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I tagged for cleanup because an information box was showing up on top of the article text. I don't have the personal knowhow to clean that up. Justin Z 18:16, 2 April 2007 (UTC)
I object to the term 'methadone addict'. I'm sure some users of street-methadone potentiate with meclizine, but I believe that some of those in methadone maintenance programs do as well. I don't think those in methadone maintenance should be called 'methadone addicts', regardless of the fact that they are physically addicted to methadone. I'm changing the term to 'methadone users'. 24.196.111.104 ( talk) 00:21, 3 June 2009 (UTC
The following text was lost, apparently due to a copypaste page move on 8 November 2010.
-- ἀνυπόδητος ( talk) 19:16, 17 December 2010 (UTC)
I know that this was added well over 2 years ago, but I appreciate that you've added this information here. I just don't understand why it's not on the main Meclozine Wiki page, though. I was looking all over the place trying to find some type of mechanism of action/usage/etc. comparison between meclizine and the other drugs in this family, particularly hydroxyzine, beyond the label uses of nausea and dizziness caused by motion sickness, such as comparison of meclizine to the others (again, particularly hydroxyzine) in effectiveness as an antihistamine and specific antihistamine action (which I'm surprised I couldn't find anything about besides here, considering that they're all in the same family, which is first-generation *antihistamines*), any anti-pruritic actions, possible anti-anxiety actions comparable to hydroxyzine, any possible comparable potentiating actions co-administered with opioid analgesics with hydroxyzine and promethazine (no, it's not for recreational use. I take 24/7 pain meds for chronic pain and I have a high tolerance to my pain medications, even when I take my breakthrough pain med, but I'm still rather young, and have a list of numerous surgeries I'm expecting over the course of the net few years, so I'm looking for ways to potentiate my pain meds, so I can either take less of a dose of my BT med, and/or lessen the frequency and perhaps just take a potentiating drug for the milder BT pain taken only with my long-acting medication that's taken on a schedule and always in my system at the same level, as I'm wondering if I were to take a drug that potentiates analgesia from opiates [one that actually *does* increase analgesia from opiates, at least for me] by itself, and just with my long-acting pain medication, if the potentiating/adjuvant drug would work enough just with my long-acting medication taking it "alone", rather than with the BT pain medication, that it would work taken "alone" as an analgesic for the least severe breakthrough pain that I would take an extra pain medication for. I figure anything in this drug family, or just anything that supposedly potentiates opiate analgesia, would all be at least one step up from Tylenol in effectiveness, since that doesn't work for me at all.). This is the only place I could find any kind of information like that, though. I'd totally forgotten about the "talk" page on Wikipedia topic pages until just now, too, so I spent much more time searching around for something I could have just read here in the first 5 minutes of my search, because this was the first search result I clicked on. The information you've added here really needs to be added onto the main Meclozine page, too, because when I did a Google search for Meclizine (how it's spelled on the boxes I just got from the store), the Wikipedia result automatically goes to this result, spelled Meclozine, so anyone who does an internet search for meclizine using either spelling will automatically be led to this page so even if this information might be elsewhere on here, I would assume the majority of people would never see the additional information that's stated here, maybe also on some other page elsewhere, because the majority of people using Wikipedia don't click on the "talk" link on the top of the page, or even see it there or know it's there in the first place. Just look at me-I'm signed up here, I know the talk pages are there, I've browsed the "talk" sections plenty of times before, but I went quite a long time before making my way here and seeing this cut-off info, that happens to contain exactly the information I spent a long time looking for, because it totally slipped my mind to look here. Someone needs to edit this page and copy all the drug effects listed here onto the main page. And considering that it was added over 2 years ago, it's been too long of a wait already. Hopefully someone with much more authority than myself to edit pages here will soon read this and finally edit in this additional information. --
Poisonalice (
talk) 10:34, 17 February 2013 (UTC)
Thanks, it's much appreciated, and I'm sure that there will be other people who will come along and appreciate the information added back as well. I'm sure that there will also be someone that will come along and provide the needed citations, as well. Thanks for the well wishes. It does help to a certain degree. I have degenerative disc disease, numerous herniated and degenerating discs up and down my spine, sciatica from breaking my tailbone so many times, fibromyalgia, carpal tunnel in both hands, tendinitis, shoulder separation, and arthritis in my left shoulder (I need surgery on it), and bone spurs on my right knee from an old injury and surgery, which I also need (another) surgery on to scrape the bones spurs off my kneecap. There may be one or two things missing from that list LOL! SO yeah, I'm on some pretty heavy duty pain medications, but I have high tolerances to all medications, and I develop tolerances very fast, too, probably because I'm a fast metabolizer of drugs. Thanks for asking :) I'm sure I gave you more information than you expected though HAHA! Poisonalice ( talk) 03:06, 8 March 2013 (UTC)
