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The dose section is contrary to what my Pediatrician just prescribed for my child's pinworm infection. We were prescribed 2 x 100mg tablets to be taken two weeks apart. This at least partially contradicts the dose section. It appears inaccurate and has no citations.
—Preceding unsigned comment added by 72.85.131.243 ( talk) 02:46, 11 June 2009 (UTC)
I too had a different dosage... My doctors have given me 2x100 mg a day, for 3 days
70.164.194.201 ( talk) 15:47, 24 August 2010 (UTC)
Mebendazole blocks polymixin based microtubule formation, destroying the glucose uptake receptor in the nematode. This article is poorly written and incorrect.
What exactly is the mechanism of action of this drug, the article mentions both glucose uptake inhabition and preventing spindle formation, vastly different actions. Which is it? Both?
Onco_p53 00:00, 16 March 2006 (UTC)
I agree that this is an incredibly badly written page. What does "selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell" mean? That the drug prevents the host's intestine from absorbing these nutrients? So it kills the patient?
The manufacturers website says that it prevents the worms taking up glucose and they die because of lack of energy.
Comrinec ( talk) 01:51, 1 August 2008 (UTC)
Image filenames ends in .svg.png which, when the content is emailed, is identified as an attempt to hide the file ending by some email malware scanners. Please re-name all the image files, removing the .svg parts! -- Leif Erlingsson ( talk) 15:45, 16 October 2012 (UTC)
The main links, like CAS registry, have no information about history of discover and/or massive use. PS: the "Date of Entry" (1974) of CAS is not the "entry year". -- Krauss ( talk) 19:05, 29 December 2013 (UTC)
In Brazil 400 mg Albendazole costs about US$2.00.
— Preceding unsigned comment added by 177.105.203.119 ( talk) 00:10, 24 January 2017 (UTC)
Which is it? Currently the article claims both:
“In the United States a single dose is about 18 USD.[3]”
“In the United States a single dose is about 440.00 USD as of 2016, while in Australia and the UK it costs about 5 USD.[8]”
— Preceding unsigned comment added by Polarbear ed ( talk • contribs) 13:30, 25 February 2018 (UTC)
It will be beneficial to the future of international standardization
Product information from Boots https://www.boots.com/ovex-suspension-30ml-family-pack-10068980
Information leaflet by Ovex https://www.medicines.org.uk/emc/files/pil.1766.pdf
Pharmaceutical page by emc https://www.medicines.org.uk/emc/product/1766/smpc
2.124.248.60 ( talk) 17:13, 13 May 2019 (UTC)
https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+3232
Human Toxicity Excerpts
Drug Warnings
Populations at Special Risk
Probable Routes of Human Exposure
Non-Human Toxicity Excerpts
Non-Human Toxicity Values
Metabolism/Metabolites
Absorption, Distribution & Excretion
Biological Half-Life
Mechanism of Action
Interactions
2.124.248.60 ( talk) 18:38, 13 May 2019 (UTC)
Under the Cost subcategory there is this line: "In Australia 6 x 100mg costs approximately US$9 while in the UK this would cost around US$19.[20] and about US$5 in Europe." With the citation linking to an FT article locked behind a paywall. Currently in the UK Mebendazole under the Ovex brand (100mg x 4 tablet dose) are sold online for £6, £6 is about $8 US or just over $11 Australian.
( https://ayp.healthcare/ovex-family-pack-4-threadworm-treatment-tablets) for an example.
In pharmacies in the UK it is often cheaper, but I cannot give you an exact figure. So it seems as though if the $18 price is written in that FT article, it is either incorrect or out of date.
There is no indication in the use of mebendazole for the treatment of giardia — Preceding unsigned comment added by 87.117.189.244 ( talk) 17:39, 6 January 2022 (UTC)
This is the
talk page for discussing improvements to the
Mebendazole article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
![]() | It is requested that a photograph be
included in this article to
improve its quality.
