is mentioned. *adding a pathophysiology section Again, great article! Please let me know if you have any questions. Mss87 ( talk) 02:08, 17 December 2018 (UTC)
Peer Review: JR Overall, great job! The article appears to have been improved significantly and certainly flows well. One suggestion I have is to clarify the terminology concerning ALS even earlier in the article if possible. Sometimes I have seen this done in the italicized section even before the lead begins. It is discussed several times throughout the article but it may serve well to redirect those only concerned with ALS even earlier. — Preceding unsigned comment added by UCSF Roever ( talk • contribs) 21:32, 20 December 2018 (UTC)
An editor has identified a potential problem with the redirect Motor neurone disease and has thus listed it for discussion. This discussion will occur at Wikipedia:Redirects for discussion/Log/2022 November 21#Motor neurone disease until a consensus is reached, and readers of this page are welcome to contribute to the discussion. MB 01:47, 21 November 2022 (UTC)
Motor neuron diseases received a peer review by Wikipedia editors, which is now archived. It may contain ideas you can use to improve this article. |
This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||||||||||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Motor neuron diseases.
|
Daily pageviews of this article
A graph should have been displayed here but
graphs are temporarily disabled. Until they are enabled again, visit the interactive graph at
pageviews.wmcloud.org |
This article was the subject of a Wiki Education Foundation-supported course assignment, between 26 November 2018 and 21 December 2018. Further details are available on the course page. Student editor(s): Rcchang16, Khemphill1, Kokinishimura. Peer reviewers: Mss87, Owens-Campbell, UCSF Roever.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 04:31, 17 January 2022 (UTC)
My father was diagnosed as ALS/MND somewhere June 2004 (the symptoms started around mid of 2003). Currently, he needs respiratory system (with breathing machine) to support his life. For the past 1 and the half year, he was rescued with "resuscitation" at least 2 times. There is no cure so far, we had tried. Those who suffer the same, please accept the fact, tell the patient to accept. Those Scientist who eventually found solutions will be very much appreciated. Millionaire and billionaire, please donate for research generously. For mankind, thank you. LKS 20/1/2007
I just changed the bit saying that Guam is no longer an ALS hotspot- that's untrue. While the Chamorro's don't have the incidence they used to, ALS-PDC on Guam still occurs at higher levels than elswhere.
Enit 03:41, 30 July 2007 (UTC)
In response to both sides of the stem cell debate my own feeling is that Dr. Huang's "treatment" does nothing. This is on the basis of having seen several patients in our clinic who have been there and continued to deteriorate, or in some cases have serious adverse events, as well as a multitude of reports on both Braintalk and www.build-uk.net. Dr. Huang has received a lot of media attention recently in the US and UK so I anticipate that section will be added to over the coming weeks by new posters. It is also worth bearing in mind given the profit to be made from each patient ($20,000), that there is potentially an advertising element to positive spin on stem cell clinics. -- PaulWicks 09:28, 6 October 2005 (UTC)
How often (and whereabouts) are they called first and second motor neurons? Isn't upper and lower MNs much more common. I hate to quote the google test... so i won't. - T 05:56, 11 Apr 2004 (UTC)
To which disease? The first paragraph taught us that MND refers to a whole group of diseases, of which ALS is only one member (even though Americans use the term "ALS" for the whole group). So what exactly is ALS/MND? The whole group or just one member? Also, does "Lou Gehrig's disease" refer to the whole group or just to the specific member? AxelBoldt 15:22, 1 Jul 2004 (UTC)
Is appears that in the US, ALS is used to cover all of the conditions that are elsewhere known as MND and that a number of conditions can be characterrised as MND. What specific variety of MND Lou Gerhig had I have no idea, but I would guess it is likely to be ALS given that ALS is the more common name for the conditions in the US. See http://www.alsmndalliance.org/whatis.html. Mintguy (T) 16:52, 1 Jul 2004 (UTC)
This article should be upgraded with a more natural language. This is a dictionary for everyone not purely a reference for specialists and medical scientists. I have a fealing that many of the strange scientific words could be replaced using dayily language words. If no such word exist one could give a short explanation in the text on most of theese words (preferrably not just in separate articles).
