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I just noticed that the nice structure picture of the single immunoglobulin domain is actually a fibronectin domain from tenascin. Although technically it has the same beta sandwich structure it does not belong to the immunoglobulin superfamily. Alexbateman ( talk) 15:52, 20 January 2009 (UTC)
In the introduction it mentions that Ig domains are cell surface or soluble. While this is largely true there are a few rare cases of intracellular Ig domains such as in the giant muscle protein titin. I'm not sure that this really needs explicitly mentioning in the introduction. But a slight reword could be useful. Alexbateman ( talk) 11:41, 12 June 2009 (UTC)
Article makes no mention of the LIR family of receptors (e.g. LILRB4, LILRA4, etc.). SteveChervitzTrutane ( talk) 23:28, 22 November 2010 (UTC)
Thanks for the comment. I don't think the article about the Ig superfamily should be comprehensive. There are literally thousands of example proteins to choose from. However, if there was some aspect of the LIR family biology that was illustrative of the superfamily then they might be worth a mention. Any thoughts on that or other ways to improve this article? Alexbateman ( talk) 10:45, 23 November 2010 (UTC)
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||
|
I just noticed that the nice structure picture of the single immunoglobulin domain is actually a fibronectin domain from tenascin. Although technically it has the same beta sandwich structure it does not belong to the immunoglobulin superfamily. Alexbateman ( talk) 15:52, 20 January 2009 (UTC)
In the introduction it mentions that Ig domains are cell surface or soluble. While this is largely true there are a few rare cases of intracellular Ig domains such as in the giant muscle protein titin. I'm not sure that this really needs explicitly mentioning in the introduction. But a slight reword could be useful. Alexbateman ( talk) 11:41, 12 June 2009 (UTC)
Article makes no mention of the LIR family of receptors (e.g. LILRB4, LILRA4, etc.). SteveChervitzTrutane ( talk) 23:28, 22 November 2010 (UTC)
Thanks for the comment. I don't think the article about the Ig superfamily should be comprehensive. There are literally thousands of example proteins to choose from. However, if there was some aspect of the LIR family biology that was illustrative of the superfamily then they might be worth a mention. Any thoughts on that or other ways to improve this article? Alexbateman ( talk) 10:45, 23 November 2010 (UTC)