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Two citations were given to support the statement that zinc finger nucleases make frequent unwanted cuts in the genome. The first citation, Ramirez et al., deals with non-modular behavior when individual zinc fingers are joined. I could not find anything in this paper to support the statement about unwanted cuts in the genome. The second reference, Petek et al., deals with genome cuts due to the homing endonuclease I-SceI. I-SceI is not a zinc finger nuclease. ScienceGeekling ( talk) 03:49, 16 February 2011 (UTC)
Somebody should write a paragraph about CRISPR genome editing. AxelBoldt ( talk) 00:46, 22 December 2013 (UTC)
Duplicate material between genome editing and genome engineering noticed and reported here. It looks like the pages could be sensibly merged to bring the information together and better define the terminology. T.Shafee(Evo﹠Evo) talk 23:55, 14 April 2015 (UTC)
There seems to be a general consensus for merging. Doing so will be quite an effort. I can't really commit to getting around to it this year, but I will see if I can contact some qualified academics to help out. T.Shafee(Evo&Evo) talk 00:14, 1 November 2016 (UTC)
Per the merge debate above, I'm a little concerned about the origins of this article, which may perhaps be part of COI editing on behalf of a company with an interest in one specific method of genome engineering. I think it would be as well for a neutral and informed editor to review the content as part of a merge. Per the citation thread at the top of this page, it is possible that the company with COI interest, Cellectis, is seeking to promote its interest in Meganuclease in part by criticising other techniques. See also Wikipedia:Conflict_of_interest/Noticeboard#Cellectis. -- Tagishsimon (talk) 17:01, 18 March 2016 (UTC)
Genome editing ( | talk | history | protect | delete | links | watch | logs | views) -- large insert of COI in this edit, beyond my pay-grade. Per Genome Engineering report, below, I've added notes to the article talk & an interested wikiproject. -- Tagishsimon (talk) 17:20, 18 March 2016 (UTC) Genome engineering ( | talk | history | protect | delete | links | watch | logs | views) -
- not sure what to make. Article starts as a large insert by an editor never heard from again, followed quickly by some Sofike68 edits. It may be per its talk that the article in part seeks to promote Meganuclease in part by criticising another technique. I've removed some text promoting Cellectis, contributed to a merge debate suggesting the article should be reviewed, and pointed to this COI discussion on the article talk page & at Wikipedia talk:WikiProject Molecular and Cell Biology -- Tagishsimon (talk) 16:58, 18 March 2016 (UTC)
There are a few main issues on this page:
I'll have a go at some of these (and similar issues in the Genome editing article) in the next few weeks. As always, I'm happy for any help! T.Shafee(Evo﹠Evo) talk 12:11, 25 April 2016 (UTC)
This is the
talk page for discussing improvements to the
Genome engineering redirect. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find sources: Google ( books · news · scholar · free images · WP refs) · FENS · JSTOR · TWL |
![]() | Individuals with a conflict of interest, particularly those representing the subject of the article, are strongly advised not to directly edit the article. See Wikipedia:Conflict of interest. You may request corrections or suggest content here on the Talk page for independent editors to review, or contact us if the issue is urgent. |
![]() | This redirect does not require a rating on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||
|
![]() | Text and/or other creative content from this version of Genome engineering was copied or moved into Genome editing with this edit. The former page's history now serves to provide attribution for that content in the latter page, and it must not be deleted as long as the latter page exists. |
![]() | The
Wikimedia Foundation's
Terms of Use require that editors disclose their "employer, client, and affiliation" with respect to any paid contribution; see
WP:PAID. For advice about reviewing paid contributions, see
WP:COIRESPONSE. Edits made by the below user(s) were last checked for neutrality on 3 April 2016 by T.Shafee(Evo﹠Evo) talk.
|
Two citations were given to support the statement that zinc finger nucleases make frequent unwanted cuts in the genome. The first citation, Ramirez et al., deals with non-modular behavior when individual zinc fingers are joined. I could not find anything in this paper to support the statement about unwanted cuts in the genome. The second reference, Petek et al., deals with genome cuts due to the homing endonuclease I-SceI. I-SceI is not a zinc finger nuclease. ScienceGeekling ( talk) 03:49, 16 February 2011 (UTC)
Somebody should write a paragraph about CRISPR genome editing. AxelBoldt ( talk) 00:46, 22 December 2013 (UTC)
Duplicate material between genome editing and genome engineering noticed and reported here. It looks like the pages could be sensibly merged to bring the information together and better define the terminology. T.Shafee(Evo﹠Evo) talk 23:55, 14 April 2015 (UTC)
There seems to be a general consensus for merging. Doing so will be quite an effort. I can't really commit to getting around to it this year, but I will see if I can contact some qualified academics to help out. T.Shafee(Evo&Evo) talk 00:14, 1 November 2016 (UTC)
Per the merge debate above, I'm a little concerned about the origins of this article, which may perhaps be part of COI editing on behalf of a company with an interest in one specific method of genome engineering. I think it would be as well for a neutral and informed editor to review the content as part of a merge. Per the citation thread at the top of this page, it is possible that the company with COI interest, Cellectis, is seeking to promote its interest in Meganuclease in part by criticising other techniques. See also Wikipedia:Conflict_of_interest/Noticeboard#Cellectis. -- Tagishsimon (talk) 17:01, 18 March 2016 (UTC)
Genome editing ( | talk | history | protect | delete | links | watch | logs | views) -- large insert of COI in this edit, beyond my pay-grade. Per Genome Engineering report, below, I've added notes to the article talk & an interested wikiproject. -- Tagishsimon (talk) 17:20, 18 March 2016 (UTC) Genome engineering ( | talk | history | protect | delete | links | watch | logs | views) -
- not sure what to make. Article starts as a large insert by an editor never heard from again, followed quickly by some Sofike68 edits. It may be per its talk that the article in part seeks to promote Meganuclease in part by criticising another technique. I've removed some text promoting Cellectis, contributed to a merge debate suggesting the article should be reviewed, and pointed to this COI discussion on the article talk page & at Wikipedia talk:WikiProject Molecular and Cell Biology -- Tagishsimon (talk) 16:58, 18 March 2016 (UTC)
There are a few main issues on this page:
I'll have a go at some of these (and similar issues in the Genome editing article) in the next few weeks. As always, I'm happy for any help! T.Shafee(Evo﹠Evo) talk 12:11, 25 April 2016 (UTC)