As it stands the article is written in quite scientific terms. Does anyone have any suggestions for how we might write parallel articles in scientific and lay language??? -- PaulWicks 14:46, 1 September 2005 (UTC)
Everywhere in the article, the condition is referred to as "Motor Neurone Disease" (note caps) and yet the title doesn't feature such capitalization. The other one is currently a redirect, but is that the right way around? - Vague | Rant 12:42, Dec 15, 2004 (UTC)
Done. -- PaulWicks 14:45, 1 September 2005 (UTC)
Then subsequently undone, because as pointed out, disease names are onl capitalised if eponymous. First I'd heard of it because that's how I've always written it in the UK including on official documentation. Is decapitalising disease names an american convention? The article is written about MND (rather than ALS) and "neurone" has been spelt in the English way rather than the American "neuron". Any thoughts?
-- PaulWicks 07:40, 2 September 2005 (UTC)
I have an entirely different issue. If you search for "lou gehrig," you get various hits, the link "lou gehrigs disease" redirects you to the Motor Neurone Disease page, while the link "lou gehrig's disease" brings you to the ALS page, which is more accurate. At the least, they should both redirect to the same page. As i'm new to wikipedia, I do not know how to make this correction. Thanks.
Well spotted and good point. Done. -- PaulWicks 21:26, 27 July 2006 (UTC)
> MMA removed as not strictly speaking an MND.
How/Why is MMA "not strictly speaking an MND"?
> Monomelic amyotrophy (MMA) a variant of motor neuron disease
AHands 05:48, 24 May 2005 (UTC)
Because it is not progressive to other regions, does not fall under the criteria of El Escorical Diagnostic criteria for ALS/MND, and is not recognised as such. That it is A disease which affects the Motor Neurones I agree, but that doesn't make it MND. PaulWicks 15:07, September 1st
An
automated Wikipedia link suggester has some possible wiki link suggestions for the
Motor_neurone_disease article, and they have been placed on
this page for your convenience.
Tip: Some people find it helpful if these suggestions are shown on this talk page, rather than on another page. To do this, just add {{User:LinkBot/suggestions/Motor_neurone_disease}} to this page. —
LinkBot 10:32, 17 Dec 2004 (UTC)
I removed the newly added section reflecting this abstract. While it sounds fascinating, I am a bit weary of radical new concepts being introduced on Wikipedia as if they could be the next breakthrough. Only very rarely is this warranted (e.g. when a promising agent makes it to a phase III trial). It may be lightyears before this test is introduced in clinical practice, and it runs the perpetual risk of dying an early death, as have so many other diagnostic tricks of the past. JFW | T@lk 00:44, 25 July 2005 (UTC)
Good call. I've put a little bit on there to warn that MND patients are particularly vulnerable to snake oil salesmen, the results of which I have seen many times. -- PaulWicks 14:49, 1 September 2005 (UTC)
There may be a British/American terminology issue here, but, whatever the cause, the structure of the article is more than a little confused as a result. Why not have separate articles for the individual diseases? -- Sjsilverman 23:14, 26 December 2005 (UTC)
Hi all, I'll try and clear this one up. The terminology is confused everywhere. Therefore the confusion here is reflective of that. I don't think splitting the article would be of any benefit, but I agree there might be more attempts made at consistency. I will have a go and then you can all play with it.
UK: MND = a group of diseases including ALS, PLS, PMA, and PBP. But it also equals ALS, the most common form of the disease. USA: ALS = a group of diseases including ALS, PLS, PMA, and PBP.