The drug is "Meclizine," not "Meclozine." At least in English-speaking countries...for which this article is intended. — Preceding unsigned comment added by 67.79.29.210 ( talk) 18:45, 18 October 2012 (UTC)
My apologies. You are obviously correct. — Preceding unsigned comment added by 50.84.64.2 ( talk) 17:48, 25 October 2012 (UTC)
The previous user was correct; it is indeed Meclizine per WHO INN's. See http://whqlibdoc.who.int/hq/1997/WHO_PHARM_S_NOM_1570.pdf -izine: diphenylmethyl piperizine derivatives. Let's get this title changed in accordance. Bradgon ( talk) 05:16, 16 November 2013 (UTC)
Pretty sure. That is unfortunate. It's the only WHO source I could find on this matter. If you can find another international source I'd be interested. Bradgon ( talk) 17:34, 18 November 2013 (UTC)
-izine is used for ALL diphenylmethyl piperizine derivatives, therefore meclizine is included in this. Bradgon ( talk) 20:45, 19 November 2013 (UTC)
The side effects in this article look rather tame... yet if I look up the anticholinergics, it indicates a vast list of rather terrifying side effects. Is there a reason these side effects were not inherited into the article? This article makes the drug look rather rosey. If this drug does not possess those side-effects, then maybe it should be noted that meclizine is a special piperazine that doesn't exhibit these side effects... — Preceding unsigned comment added by 173.59.124.60 ( talk) 04:09, 13 May 2017 (UTC)
Wikipedia says "The recommended dose is 25–50 mg orally, taken one hour before travel". Source? Even if the package leaflet claims 25-50mg, it may not be optimal dose unless proven by a study one can find from PubMed. If Meclizine is effective for example with 10mg dose, it would mean less side-effects.
ee1518 ( talk) 17:00, 30 November 2017 (UTC)
In this edit, User:Doc James added "the feeling like the world is spinning", pipe-linked to vertigo, as one of the uses of Meclizine.
While this isn't quite ungrammatical, it is both informal and awkward. And I think the word "vertigo" is fine for a lede. It's used in the lede for articles for many other vertigo medications, like betahistine. And the link given as a reference for "the feeling like the world is spinning" mentions "vertigo" but doesn't mention anything close to the wording given here. If anyone really thinks the word is too technical, I'm sure the vertigo article has a nice short description that can be borrowed, but I doubt it's necessary.
I went with "symptoms of vertigo" rather than "vertigo" itself. This seems a little over-precise to me, but most of the other vertigo meds uee similar wording. -- 157.131.246.136 ( talk) 06:02, 5 July 2019 (UTC)
![]() | This article is rated Start-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||
|
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Meclizine.
|
![]() | This article contains a translation of Meclozin from de.wikipedia. ( 403156633 et seq.) |
I tagged for cleanup because an information box was showing up on top of the article text. I don't have the personal knowhow to clean that up. Justin Z 18:16, 2 April 2007 (UTC)
I object to the term 'methadone addict'. I'm sure some users of street-methadone potentiate with meclizine, but I believe that some of those in methadone maintenance programs do as well. I don't think those in methadone maintenance should be called 'methadone addicts', regardless of the fact that they are physically addicted to methadone. I'm changing the term to 'methadone users'. 24.196.111.104 ( talk) 00:21, 3 June 2009 (UTC
The following text was lost, apparently due to a copypaste page move on 8 November 2010.
-- ἀνυπόδητος ( talk) 19:16, 17 December 2010 (UTC)
I know that this was added well over 2 years ago, but I appreciate that you've added this information here. I just don't understand why it's not on the main Meclozine Wiki page, though. I was looking all over the place trying to find some type of mechanism of action/usage/etc. comparison between meclizine and the other drugs in this family, particularly hydroxyzine, beyond the label uses of nausea and dizziness caused by motion sickness, such as comparison of meclizine to the others (again, particularly hydroxyzine) in effectiveness as an antihistamine and specific antihistamine action (which I'm surprised I couldn't find anything about besides here, considering that they're all in the same family, which is first-generation *antihistamines*), any anti-pruritic actions, possible anti-anxiety actions comparable to hydroxyzine, any possible comparable potentiating actions co-administered with opioid analgesics with hydroxyzine and promethazine (no, it's not for recreational use. I take 24/7 pain meds for chronic pain and I have a high tolerance to my pain medications, even when I take my breakthrough pain med, but I'm still rather young, and have a list of numerous surgeries I'm expecting over the course of the net few years, so I'm looking for ways to potentiate my pain meds, so I can either take less of a dose of my BT med, and/or lessen the frequency and perhaps just take a potentiating drug for the milder BT pain taken only with my long-acting medication that's taken on a schedule and always in my system at the same level, as I'm wondering if I were to take a drug that potentiates analgesia from opiates [one that actually *does* increase analgesia from opiates, at least for me] by itself, and just with my long-acting pain medication, if the potentiating/adjuvant drug would work enough just with my long-acting medication taking it "alone", rather than with the BT pain medication, that it would work taken "alone" as an analgesic for the least severe breakthrough pain that I would take an extra