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This article was the subject of a Wiki Education Foundation-supported course assignment, between 1 September 2020 and 17 December 2020. Further details are available
on the course page. Student editor(s):
Chocolatecalorimetry.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 04:28, 17 January 2022 (UTC)
The first sentence in the article states that morphogenesis, differentiation and growth are the 3 essential aspects of development. Cell death and cell fate specification are not mentioned. Fate is not synonymous with differentiation. I am surprised to see the Bicoid gradient and A-P Drosophila polarity in this article. It is not an example of morphogenesis at all - this is an example of how different cell fates are specified based on position. All of the sections on the A-P/gradient/segmentation belong in an article on cell fate specification in a syncytium. Part of the confusion probably comes from the similarity of the words Morphogenesis (forming structure) and Morphogen (cell fate specifying molecule). The morphogenesis article should concentrate on cell migration, cell shape changes, structure formation, tube formation, cell aggregation, programmed cell death, tissue dispersion, cell adhesion, extracellular matrix... Dr d12 23:13, 30 September 2007 (UTC) == I cut the entire A-P patterning section and moved it into the "pattern formation" page. Dr d12 17:53, 11 October 2007 (UTC)
"Thes morphogenes (proteins that control morphogenesis) that determine the fate of cells are proteins that interact with DNA."
Can you provide a source that defines the use of the term "morphogene"?
I found this: "morphogenes (previously known as morphogenic genes)" but I'm not sure that "morphogenic genes" has a clear meaning either.
The term suggests "morphogenesis". There are many proteins besides DNA-binding proteins that control morphogenesis.
I assume that "the fate of cells" means their differentiation. Again, I agree that there are DNA binding proteins that "determine the fate of cells" but there are also other proteins that do not bind DNA and play roles in the control of differentiation. The control of morphogenesis by DNA-binding proteins is indirect: there must be other proteins that leave the nucleus and actually make things happen outside the nucleus.
Maybe it should be, "Many of the morphogenes (proteins that control morphogenesis) that determine the fate of cells are proteins that interact with DNA."
The developmental biology page gives a standard description of the parts of developmental biology, "...developmental biology studies the genetic control of cell growth, differentiation and morphogenesis."
It may be confusing for the reader to follow the link to "morphogenesis" and find this: "Morphogenesis.....describes the process of cellular differentiation, distribution and growth....which gives rise to tissues, organs and anatomy."
This is how the Gilbert text describes morphogenesis: "The question of morphogenesis. Our differentiated cells are not randomly distributed. Rather, they are organized into intricate tissues and organs. These organs are arranged in a given way: the fingers are always at the tips of our hands, never in the middle; the eyes are always in our heads, not in our toes or gut. This creation of ordered form is called morphogenesis. How can the cells form such ordered structures?" JWSchmidt 01:21, 17 Mar 2004 (UTC)
There is no such thing as the morphogenesis of a species. What is actually described for Drosophila melanogaster is some of the key features of one basic developmental process, the establishment of the polarized body plan along the anterior-posterior axis.
I suspect that nobody is really concerned with the Morphogenesis page. It needs to be completely re-worked.
Shouldnt this D'Arcy Thompson's contribution to the topic not be mentioned ? Shyamal 10:25, 1 Apr 2004 (UTC)
would sympathtic editors consider a positive vote here? [1] Slrubenstein | Talk 15:34, 23 August 2006 (UTC)
Why is there a link to Projective geometry in the article? Tbc2 12:36, 25 October 2006 (UTC)
Three news reports saying that Alan Turing's theory of morphogenesis has been proven. [2] [3] [4] Anyone able to expand on that ? EdwardLane ( talk) 13:06, 24 February 2012 (UTC)
I think to say it is proven is an exaggeration. The model is useful and helps in rational thought about morphogenesis but Turgins model is insufficient to explain all aspects of morphogenesis. Bjorklund21 ( talk) 00:12, 23 September 2016 (UTC)
After posting this comment, I will correct the citation for D'Arcy Wentworth Thompson's "On Growth and Form". The book cited is the abridged version, printed 2004, and first published 1961, and comprising some 349 pages, with an editor responsible for the abridgement. It is NOT the 1917 version. It is also not the unabridged version published by Dover in 1992, comprising 1116 pages.
The gold standard in referencing is that one cites sufficient information to be able track down the SPECIFIC publication being cited. One most certainly DOES NOT cite a given publication then reference a completely different version. For out of print, or reprinted publications of early books, this can get cumbersome, but this is in fact where the gold standard is most critical, and where dumbing things down is most unhelpful. Wotnow ( talk) 13:40, 11 December 2012 (UTC)
There are several articles which appear to form a cluster but with a) unclear relationships, and b) various states of undress - missing citations, over-technical explanations without decent introduction, and above all c) no proper co-ordination to give readers an overview either of the individual articles or of how to navigate among them.