The external tool WordPress Openverse may be able to locate suitable images on Flickr and other web sites. |
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Mebendazole.
|
The dose section is contrary to what my Pediatrician just prescribed for my child's pinworm infection. We were prescribed 2 x 100mg tablets to be taken two weeks apart. This at least partially contradicts the dose section. It appears inaccurate and has no citations.
—Preceding unsigned comment added by 72.85.131.243 ( talk) 02:46, 11 June 2009 (UTC)
I too had a different dosage... My doctors have given me 2x100 mg a day, for 3 days
70.164.194.201 ( talk) 15:47, 24 August 2010 (UTC)
Mebendazole blocks polymixin based microtubule formation, destroying the glucose uptake receptor in the nematode. This article is poorly written and incorrect.
What exactly is the mechanism of action of this drug, the article mentions both glucose uptake inhabition and preventing spindle formation, vastly different actions. Which is it? Both?
Onco_p53 00:00, 16 March 2006 (UTC)
I agree that this is an incredibly badly written page. What does "selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell" mean? That the drug prevents the host's intestine from absorbing these nutrients? So it kills the patient?
The manufacturers website says that it prevents the worms taking up glucose and they die because of lack of energy.
Comrinec ( talk) 01:51, 1 August 2008 (UTC)
Image filenames ends in .svg.png which, when the content is emailed, is identified as an attempt to hide the file ending by some email malware scanners. Please re-name all the image files, removing the .svg parts! -- Leif Erlingsson ( talk) 15:45, 16 October 2012 (UTC)
The main links, like CAS registry, have no information about history of discover and/or massive use. PS: the "Date of Entry" (1974) of CAS is not the "entry year". -- Krauss ( talk) 19:05, 29 December 2013 (UTC)
In Brazil 400 mg Albendazole costs about US$2.00.
— Preceding unsigned comment added by 177.105.203.119 ( talk) 00:10, 24 January 2017 (UTC)
Which is it? Currently the article claims both:
“In the United States a single dose is about 18 USD.[3]”
“In the United States a single dose is about 440.00 USD as of 2016, while in Australia and the UK it costs about 5 USD.[8]”
— Preceding unsigned comment added by Polarbear ed ( talk • contribs) 13:30, 25 February 2018 (UTC)
It will be beneficial to the future of international standardization
Product information from Boots https://www.boots.com/ovex-suspension-30ml-family-pack-10068980
Information leaflet by Ovex https://www.medicines.org.uk/emc/files/pil.1766.pdf
Pharmaceutical page by emc https://www.medicines.org.uk/emc/product/1766/smpc
2.124.248.60 ( talk) 17:13, 13 May 2019 (UTC)
https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+3232
Human Toxicity Excerpts
Drug Warnings
Populations at Special Risk
Probable Routes of Human Exposure
Non-Human Toxicity Excerpts
Non-Human Toxicity Values
Metabolism/Metabolites
Absorption, Distribution & Excretion
Biological Half-Life
Mechanism of Action
Interactions
2.124.248.60 ( talk) 18:38, 13 May 2019 (UTC)
Under the Cost subcategory there is this line: "In Australia 6 x 100mg costs approximately US$9 while in the UK this would cost around US$19.[20] and about US$5 in Europe." With the citation linking to an FT article locked behind a paywall. Currently in the UK Mebendazole under the Ovex brand (100mg x 4 tablet dose) are sold online for £6, £6 is about $8 US or just over $11 Australian.
( https://ayp.healthcare/ovex-family-pack-4-threadworm-treatment-tablets) for an example.
In pharmacies in the UK it is often cheaper, but I cannot give you an exact figure. So it seems as though if the $18 price is written in that FT article, it is either incorrect or out of date.
There is no indication in the use of mebendazole for the treatment of giardia — Preceding unsigned comment added by 87.117.189.244 ( talk) 17:39, 6 January 2022 (UTC)