pain medication for. I figure anything in this drug family, or just anything that supposedly potentiates opiate analgesia, would all be at least one step up from Tylenol in effectiveness, since that doesn't work for me at all.). This is the only place I could find any kind of information like that, though. I'd totally forgotten about the "talk" page on Wikipedia topic pages until just now, too, so I spent much more time searching around for something I could have just read here in the first 5 minutes of my search, because this was the first search result I clicked on. The information you've added here really needs to be added onto the main Meclozine page, too, because when I did a Google search for Meclizine (how it's spelled on the boxes I just got from the store), the Wikipedia result automatically goes to this result, spelled Meclozine, so anyone who does an internet search for meclizine using either spelling will automatically be led to this page so even if this information might be elsewhere on here, I would assume the majority of people would never see the additional information that's stated here, maybe also on some other page elsewhere, because the majority of people using Wikipedia don't click on the "talk" link on the top of the page, or even see it there or know it's there in the first place. Just look at me-I'm signed up here, I know the talk pages are there, I've browsed the "talk" sections plenty of times before, but I went quite a long time before making my way here and seeing this cut-off info, that happens to contain exactly the information I spent a long time looking for, because it totally slipped my mind to look here. Someone needs to edit this page and copy all the drug effects listed here onto the main page. And considering that it was added over 2 years ago, it's been too long of a wait already. Hopefully someone with much more authority than myself to edit pages here will soon read this and finally edit in this additional information. --
Poisonalice (
talk) 10:34, 17 February 2013 (UTC)
Thanks, it's much appreciated, and I'm sure that there will be other people who will come along and appreciate the information added back as well. I'm sure that there will also be someone that will come along and provide the needed citations, as well. Thanks for the well wishes. It does help to a certain degree. I have degenerative disc disease, numerous herniated and degenerating discs up and down my spine, sciatica from breaking my tailbone so many times, fibromyalgia, carpal tunnel in both hands, tendinitis, shoulder separation, and arthritis in my left shoulder (I need surgery on it), and bone spurs on my right knee from an old injury and surgery, which I also need (another) surgery on to scrape the bones spurs off my kneecap. There may be one or two things missing from that list LOL! SO yeah, I'm on some pretty heavy duty pain medications, but I have high tolerances to all medications, and I develop tolerances very fast, too, probably because I'm a fast metabolizer of drugs. Thanks for asking :) I'm sure I gave you more information than you expected though HAHA! Poisonalice ( talk) 03:06, 8 March 2013 (UTC)
The drug is "Meclizine," not "Meclozine." At least in English-speaking countries...for which this article is intended. — Preceding unsigned comment added by 67.79.29.210 ( talk) 18:45, 18 October 2012 (UTC)
My apologies. You are obviously correct. — Preceding unsigned comment added by 50.84.64.2 ( talk) 17:48, 25 October 2012 (UTC)
The previous user was correct; it is indeed Meclizine per WHO INN's. See http://whqlibdoc.who.int/hq/1997/WHO_PHARM_S_NOM_1570.pdf -izine: diphenylmethyl piperizine derivatives. Let's get this title changed in accordance. Bradgon ( talk) 05:16, 16 November 2013 (UTC)
Pretty sure. That is unfortunate. It's the only WHO source I could find on this matter. If you can find another international source I'd be interested. Bradgon ( talk) 17:34, 18 November 2013 (UTC)
-izine is used for ALL diphenylmethyl piperizine derivatives, therefore meclizine is included in this. Bradgon ( talk) 20:45, 19 November 2013 (UTC)
The side effects in this article look rather tame... yet if I look up the anticholinergics, it indicates a vast list of rather terrifying side effects. Is there a reason these side effects were not inherited into the article? This article makes the drug look rather rosey. If this drug does not possess those side-effects, then maybe it should be noted that meclizine is a special piperazine that doesn't exhibit these side effects... — Preceding unsigned comment added by 173.59.124.60 ( talk) 04:09, 13 May 2017 (UTC)
Wikipedia says "The recommended dose is 25–50 mg orally, taken one hour before travel". Source? Even if the package leaflet claims 25-50mg, it may not be optimal dose unless proven by a study one can find from PubMed. If Meclizine is effective for example with 10mg dose, it would mean less side-effects.
ee1518 ( talk) 17:00, 30 November 2017 (UTC)
In this edit, User:Doc James added "the feeling like the world is spinning", pipe-linked to vertigo, as one of the uses of Meclizine.
While this isn't quite ungrammatical, it is both informal and awkward. And I think the word "vertigo" is fine for a lede. It's used in the lede for articles for many other vertigo medications, like betahistine. And the link given as a reference for "the feeling like the world is spinning" mentions "vertigo" but doesn't mention anything close to the wording given here. If anyone really thinks the word is too technical, I'm sure the vertigo article has a nice short description that can be borrowed, but I doubt it's necessary.
I went with "symptoms of vertigo" rather than "vertigo" itself. This seems a little over-precise to me, but most of the other vertigo meds uee similar wording. -- 157.131.246.136 ( talk) 06:02, 5 July 2019 (UTC)