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As a non-native English speaker, I have to ask: would the usage of "ze" and "hir" as neutral pronouns be inacceptable in this context? "It"/"its" suggests an inhumanity that is entirely unsuggested by the work; Desire may be cruel, but it is in no way implied that he/she is in any way less "human" (or, lets say, less humanly treated|depicted|constructed) than any of his/her brothers and sisters. Zeppocity ( talk) 04:01, 22 January 2008 (UTC) reply

Desire is directly referred to as "it" in the comic (see the Brief Lives arc), although not by any of the other Endless as far as I can remember. Since the neutral pronouns were never used in the comic, I see no reason to introduce them in the article. Willbyr ( talk | contribs) 16:37, 22 January 2008 (UTC) reply

Morpheus DOES refer to Desire as “It” in the prologue to “Season of Mists”. - R.G. ( talk) 16:10, 18 January 2018 (UTC) reply