I came to all this from Patterns in nature which touches on morphogenesis via its results. However the mechanisms are complicated and as yet poorly explained here in Wikipedia. We need a specialist to sort out the articles in this area. Chiswick Chap ( talk) 10:54, 13 December 2012 (UTC)
I removed the sentence about the "alternative hypotheses" of Albert Harris because it made no sense and had no citations. — Preceding unsigned comment added by 66.57.19.49 ( talk) 00:43, 8 April 2013 (UTC)
More about morphogenesis in plants should be included. They provide more simple examples because, unlike animal cells, plant cells are restricted in movement about the organism by cellulose cell walls. Jonhorridge ( talk) 20:55, 21 December 2016 (UTC)
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||
|
This article was the subject of a Wiki Education Foundation-supported course assignment, between 1 September 2020 and 17 December 2020. Further details are available
on the course page. Student editor(s):
Chocolatecalorimetry.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 04:28, 17 January 2022 (UTC)
The first sentence in the article states that morphogenesis, differentiation and growth are the 3 essential aspects of development. Cell death and cell fate specification are not mentioned. Fate is not synonymous with differentiation. I am surprised to see the Bicoid gradient and A-P Drosophila polarity in this article. It is not an example of morphogenesis at all - this is an example of how different cell fates are specified based on position. All of the sections on the A-P/gradient/segmentation belong in an article on cell fate specification in a syncytium. Part of the confusion probably comes from the similarity of the words Morphogenesis (forming structure) and Morphogen (cell fate specifying molecule). The morphogenesis article should concentrate on cell migration, cell shape changes, structure formation, tube formation, cell aggregation, programmed cell death, tissue dispersion, cell adhesion, extracellular matrix... Dr d12 23:13, 30 September 2007 (UTC) == I cut the entire A-P patterning section and moved it into the "pattern formation" page. Dr d12 17:53, 11 October 2007 (UTC)
"Thes morphogenes (proteins that control morphogenesis) that determine the fate of cells are proteins that interact with DNA."
Can you provide a source that defines the use of the term "morphogene"?
I found this: "morphogenes (previously known as morphogenic genes)" but I'm not sure that "morphogenic genes" has a clear meaning either.
The term suggests "morphogenesis". There are many proteins besides DNA-binding proteins that control morphogenesis.
I assume that "the fate of cells" means their differentiation. Again, I agree that there are DNA binding proteins that "determine the fate of cells" but there are also other proteins that do not bind DNA and play roles in the control of differentiation. The control of morphogenesis by DNA-binding proteins is indirect: there must be other proteins that leave the nucleus and actually make things happen outside the nucleus.
Maybe it should be, "Many of the morphogenes (proteins that control morphogenesis) that determine the fate of cells are proteins that interact with DNA."
The developmental biology page gives a standard description of the parts of developmental biology, "...developmental biology studies the genetic control of cell growth, differentiation and morphogenesis."
It may be confusing for the reader to follow the link to "morphogenesis" and find this: "Morphogenesis.....describes the process of cellular differentiation, distribution and growth....which gives rise to tissues, organs and anatomy."
This is how the Gilbert text describes morphogenesis: "The question of morphogenesis. Our differentiated cells are not randomly distributed. Rather, they are organized into intricate tissues and organs. These organs are arranged in a given way: the fingers are always at the tips of our hands, never in the middle; the eyes are always in our heads, not in our toes or gut. This creation of ordered form is called morphogenesis. How can the cells form such ordered structures?" JWSchmidt 01:21, 17 Mar 2004 (UTC)
There is no such thing as the morphogenesis of a species. What is actually described for Drosophila melanogaster is some of the key features of one basic developmental process, the establishment of the polarized body plan along the anterior-posterior axis.
I suspect that nobody is really concerned with the Morphogenesis page. It needs to be completely re-worked.
Shouldnt this D'Arcy Thompson's contribution to the topic not be mentioned ? Shyamal 10:25, 1 Apr 2004 (UTC)
would sympathtic editors consider a positive vote here? [1] Slrubenstein | Talk 15:34, 23 August 2006 (UTC)
Why is there a link to Projective geometry in the article? Tbc2 12:36, 25 October 2006 (UTC)
Three news reports saying that Alan Turing's theory of morphogenesis has been proven. [2] [3] [4] Anyone able to expand on that ? EdwardLane ( talk) 13:06, 24 February 2012 (UTC)
I think to say it is proven is an exaggeration. The model is useful and helps in rational thought about morphogenesis but Turgins model is insufficient to explain all aspects of morphogenesis. Bjorklund21 ( talk) 00:12, 23 September 2016 (UTC)
After posting this comment, I will correct the citation for D'Arcy Wentworth Thompson's "On Growth and Form". The book cited is the abridged version, printed 2004, and first published 1961, and comprising some 349 pages, with an editor responsible for the abridgement. It is NOT the 1917 version. It is also not the unabridged version published by Dover in 1992, comprising 1116 pages.
The gold standard in referencing is that one cites sufficient information to be able track down the SPECIFIC publication being cited. One most certainly DOES NOT cite a given publication then reference a completely different version. For out of print, or reprinted publications of early books, this can get cumbersome, but this is in fact where the gold standard is most critical, and where dumbing things down is most unhelpful. Wotnow ( talk) 13:40, 11 December 2012 (UTC)
There are several articles which appear to form a cluster but with a) unclear relationships, and b) various states of undress - missing citations, over-technical explanations without decent introduction, and above all c) no proper co-ordination to give readers an overview either of the individual articles or of how to navigate among them.
I came to all this from Patterns in nature which touches on morphogenesis via its results. However the mechanisms are complicated and as yet poorly explained here in Wikipedia. We need a specialist to sort out the articles in this area. Chiswick Chap ( talk) 10:54, 13 December 2012 (UTC)
I removed the sentence about the "alternative hypotheses" of Albert Harris because it made no sense and had no citations. — Preceding unsigned comment added by 66.57.19.49 ( talk) 00:43, 8 April 2013 (UTC)
More about morphogenesis in plants should be included. They provide more simple examples because, unlike animal cells, plant cells are restricted in movement about the organism by cellulose cell walls. Jonhorridge ( talk) 20:55, 21 December 2016 (UTC)