Lou Gehrig's Disease = as above
Stephen Hawking says in his introduction to "A Brief History of Time" that he has ALS. If he was being non-specific about his dx, as he is British, he would have said he has MND. Therefore he has ALS, albeit the most slowly progressive occurrence known. There is a seperate article on PLS and I'll start one on PMA. Cheers -- PaulWicks 21:59, 1 February 2006 (UTC)
From http://wiki.iop.kcl.ac.uk/default.aspx/Neurodegeneration/Classification%20of%20Motor%20Neurone%20Diseases.html - Increasingly, it is recognised that there is not a clear distinction between PMA, ALS, PLS, and ALS-FTD. ... a number of authors in the neuropathology literature have suggested that MND is best considered as a multisystem disorder with a number of phenotypes expressing differential involvement of motor and CNS systems -- MND cannot be subdivided into pure and distinct categories as identified by clinical signs and symptoms. Jooler 19:42, 25 February 2006 (UTC)
ROFLMAO, ah the power of google. If you look carefully you'll find I actually wrote that!-- PaulWicks 22:57, 25 February 2006 (UTC)
User:Velho cut and paste moved this page to Motor neuron disease. This was then reverted and "corrected" by a standard move by User:Jfdwolff. Neither of these page moves has been announced or suggested or discussed on the talk page and were made without any consensus. I have just moved the page back to Motor neurone disease. I also note that in the logs of this page is the following "09:36, 20 December 2005 Jfdwolff (Talk | contribs) moved Motor neurone disease to Motor neuron disease over redirect (more common and correct spelling) (revert)". In the US the term ALS is more common and MND tends to be used outside of the US, particularly Britain and Australia. The ALS/MND Alliance], the MND Association, the MND Association of Australia and a host of other organisations use the spelling Neurone. Jooler 10:35, 19 July 2006 (UTC)
I'm very new here and am as close to being without a nationality as can be (having grown up all over), but I thought I'd point out that making this article 'neuron' does seem to make sense. 'Neuron' is accepted in the UK, esp in the academic community, so we'd be choosing a spelling that's accepted in the UK and the US. Moreover, most other articles with 'neuron(e)' in their titles are 'neuron'. /-- Borgipedia 16:25, 19 July 2006 (UTC)
Hm..... If the original page was in American English the title of the new page should have been in American English as well. Seems like a mistake was made. Shouldn't that be corrected? Seems esp so given that 'neuron' is accepted everywhere, but 'neurone' is not. /-- Borgipedia 18:32, 19 July 2006 (UTC)
OK, but shouldn't we use the spelling that's acceptable in both varieties of English, instead of the one acceptable only in one variety? /-- Borgipedia 09:47, 20 July 2006 (UTC)
This might seem like a silly criterion, but "neuron" is a term from ancient greek, and doesn't have an "e" on the end. At least etymologically, "neuron" seems to make more sense. SB Johnny 12:26, 22 July 2006 (UTC)
Makes sense to me. /-- Borgipedia 10:53, 25 July 2006 (UTC)
But it wasn't widely adopted. Most, or at least many, British scientists don't use that spelling, and no American scientists do. So going back to the Greek is probably the best solution, since it involves the most gentle compromise. -- Borgipedia 20:38, 16 August 2006 (UTC)
This article should not be in that category. It is already a member of the parent MND category. JFW | T@lk 21:04, 30 July 2006 (UTC)
I've noticed that MND redirects here wthout question, but is quite often an abbreviation for Minimal (or Minor) Neurological Disorder (or Dysfunction). I haven't time to fix this right now, sorry. Gondooley ( talk) 12:27, 25 June 2008 (UTC)
Dear all, further to a recent deletion of external links I thought I'd go and look up the manual of style guidance on external links on medical articles, which you can read here [3]. In particular please note Large disease-related organisations and government health departments sometimes produce web pages containing substantial information that would be of interest to readers wishing to further study the topic. and If the disease is very rare, then a manageable set of charitable organisations may be of encyclopaedic interest. In these cases, please prefer links that provide information that is likely to be interesting to readers worldwide, such as a detailed article on the specific topic. Thanks, -- PaulWicks ( talk) 13:54, 15 April 2009 (UTC)
I apologise for summarily removing the etymology section of the article. Given that it was, at the time, the etymology of Amyotrophic Lateral Sclerosis, I thought it would be appropriate to move the definition the the specific article dealing with ALS. I see there has been an explanatory paragraph added. Despite this, wouldn't it be more appropriate to reserve the etymological definition of ALS to its corresponding article? In the article in general, in fact, I would say there is a little confusion between MND and ALS (as has already been mentioned on this page). Again,I apologise for removing the content without warning. In the future I will discuss significant changes beforehand. Lynad ( talk) 19:55, 28 April 2009 (UTC)
The following statement was placed in the "Terminology section":
I have left a {{ dubious}} tag on the statement this refers to.- gadfium 05:52, 18 May 2009 (UTC)
Sigh... ALS is a type of MND. But in the US they don't use the term MND, they use ALS as a blanket term for every motor neurone disorder including ALS, but also primary lateral sclerosis and progressive muscular atrophy, for example. People who know more about ALS/MND also use ALS to refer specifically to ALS within the umbrella terms of either ALS or MND. This is why the conference is called the "International Symposium on ALS/MND". I'll find a reference somewhere... It always boggles my mind that the first step in fighting this awful disease has to be wading through a mound of terminology, surely time for the world to agree on what to call it?!-- PaulWicks ( talk) 12:47, 18 May 2009 (UTC)
PMID 19822873 JFW | T@lk 23:04, 1 December 2009 (UTC)
It is requested that an anatomical diagram or diagrams be
included in this article to
improve its quality. Specific illustrations, plots or diagrams can be requested at the
Graphic Lab. For more information, refer to discussion on this page and/or the listing at Wikipedia:Requested images. |
The articles
amyotrophic lateral sclerosis,
motor neurone disease,
primary lateral sclerosis, and
progressive muscular atrophy need a diagram illustrating the upper and lower motor neurone tracts. Ideally I'd like to use this
[4] which is something I use frequently (I adapted it from this
[5] which is what I'd really like to use but I don't know where it originated from. Anyway, if anyone can source the copyright or help me make an original version it'd be very helpful, thanks. --
PaulWicks (
talk)
15:05, 25 April 2009 (UTC)
Created a figure to describe the "Signs and Symptoms">>"Lower and upper motor neuron findings" based on the text: https://commons.wikimedia.org/wiki/File:PEx_UMN_vs_LMN.png Any suggestions are welcome! -- Rcchang16 ( talk) 02:24, 14 December 2018 (UTC)
Sorry for reviving the spelling discussion of 2006 (above) but I currently clean up some articles on neuromuscular disorders and the spelling issue becomes somewhat of importance.
This article uses the spelling neurone. However, as mentioned many times, it is the form neuron that seems to be universally accepted in the scientific community: PubMed has 64,255 results for neuron and only 4,307 results for neurone; ScienceDirect has 34,965 titles for neuron(s) vs. 3,111 for neurone(s). As most if not all other Wikipedia articles use neuron — and as it looks somewhat weird when while describing neurons you have to link to "neurone diseases" — I strongly suggest this article is moved to Motor neuron disease. kashmiri ( talk) 18:41, 21 January 2012 (UTC)
In draft ICD-11, motor neuron disease is a class of disorders that include hereditary motor neuropathies, spinal muscular atrophies, amyotrophic lateral sclerosis, etc. I understand that motor neurone disease in popular British usage refers specifically to amyotrophic lateral sclerosis. However, we have a separate article for ALS and thus motor neuron disease should present only the common parts of the range of disorders.
For example, symptoms of MND in the wider ("correct") sense do not show "at the age of 50-70": in spinal muscular atrophy, another motor neuron disease, symptoms are often apparent at birth or even before. Same about the description of disease progress, prognosis, etc. All these ALS-specific details should me moved to the amyotrophic lateral sclerosis article. Thanks to comment.
kashmiri ( talk) 12:47, 15 May 2012 (UTC)
My question is i am a multiple sclerosis sufferer, can i there for is it possible for me to be affected with mnd?
Thank you
Kenny Lucas — Preceding unsigned comment added by 197.78.35.25 ( talk) 11:05, 27 May 2013 (UTC)
We need a section on treatment in this article. Even if there is no treatment available, then this fact needs to be stated in the article. If there are only treatments that can slow the progression of the disease and/or reduce the severity of symptoms, this needs to also be stated in this much needed section.-- 197.79.9.86 ( talk) 10:44, 21 June 2013 (UTC)
I have read the definition of MND, but how does that deal with the issue of treatment? Of course you need to know what it is in order to treat it, but that in itself is not enough to know what treatment options are available. I am asking for people who are more knowledgable in the field of MND to incorporate the treatment options available into this article if possible.-- 197.79.9.86 ( talk) 15:08, 21 June 2013 (UTC)
Hi, @ Jytdog: I see another issue with this article's lead, so I figured I would bring your comment to the talk page before doing anything else.
You commented "That is a ref about 1 disease. cannot be used to generalize. Please stop editing the lead only - please edit the body."
Which yeah, my edits are tied to experience with neurological "diagnostic odysseys", and specifically with HSP.
But if anything, I thought the previous version was not general enough, and did not reflect MNDs as a group. Instead of cutting a sentence about disability and disease course that was already there, I added to it to make it more broadly representative of all MNDs. (The citation was meant as an example of how the kind of progression implied by the original sentence doesn't describe at least one type of MND.)
It looks like your solution was to cut the original sentence (along with my additions) completely, which seems fine to me. But I also think that one of the most meaningful and accurate generalizations that can be made about MNDs as a group is that the group encompasses an extremely wide range of disability and disease courses. — Preceding unsigned comment added by Legbracesarecool ( talk • contribs) February 2018 (UTC)
I hesitate to make changes on this page, but there appears to be inconsistency re: classification, ex:
"Spinal muscular atrophies (SMA) are sometimes included in the group by some neurologists but it is different disease with clear genetic cause."
"While MND refers to a specific subset of similar diseases, there are numerous other diseases of motor neurons that are referred to collectively as "motor neuron disorders", for instance disease belonging to spinal muscular atrophies.[2] However, they are not classified as "motor neuron diseases" by the tenth International Statistical Classification of Diseases and Related Health Problems (ICD-10), which is the definition followed in this article."
HSP isn't grouped with the MNDs in ICD-10 though, but instead falls under G11. G12 ("Spinal muscular atrophy and related syndromes") contains the MND group (G12.2), and then the MND group contains G12.25, "Progressive spinal muscular atrophy." (Which seems to be another term for PMA, which is listed in the MND definition here, and also on the "Spinal muscular atrophies" page linked from this page...)
Removing HSP from the definitional list might be a fix, along with some clarification re: spinal muscular atrophy references in relation to ICD-10. Legbracesarecool ( talk) 21:22, 2 May 2018 (UTC)
Hi all! We'll be editing this page as a part of a course we're doing in medical school. Our timeline for work is below.
By mid-Week 1 (11/28):
By end of Week 1 (12/1):
By mid-Week 2 (12/5):
By end of Week 2 (12/8):
By mid-Week 3 (12/12):
By end of Week 3 (12/15):
By mid-Week 4 (12/19):
By end of Week 4 (12/21):
Thanks, -- Khemphill1 ( talk) 01:49, 3 December 2018 (UTC)
Hi All, I strongly recommend to use the Talk page or the Draft userspace to work on the article. There are way too many errors that have been introduced by recent editing, while Wikipedia has to contain information as reliable as possible. Please keep in mind that thousands of people consult these articles every single day!
One important point you need to keep in mind is that this is an article on a group of disorders. This comes with a few caveats:
Clearly, someone has confused pathophysiology with etiology. Google both terms! In the meantime, I am deleting the entire Pathophysiology section as wrong. Please feel free to redraft it from scratch, ideally here on the Talk page first, after doublechecking what pathophysiology means.
Also, the correct venue to describe the minute details of the molecular mechanism and systemic effect of ALS is the ALS article. Here, we can of course keep a one-sentence summary, but the appropriate venue for detailed analysis is there.
Given the sheer amount of problems, I decided to go ahead with a cleanup without waiting until the end of assignment. Simply, such unfinished, non-checked text cannot be posted to the Article namespace. Cheers, — kashmīrī TALK 16:48, 15 December 2018 (UTC)
Peer Review: Great job! A few things to consider: *adding sources to the signs/symptoms section *adding some information to the treatment section, perhaps about the general parameters of current treatment, even though you do clearly explain in the section that most diseases don't have treatment *adding a culture and history section, since motor neuron disease is definitely present in pop culture *adding more pictures of physical exam findings if available *adding differential diagnosis to diagnosis section *adding sources to diagnosis section * clarifying what motor neuron disorders are *hyperlinking more frequently, rather than just the first time a term is mentioned. *adding a pathophysiology section Again, great article! Please let me know if you have any questions. Mss87 ( talk) 02:08, 17 December 2018 (UTC)
Peer Review: JR Overall, great job! The article appears to have been improved significantly and certainly flows well. One suggestion I have is to clarify the terminology concerning ALS even earlier in the article if possible. Sometimes I have seen this done in the italicized section even before the lead begins. It is discussed several times throughout the article but it may serve well to redirect those only concerned with ALS even earlier. — Preceding unsigned comment added by UCSF Roever ( talk • contribs) 21:32, 20 December 2018 (UTC)
An editor has identified a potential problem with the redirect Motor neurone disease and has thus listed it for discussion. This discussion will occur at Wikipedia:Redirects for discussion/Log/2022 November 21#Motor neurone disease until a consensus is reached, and readers of this page are welcome to contribute to the discussion. MB 01:47, 21 November 2022 (UTC)